SIRT7:H3K18DTU nucleosome complex
Carlos MY, Babatunde E, Polina F, Esther S, Dongchun N, Henning S, Beat F
To Be Published
- K18 structure (Complex from Homo sapiens)
- Dna (148-mer) (45 kDa, DNA from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Dna (148-mer) (45 kDa, DNA from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Histone h2a type 2-a (13 kDa, Protein from Homo sapiens)
- Nad-dependent protein deacetylase sirtuin-7 (45 kDa, Protein from Homo sapiens)
SIRT7-H3K36MTUnucleosome complex
Carlos MY, Babatunde E, Polina F, Esther S, Dongchun N, Henning S, Beat F
To Be Published
- Zinc ion (65 Da, Ligand)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- [[(2~{r},3~{a}~{r},5~{r},6~{r},6~{a}~{r})-2-(methylamino)-6-oxidanyl-2-(propylamino)-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxathiol-5-yl]methoxy-oxidanyl-phosphoryl] [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (673 Da, Ligand)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- K36 structure (Complex from Homo sapiens)
- Histone h2a type 2-a (13 kDa, Protein from Homo sapiens)
- Dna (149-mer) (46 kDa, DNA from Homo sapiens)
- Nad-dependent protein deacetylase sirtuin-7 (45 kDa, Protein from Homo sapiens)
- Dna (149-mer) (45 kDa, DNA from Homo sapiens)
Cryo-EM structure of 186bp ALBN1 nucleosome aided by scFv
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8vfx
Q-score: 0.559
Zhou BR, Feng H, Huang F, Zhu I, Portillo-Ledesma S, Shi D, Zaret KS, Schlick T, Landsman D, Wang Q, Bai Y
Mol Cell (2024) 84 pp. 3061- [ Pubmed: 39121853 DOI: doi:10.1016/j.molcel.2024.07.016 ]
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Dna (158-mer) (57 kDa, DNA from synthetic construct)
- 186bp albn1 nucleosome in complex with scfv (Complex from Homo sapiens)
- Dna (158-mer) (57 kDa, DNA from synthetic construct)
- Scfv (29 kDa, Protein from Mus musculus)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 1)
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8vfy
Q-score: 0.463
Zhou BR, Feng H, Huang F, Zhu I, Portillo-Ledesma S, Shi D, Zaret KS, Schlick T, Landsman D, Wang Q, Bai Y
Mol Cell (2024) 84 pp. 3061- [ Pubmed: 39121853 DOI: doi:10.1016/j.molcel.2024.07.016 ]
- Dna (171-mer) (57 kDa, DNA from synthetic construct)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Dna (171-mer) (57 kDa, DNA from synthetic construct)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Foxa1 in complx with 186bp albn1 nucleosome (Complex from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Hepatocyte nuclear factor 3-alpha (50 kDa, Protein from Homo sapiens)
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 2)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8vfz
Q-score: 0.27
Zhou BR, Feng H, Huang F, Zhu I, Portillo-Ledesma S, Shi D, Zaret KS, Schlick T, Landsman D, Wang Q, Bai Y
Mol Cell (2024) 84 pp. 3061- [ Pubmed: 39121853 DOI: doi:10.1016/j.molcel.2024.07.016 ]
- Dna (171-mer) (57 kDa, DNA from synthetic construct)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Dna (171-mer) (57 kDa, DNA from synthetic construct)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Foxa1 in complx with 186bp albn1 nucleosome (Complex from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Hepatocyte nuclear factor 3-alpha (50 kDa, Protein from Homo sapiens)
Cryo-EM structure of GATA4 in complex with ALBN1 nucleosome
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8vg0
Q-score: 0.482
Zhou BR, Feng H, Huang F, Zhu I, Portillo-Ledesma S, Shi D, Zaret KS, Schlick T, Landsman D, Wang Q, Bai Y
Mol Cell (2024) 84 pp. 3061- [ Pubmed: 39121853 DOI: doi:10.1016/j.molcel.2024.07.016 ]
- Zinc ion (65 Da, Ligand)
- Maltose/maltodextrin-binding periplasmic protein,transcription factor gata-4 (87 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Dna (159-mer) (57 kDa, DNA from synthetic construct)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Dna (159-mer) (57 kDa, DNA from synthetic construct)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Gata4 in complex with 186bp albn1 nucleosome (Complex from Homo sapiens)
Cryo-EM structure of FoxA1 and GATA4 in complex with ALBN1 nucleosome
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 8vg1
Q-score: 0.541
Zhou BR, Feng H, Huang F, Zhu I, Portillo-Ledesma S, Shi D, Zaret KS, Schlick T, Landsman D, Wang Q, Bai Y
Mol Cell (2024) 84 pp. 3061- [ Pubmed: 39121853 DOI: doi:10.1016/j.molcel.2024.07.016 ]
- Dna (171-mer) (57 kDa, DNA from synthetic construct)
- Zinc ion (65 Da, Ligand)
- Maltose/maltodextrin-binding periplasmic protein,transcription factor gata-4 (87 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Foxa1 and gata4 in complx with 186bp albn1 nucleosome (Complex from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Dna (171-mer) (57 kDa, DNA from synthetic construct)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Hepatocyte nuclear factor 3-alpha (50 kDa, Protein from Homo sapiens)