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sample_name:"Human 48S initiation complex"
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Structure of human 48S translation initiation complex in open codon scanning state (48S-1)

Release date: Aug. 14, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8pj1
Q-score: 0.368

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)

Release date: Aug. 14, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8pj2
Q-score: 0.32

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)

Release date: Aug. 14, 2024
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8pj3
Q-score: 0.312

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of human 48S translation initiation complex after eIF5 release (48S-4)

Release date: Aug. 14, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8pj4
Q-score: 0.361

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2025) 32 pp. 62-72 [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5)

Release date: Aug. 14, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8pj5
Q-score: 0.437

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway)

Release date: Aug. 14, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8pj6
Q-score: 0.374

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of human eIF3 core from closed 48S translation initiation complex

Release date: Aug. 14, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8rg0
Q-score: 0.303

Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV, Fischer N

Nat Struct Mol Biol (2025) 32 pp. 62-72 [ DOI: doi:10.1038/s41594-024-01378-4 Pubmed: 39289545 ]

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Structure of the human 48S initiation complex in open state (h48S AUG open)

Release date: May 11, 2022
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp6
Q-score: 0.233

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ DOI: doi:10.1093/nar/gkac283 Pubmed: 35489072 ]

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Structure of the human 48S initiation complex in closed state (h48S AUG closed)

Release date: May 11, 2022
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp7
Q-score: 0.337

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ DOI: doi:10.1093/nar/gkac283 Pubmed: 35489072 ]

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Structure of a human 48S translational initiation complex - 40S body

Release date: Sept. 16, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ybw
Q-score: 0.517

Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V

Science (2020) 369 pp. 1220-1227 [ DOI: doi:10.1126/science.aba4904 Pubmed: 32883864 ]

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