Resolution: 4.43 Å
EM Method: Single-particle
Fitted PDBs: 6z6p
Q-score: 0.189
Lee JH, Bollschweiler D, Schafer T, Huber R
Sci Adv (2021) 7 [ DOI: doi:10.1126/sciadv.abd4413 Pubmed: 33523989 ]
- Histone deacetylase hda1 (74 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (145-mer) (44 kDa, DNA from unidentified plasmid)
- Histone deacetylase (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone deacetylase hda1 (76 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone h2b (10 kDa, Protein from Xenopus laevis)
- Dna (145-mer) (44 kDa, DNA from unidentified plasmid)
- Histone (Complex from Xenopus laevis)
- Dna (Complex from unidentified plasmid)
- Histone h2b (10 kDa, Protein from Xenopus laevis)
- Hdac-pc-nuc (Complex)
- Hda1 complex subunit 2 (71 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Histone h3 (11 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (11 kDa, Protein from Xenopus laevis)
- Histone h2a (11 kDa, Protein from Xenopus laevis)
- Hda1 complex subunit 3,hda1 complex subunit 3 (63 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone h3.2 (11 kDa, Protein from Xenopus laevis)
- Histone h4 (9 kDa, Protein from Xenopus laevis)
- Histone h4 (8 kDa, Protein from Xenopus laevis)
Active state Dot1 bound to the unacetylated H4 nucleosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7k6p
Q-score: 0.473
Valencia-Sanchez MI, De Ioannes P, Wang M, Truong DM, Lee R, Armache JP, Boeke JD, Armache KJ
Science (2021) 371 [ Pubmed: 33479126 DOI: doi:10.1126/science.abc6663 ]
- Polyubiquitin-b (Complex from Homo sapiens)
- Histone h4 (10 kDa, Protein from Xenopus laevis)
- Dna (146-mer) (44 kDa, DNA from synthetic construct)
- Histone h2b 1.1 (10 kDa, Protein from Xenopus laevis)
- Active state dot1 bound to the unacetylated h4 nucleosome (Complex from Saccharomyces cerevisiae)
- S-adenosylmethionine (398 Da, Ligand)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (Complex from Saccharomyces cerevisiae)
- Histone h2a type 1 (11 kDa, Protein from Xenopus laevis)
- Dna (146-mer) (45 kDa, DNA from synthetic construct)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (46 kDa, Protein from Saccharomyces cerevisiae)
- Dna (146-mer) (Complex from synthetic construct)
- Histones (Complex from Xenopus laevis)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h3.2 (11 kDa, Protein from Xenopus laevis)
Active state Dot1 bound to the H4K16ac nucleosome
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7k6q
Q-score: 0.489
Valencia-Sanchez MI, De Ioannes P, Wang M, Truong DM, Lee R, Armache JP, Boeke JD, Armache KJ
Science (2021) 371 [ Pubmed: 33479126 DOI: doi:10.1126/science.abc6663 ]
- Polyubiquitin-b (Complex from Homo sapiens)
- Active state dot1 bound to the h4k16ac nucleosome (Complex from Saccharomyces cerevisiae)
- Dna (146-mer) (44 kDa, DNA from synthetic construct)
- Histone h2b 1.1 (10 kDa, Protein from Xenopus laevis)
- S-adenosylmethionine (398 Da, Ligand)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (Complex from Saccharomyces cerevisiae)
- Histone h2a type 1 (11 kDa, Protein from Xenopus laevis)
- Dna (146-mer) (45 kDa, DNA from synthetic construct)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (46 kDa, Protein from Saccharomyces cerevisiae)
- Histones (Complex from Xenopus laevis)
- Histone h4 (10 kDa, Protein from Xenopus laevis)
- Dna (146-mer) (Complex from Synthetic construct)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h3.2 (11 kDa, Protein from Xenopus laevis)