Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8z4e
Q-score: 0.378
Wang M, Gao Y, Shen C, Yang W, Peng Q, Cheng J, Shen HM, Yang Y, Gao GF, Shi Y
Nat Commun (2024) 15 pp. 8871-8871 [ Pubmed: 39402031 DOI: doi:10.1038/s41467-024-53301-6 ]
- Neuraminidase (42 kDa, Protein from Influenza A virus)
- Light chain of 18_14d scfv (22 kDa, Protein from Homo sapiens)
- Structure of human 18_14d c and 1g01 scfv in complex with influenza virus neuraminidase from a/yunan/dq001/2016 (h5n6) (Complex from Influenza A virus (A/Yunan/DQ001/2016 (H5N6)))
- Heavy chain of 18_14d scfv (25 kDa, Protein from Homo sapiens)
- Heavy chain of 1g01 scfv (24 kDa, Protein from Homo sapiens)
- Light chain of 1g01 scfv (23 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8gat
Q-score: 0.562
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M
Immunity (2024) 57 pp. 574-586.e7 [ Pubmed: 38430907 DOI: doi:10.1016/j.immuni.2024.02.003 ]
- Vasodilator-stimulated phosphoprotein, neuraminidase chimera (51 kDa, Protein from Influenza A virus (A/Indiana/10/2011(H3N2)))
- Fab 1g01, heavy chain (25 kDa, Protein from Homo sapiens)
- Influenza virus neuraminidase from a/indiana/10/2011 (h3n2v) in complex with fabs nds.1 and 1g01 (580 kDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 1g01, light chain (23 kDa, Protein from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8gau
Q-score: 0.449
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M
Immunity (2024) 57 pp. 574-586.e7 [ Pubmed: 38430907 DOI: doi:10.1016/j.immuni.2024.02.003 ]
- Fab nds.1, light chain (23 kDa, Protein from Homo sapiens)
- Fab nds.1, heavy chain (24 kDa, Protein from Homo sapiens)
- Vasodilator-stimulated phosphoprotein, neuraminidase chimera (51 kDa, Protein from Influenza A virus (A/Indiana/10/2011(H3N2)))
- Fab 1g01, heavy chain (25 kDa, Protein from Homo sapiens)
- Influenza virus neuraminidase from a/indiana/10/2011 (h3n2v) in complex with fabs nds.1 and 1g01 (580 kDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 1g01, light chain (23 kDa, Protein from Homo sapiens)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8gav
Q-score: 0.605
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M
Immunity (2024) 57 pp. 574-586.e7 [ Pubmed: 38430907 DOI: doi:10.1016/j.immuni.2024.02.003 ]
- Fab nds.3, heavy chain (24 kDa, Protein from Homo sapiens)
- Fab nds.3, light chain (22 kDa, Protein from Homo sapiens)
- Neuraminidase (51 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza virus neuraminidase from a/darwin/09/2021 (h3n2) in complex with fab nds.3 (380 kDa, Complex from Homo sapiens)
Structure of 3A10 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ez3
Q-score: 0.613
Lei R, Kim W, Lv H, Mou Z, Scherm MJ, Schmitz AJ, Turner JS, Tan TJC, Wang Y, Ouyang WO, Liang W, Rivera-Cardona J, Teo C, Graham CS, Brooke CB, Presti RM, Mok CKP, Krammer F, Dai X, Ellebedy AH, Wu NC
Immunity (2023) 56 pp. 2621- [ DOI: doi:10.1016/j.immuni.2023.10.005 Pubmed: 37967533 ]
- Light chain of influenza virus neuraminidase antibody 3a10 (11 kDa, Protein from Homo sapiens)
- Neuraminidase (42 kDa, Protein from Influenza A virus (A/Moscow/10/1999(H3N2)))
- Alpha-d-mannopyranose (180 Da, Ligand)
- Structure of 3a10 fab in complex with a/moscow/10/1999 (h3n2) influenza virus neuraminidase (Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of influenza virus neuraminidase antibody 3a10 (13 kDa, Protein from Homo sapiens)
Structure of 1F04 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ez7
Q-score: 0.638
Lei R, Kim W, Lv H, Mou Z, Scherm MJ, Schmitz AJ, Turner JS, Tan TJC, Wang Y, Ouyang WO, Liang W, Rivera-Cardona J, Teo C, Graham CS, Brooke CB, Presti RM, Mok CKP, Krammer F, Dai X, Ellebedy AH, Wu NC
Immunity (2023) 56 pp. 2621- [ DOI: doi:10.1016/j.immuni.2023.10.005 Pubmed: 37967533 ]
- Neuraminidase (42 kDa, Protein from Influenza A virus (A/Moscow/10/1999(H3N2)))
- Alpha-d-mannopyranose (180 Da, Ligand)
- Structure of 1f04 fab in complex with a/moscow/10/1999 (h3n2) influenza virus neuraminidase (Complex from Influenza A virus)
- Light chain of influenza virus neuraminidase antibody 1f04 (11 kDa, Protein from Homo sapiens)
- Heavy chain of influenza virus neuraminidase antibody 1f04 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of 3C08 Fab in complex with A/Moscow/10/1999 (H3N2) influenza virus neuraminidase
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8ez8
Q-score: 0.571
Lei R, Kim W, Lv H, Mou Z, Scherm MJ, Schmitz AJ, Turner JS, Tan TJC, Wang Y, Ouyang WO, Liang W, Rivera-Cardona J, Teo C, Graham CS, Brooke CB, Presti RM, Mok CKP, Krammer F, Dai X, Ellebedy AH, Wu NC
Immunity (2023) 56 pp. 2621- [ DOI: doi:10.1016/j.immuni.2023.10.005 Pubmed: 37967533 ]
- Neuraminidase (42 kDa, Protein from Influenza A virus (A/Moscow/10/1999(H3N2)))
- Heavy chain of influenza virus neuraminidase antibody 3c08 (13 kDa, Protein from Homo sapiens)
- Structure of 3c08 fab in complex with a/moscow/10/1999 (h3n2) influenza virus neuraminidase (Complex from Influenza A virus)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Light chain of influenza virus neuraminidase antibody 3c08 (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8e6j
Q-score: 0.556
Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreno-Parra JA, Jimenez-Alvarez L, Cruz-Lagunas A, Zuniga J, Mudd PA, Cox RJ, Wilson IA, Ward AB, Ellebedy AH, Krammer F
Immunity (2023) 56 pp. 1927-1938.e8 [ Pubmed: 37506693 DOI: doi:10.1016/j.immuni.2023.07.004 ]
- 3h03 fragment antigen binding heavy chain (24 kDa, Protein from Homo sapiens)
- 3h03 fab in complex with influenza virus neuraminidase from a/brevig mission/1/1918 (h1n1) (Complex from Influenza A virus (A/Brevig Mission/1/1918(H1N1)))
- 3h03 fragment antigen binding light chain (23 kDa, Protein from Homo sapiens)
- Neuraminidase (49 kDa, Protein from Influenza A virus (A/Brevig Mission/1/1918(H1N1)))
2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8e6k
Q-score: 0.512
Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreno-Parra JA, Jimenez-Alvarez L, Cruz-Lagunas A, Zuniga J, Mudd PA, Cox RJ, Wilson IA, Ward AB, Ellebedy AH, Krammer F
Immunity (2023) 56 pp. 1927-1938.e8 [ Pubmed: 37506693 DOI: doi:10.1016/j.immuni.2023.07.004 ]
- 2h08 fab in complex with influenza virus neuraminidase from a/brevig mission/1/1918 (h1n1) (Complex from Influenza A virus (A/Brevig Mission/1/1918(H1N1)))
- 2h08 fragment antigen binding light chain (23 kDa, Protein from Homo sapiens)
- Neuraminidase (49 kDa, Protein from Influenza A virus (A/Brevig Mission/1/1918(H1N1)))
- 2h08 fragment antigen binding heavy chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 6v4n
Q-score: 0.594
Madsen A, Dai YN, McMahon M, Schmitz AJ, Turner JS, Tan J, Lei T, Alsoussi WB, Strohmeier S, Amor M, Mohammed BM, Mudd PA, Simon V, Cox RJ, Fremont DH, Krammer F, Ellebedy AH
Immunity (2020) 53 pp. 852- [ Pubmed: 32976769 DOI: doi:10.1016/j.immuni.2020.08.015 ]
- Water (18 Da, Ligand)
- Influenza virus neuraminidase (Complex from Influenza B virus)
- Structure of human 1g05 fab in complex with influenza virus neuraminidase from b/phuket/3073/2013 (400 kDa, Complex)
- Antibody fab light chain (23 kDa, Protein from Homo sapiens)
- Beta-d-mannopyranose (180 Da, Ligand)
- Neuraminidase (50 kDa, Protein from Influenza B virus)
- Calcium ion (40 Da, Ligand)
- Antibody fab heavy chain (26 kDa, Protein from Homo sapiens)
- Human antibody (Complex from Homo sapiens)