The crosslinked complex of ISWI-nucleosome in the ADP.BeF-bound state
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 6jyl
Q-score: 0.452
Yan L, Wu H, Li X, Gao N, Chen Z
Nat Struct Mol Biol (2019) 26 pp. 258-266 [ DOI: doi:10.1038/s41594-019-0199-9 Pubmed: 30872815 ]
- Iswi (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Nucleosome (Complex from Xenopus laevis)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Histone h2a (13 kDa, Protein from Xenopus laevis)
- Beryllium trifluoride ion (66 Da, Ligand)
- Dna (167-mer) (51 kDa, DNA from Escherichia coli K-12)
- Dna (Complex from Escherichia coli K-12)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Iswi-nucleosome-crosslinked (300 kDa, Complex)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Dna (167-mer) (51 kDa, Protein from Escherichia coli K-12)
- Iswi chromatin-remodeling complex atpase isw1 (123 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Structure of Snf2-nucleosome complex in ADP state
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 5z3o
Q-score: 0.349
Li M, Xia X, Tian Y, Jia Q, Liu X, Lu Y, Li M, Li X, Chen Z
Nature (2019) 567 pp. 409-413 [ DOI: doi:10.1038/s41586-019-1029-2 Pubmed: 30867599 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Complex of snf2 and nucleosome in adp state (300 kDa, Complex from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Dna (167-mer) (51 kDa, DNA from synthetic construct)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Histone h2a (13 kDa, Protein from Xenopus laevis)
- Magnesium ion (24 Da, Ligand)
- Transcription regulatory protein snf2 (85 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (167-mer) (51 kDa, DNA from synthetic construct)
The complex of ISWI-nucleosome in the ADP.BeF-bound state
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 6k1p
Q-score: 0.42
Yan L, Wu H, Li X, Gao N, Chen Z
Nat Struct Mol Biol (2019) 26 pp. 258-266 [ DOI: doi:10.1038/s41594-019-0199-9 Pubmed: 30872815 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Nuleosome (Complex from Xenopus laevis)
- Histone h2a (13 kDa, Protein from Xenopus laevis)
- Beryllium trifluoride ion (66 Da, Ligand)
- Dna (167-mer) (51 kDa, DNA from Escherichia coli K-12)
- Dna (Complex from Escherichia coli K-12)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Dna (167-mer) (51 kDa, DNA from Escherichia coli K-12)
- Isw1 (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- The complex of iswi-nucleosome in the adp-bef-bound state (300 kDa, Complex)
- Iswi chromatin-remodeling complex atpase isw1 (123 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
the crosslinked complex of ISWI-nucleosome in the ADP-bound state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6iro
Q-score: 0.435
Yan L, Wu H, Li X, Gao N, Chen Z
Nat Struct Mol Biol (2019) 26 pp. 258-266 [ DOI: doi:10.1038/s41594-019-0199-9 Pubmed: 30872815 ]
- Histone octamer (Complex from Xenopus laevis)
- The crosslinked complex of iswi-nucleosome in the adp-bound state (Complex)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna (Complex from Escherichia coli K-12)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone h2a (13 kDa, Protein from Xenopus laevis)
- Isw1 (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (167-mer) (51 kDa, DNA from Escherichia coli K-12)
- Iswi chromatin-remodeling complex atpase isw1 (123 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (167-mer) (51 kDa, DNA from Escherichia coli K-12)
Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 6iy2
Q-score: 0.427
Li M, Xia X, Tian Y, Jia Q, Liu X, Lu Y, Li M, Li X, Chen Z
Nature (2019) 567 pp. 409-413 [ DOI: doi:10.1038/s41586-019-1029-2 Pubmed: 30867599 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transcription regulatory protein snf2 (79 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Structure of snf2-mmtv-a nucleosome complex at shl2 in adp state (300 kDa, Complex from Xenopus laevis)
- Histone h3 (11 kDa, Protein from Xenopus laevis)
- Histone h2a (12 kDa, Protein from Xenopus laevis)
- Dna (167-mer) (44 kDa, DNA from Mus musculus)
- Histone h2b (11 kDa, Protein from Xenopus laevis)
- Dna (147-mer) (45 kDa, DNA from Mus musculus)
- Histone h4 (10 kDa, Protein from Xenopus laevis)
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 1-to-1 complex
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 6nqa
Q-score: 0.436
Worden EJ, Hoffmann NA, Hicks CW, Wolberger C
Cell (2019) 176 pp. 1490-1501.e12 [ Pubmed: 30765112 DOI: doi:10.1016/j.cell.2019.02.002 ]
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Active state dot1l in complex with the h2b-ub nucleosome (Complex)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (47 kDa, Protein from Homo sapiens)
- Dot1l (Complex from Xenopus laevis)
- S-adenosylmethionine (398 Da, Ligand)
- Ubiquitin (Complex from Homo sapiens)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- H2b-ub nucleosome (Complex)
- Histone h2a type 1 (13 kDa, Protein from Xenopus laevis)
- 601 dna strand 2 (45 kDa, DNA from synthetic construct)
- Dna (Complex from synthetic construct)
- Ubiquitin (9 kDa, Protein from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- 601 dna strand 1 (44 kDa, DNA from synthetic construct)
- Histone core (Complex from Xenopus laevis)
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 6nj9
Q-score: 0.551
Worden EJ, Hoffmann NA, Hicks CW, Wolberger C
Cell (2019) 176 pp. 1490-1501.e12 [ Pubmed: 30765112 DOI: doi:10.1016/j.cell.2019.02.002 ]
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Active state dot1l in complex with the h2b-ub nucleosome (Complex)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (47 kDa, Protein from Homo sapiens)
- S-adenosylmethionine (398 Da, Ligand)
- Ubiquitin (Complex from Homo sapiens)
- H2h2b-ub nucleosome (Complex)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (13 kDa, Protein from Xenopus laevis)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Dna (Complex from synthetic construct)
- 601 dna strand 2 (45 kDa, DNA from synthetic construct)
- Ubiquitin (9 kDa, Protein from Homo sapiens)
- Dot1l (Complex from Homo sapiens)
- 601 dna strand 1 (44 kDa, DNA from synthetic construct)
- Histone core (Complex from Xenopus laevis)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6ir9
Q-score: 0.264
Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI
Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]
- Rna polymerase subunit abc10-beta, common to rna polymerases i, ii, and iii (8 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Spt5 (101 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Rna polymerase subunit abc10-alpha (7 kDa, Protein from Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1))
- Dna (198-mer) (60 kDa, DNA from synthetic construct)
- Rna polymerase subunit abc27, common to rna polymerases i, ii, and iii (24 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Rna polymerase ii subunit (18 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Transcription elongation factor spt4 (12 kDa, Protein from Komagataella phaffii)
- Rna polymerase ii elongation complex bound with elf1 and spt4/5, stalled at shl(-1) of the nucleosome (Complex from Komagataella phaffii)
- Rna (5'-r(p*gp*cp*cp*up*gp*gp*up*gp*up*cp*up*up*gp*gp*gp*u)-3') (5 kDa, RNA from synthetic construct)
- Rna polymerase ii third largest subunit b44, part of central core (34 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Dna-directed rna polymerase subunit (194 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Histone h3.3 (15 kDa, Protein from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (14 kDa, Protein from Homo sapiens)
- Rna polymerase subunit abc23, common to rna polymerases i, ii, and iii (17 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Transcription elongation factor 1 homolog (12 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Dna-directed rna polymerase subunit (13 kDa, Protein from Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1))
- Magnesium ion (24 Da, Ligand)
- Rna polymerase ii subunit b12.5 (13 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna polymerase ii subunit b32 (20 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (16 kDa, Protein from Komagataella phaffii (strain GS115 / ATCC 20864))
- Dna (198-mer) (61 kDa, DNA from synthetic construct)
Chromatin remodeller-nucleosome complex at 3.6 A resolution.
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6gej
Q-score: 0.372
Willhoft O, Ghoneim M, Lin CL, Chua EYD, Wilkinson M, Chaban Y, Ayala R, McCormack EA, Ocloo L, Rueda DS, Wigley DB
Science (2018) 362 [ DOI: doi:10.1126/science.aat7716 Pubmed: 30309918 ]
- Helicase swr1 (174 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone h2a.1 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone h3 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna (Complex from synthetic construct)
- Ruvb-like protein 1 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Remodeller (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (154-mer) (47 kDa, DNA from synthetic construct)
- Swr1-nucleosome complex (1 MDa, Complex)
- Histone h2b.1 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Actin-like protein arp6 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Histone h4 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Ruvb-like protein 2 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (154-mer) (47 kDa, DNA from synthetic construct)
- Beryllium trifluoride ion (66 Da, Ligand)
- Vacuolar protein sorting-associated protein 72 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Vacuolar protein sorting-associated protein 71 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Chromatin remodeller-nucleosome complex at 4.5 A resolution.
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6gen
Q-score: 0.195
Willhoft O, Ghoneim M, Lin CL, Chua EYD, Wilkinson M, Chaban Y, Ayala R, McCormack EA, Ocloo L, Rueda DS, Wigley DB
Science (2018) 362 [ DOI: doi:10.1126/science.aat7716 Pubmed: 30309918 ]
- Helicase swr1 (174 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histones (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Histone h2a.1 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Dna (173-mer) (53 kDa, DNA from synthetic construct)
- Histone h3 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna (Complex from synthetic construct)
- Ruvb-like protein 1 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Remodeller (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Swr1-nucleosome complex (1 MDa, Complex)
- Histone h2b.1 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Actin-like protein arp6 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Dna (173-mer) (53 kDa, DNA from synthetic construct)
- Histone h4 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Ruvb-like protein 2 (51 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Beryllium trifluoride ion (66 Da, Ligand)
- Vacuolar protein sorting-associated protein 72 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Vacuolar protein sorting-associated protein 71 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))