ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8vuw
Q-score: 0.538
Petroff JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017- [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Erwinia chrysanthemi ligand-gated ion channel (37 kDa, Protein from Dickeya chrysanthemi)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Elic5 (p254g/c300s/v261y/g319f/i320f) with cysteamine in 2:1:1 popc:pope:popg nanodisc (Complex from Dickeya chrysanthemi)
Human TRPV3 tetramer structure, closed conformation
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8gka
Q-score: 0.553
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S
Nature (2023) 621 pp. 206-214 [ DOI: doi:10.1038/s41586-023-06470-1 Pubmed: 37648856 ]
- Trpv3 ion channel- tetrameric oligomerization assembly (Complex from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 3 (90 kDa, Protein from Homo sapiens)
ELIC with cysteamine in POPC nanodisc
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d64
Q-score: 0.543
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Elic with cysteamine in popc nanodisc (Complex from Dickeya dadantii)
- Erwinia ligand-gated ion channel (35 kDa, Protein from Dickeya dadantii)
ELIC with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d66
Q-score: 0.545
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Erwinia ligand-gated ion channel (36 kDa, Protein from Dickeya dadantii)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Elic with cysteamine in 2:1:1 popc:pope:popg nanodisc (Complex from Dickeya dadantii)
ELIC3 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8d67
Q-score: 0.507
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 7cfs
Q-score: 0.483
Sun D, Liu S, Li S, Zhang M, Yang F, Wen M, Shi P, Wang T, Pan M, Chang S, Zhang X, Zhang L, Tian C, Liu L
eLife (2020) 9 [ Pubmed: 32915133 DOI: doi:10.7554/eLife.57096 ]
- Cholesterol hemisuccinate (486 Da, Ligand)
- Acid-sensing ion channel 1 (54 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hasic1a (Complex from Homo sapiens)