ncPRC1RYBP bound to H2AK119Ub/H1.4 chromatosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9dde
Q-score: 0.456
Lopez VG, Valencia-Sanchez MI, Abini-Agbomson S, Thomas JF, Lee R, De Ioannes P, Sosa BA, Armache JP, Armache KJ
Nature (2024) 636 pp. 755-761 [ DOI: doi:10.1038/s41586-024-08183-5 Pubmed: 39537923 ]
- Histone h4 (Complex from Xenopus laevis)
- Histone h1.4 (Complex from Homo sapiens)
- Histone h1.4 (21 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h2a (Complex from Xenopus laevis)
- Ring1 and yy1-binding protein (Complex from Homo sapiens)
- Ncprc1rybp bound to h2ak119ub/h1.4 chromatosome (Complex from Homo sapiens)
- Dna (Complex from synthetic construct)
- E3 ubiquitin-protein ligase ring2 (37 kDa, Protein from Homo sapiens)
- Histone h2b 1.1 (Complex from Xenopus laevis)
- Histones (Complex from Xenopus laevis)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- E3 ubiquitin-protein ligase ring2, ubiquitin-conjugating enzyme e2 d3 (Complex from Homo sapiens)
- Dna (187-mer) (Complex from synthetic construct)
- Dna (187-mer) (57 kDa, DNA from synthetic construct)
- Ncprc1-rybp (Complex from Homo sapiens)
- Dna (187-mer) (57 kDa, DNA from synthetic construct)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Zinc ion (65 Da, Ligand)
- Polycomb complex protein bmi-1 (37 kDa, Protein from Homo sapiens)
- Ring1 and yy1-binding protein (24 kDa, Protein from Homo sapiens)
- Ubiquitin (Complex from Homo sapiens)
- Histone h3.2 (Complex from Xenopus laevis)
- Polycomb complex protein bmi-1 (Complex from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
Cryo-EM structure of FoxA1 and GATA4 in complex with H14 chromatosome
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8vg2
Q-score: 0.493
Mol Cell (2024) [ ]
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Dna (196-mer) (65 kDa, DNA from synthetic construct)
- Histone h1.4 (22 kDa, Protein from Homo sapiens)
- Foxa1 and gata4 in complex with h1.4 chromatosome (Complex from Homo sapiens)
- Hepatocyte nuclear factor 3-alpha (50 kDa, Protein from Homo sapiens)
- Dna (196-mer) (64 kDa, DNA from synthetic construct)
Cryo-EM structure of BAP1-ASXL1 bound to chromatosome
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8h1t
Q-score: 0.435
Ge W, Yu C, Li J, Yu Z, Li X, Zhang Y, Liu CP, Li Y, Tian C, Zhang X, Li G, Zhu B, Xu RM
Nature (2023) 616 pp. 176-182 [ Pubmed: 36991118 DOI: doi:10.1038/s41586-023-05841-y ]
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h2b type 2-e (13 kDa, Protein from Homo sapiens)
- Dna (187-mer) (57 kDa, DNA from Homo sapiens)
- Histone h2a type 1-d (14 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Dna (187-mer) (58 kDa, DNA from Homo sapiens)
- Polycomb group protein asxl1 (41 kDa, Protein from Homo sapiens)
- Cryo-em structure of bap1-asxl1 bound to chromatosome (Complex from Homo sapiens)
- Ubiquitin carboxyl-terminal hydrolase bap1 (80 kDa, Protein from Homo sapiens)
- Histone h1.4 (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of a chromatosome containing human linker histone H1.4
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7k5y
Q-score: 0.527
Zhou BR, Feng H, Kale S, Fox T, Khant H, de Val N, Ghirlando R, Panchenko AR, Bai Y
Mol Cell (2021) 81 pp. 166-182.e6 [ Pubmed: 33238161 DOI: doi:10.1016/j.molcel.2020.10.038 ]
- Chromatosome containing human linker histone h1.4 (Complex from human)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Dna (197-mer) (61 kDa, DNA from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Dna (197-mer) (60 kDa, DNA from Homo sapiens)
- Scfv20 (29 kDa, Protein from Mus musculus)
- Histone h1.4 (21 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
cryo-EM map of di-chromatosome containing H1.4
Zhou BR, Feng H, Kale S, Fox T, Khant H, de Val N, Ghirlando R, Panchenko AR, Bai Y
Mol Cell (2021) 81 pp. 166-182.e6 [ Pubmed: 33238161 DOI: doi:10.1016/j.molcel.2020.10.038 ]
- Dna (394-mer) (Protein from Homo sapiens)
- Scfv20 (Protein from Mougeotia scalaris)
- Human histone h1.4 (Protein from Homo sapiens)
- Human histone h2b1j (Protein from Homo sapiens)
- Di-chromatosome containing human linker histone h1.4 (Complex from human)
- Human histone h4 (Protein from Homo sapiens)
- Human histone h2a1 (Protein from Homo sapiens)
- Dna(394-mer) (Protein from Homo sapiens)
- Human histone h3.1 (Protein from Homo sapiens)