Cryo-EM structure of human insulin receptor bound to 3 IGF-I
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8xjs
Q-score: 0.362
To Be Published
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
- Isoform short of insulin receptor (155 kDa, Protein from Homo sapiens)
- Complex of insulin receptor with 3 igf-i (Complex from Homo sapiens)
Cryo-EM structure of human insulin receptor bound to 4 IGF-I
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8xk1
Q-score: 0.362
To Be Published
- Complex of insulin receptor with 4 igf-i (Complex from Homo sapiens)
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
- Isoform short of insulin receptor (155 kDa, Protein from Homo sapiens)
Cryo-EM structure of human insulin receptor bound to 4 IGF-I, conformation 3
Resolution: 5.0 Å
EM Method: Single-particle
Fitted PDBs: 8xkm
Q-score: 0.149
To Be Published
- The complex of insulin receptor with 4 igf-i (Complex from Homo sapiens)
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
- Isoform short of insulin receptor (155 kDa, Protein from Homo sapiens)
Cryo-EM structure of human insulin receptor bound to 4 IGF-I, conformation 2
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8xkr
Q-score: 0.279
To Be Published
- Complex of insulin receptor with 4 igf-i (Complex from Homo sapiens)
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
- Isoform short of insulin receptor (155 kDa, Protein from Homo sapiens)
Cryo-EM structure of the IR/IGF-I complex, conformation 2
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8x2m
Q-score: 0.416
To Be Published
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
- The complex of human ir with 4 igf-i (Complex from Homo sapiens)
- Isoform short of insulin receptor (155 kDa, Protein from Homo sapiens)
Cryo-EM structure of the IR/IGF-I complex, conformation 1
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8x06
Q-score: 0.396
To Be Published
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
- Complex of ir with igf-i (Complex from Homo sapiens)
- Isoform short of insulin receptor (155 kDa, Protein from Homo sapiens)
Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation.
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8u4c
Q-score: 0.359
An W, Hall C, Li J, Hung A, Wu J, Park J, Wang L, Bai XC, Choi E
Nat Commun (2024) 15 pp. 2609-2609 [ DOI: doi:10.1038/s41467-024-46990-6 Pubmed: 38521788 ]
- Insulin receptor (156 kDa, Protein from Homo sapiens)
- Long form insulin receptor (ir-b) with four igf2 bound, symmetric conformation. (Complex from Homo sapiens)
- Insulin-like growth factor ii (20 kDa, Protein from Homo sapiens)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8u4e
Q-score: 0.279
An W, Hall C, Li J, Hung A, Wu J, Park J, Wang L, Bai XC, Choi E
Nat Commun (2024) 15 pp. 2609-2609 [ DOI: doi:10.1038/s41467-024-46990-6 Pubmed: 38521788 ]
- Insulin receptor (156 kDa, Protein from Homo sapiens)
- Long form insulin receptor (ir-b) with three igf2 bound, asymmetric conformation. (Complex from Homo sapiens)
- Insulin-like growth factor ii (20 kDa, Protein from Homo sapiens)