ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8vuw
Q-score: 0.538
Petroff JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017- [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Erwinia chrysanthemi ligand-gated ion channel (37 kDa, Protein from Dickeya chrysanthemi)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Elic5 (p254g/c300s/v261y/g319f/i320f) with cysteamine in 2:1:1 popc:pope:popg nanodisc (Complex from Dickeya chrysanthemi)
Cryo-EM structure of the wild-type AtMSL10 in GDN
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8tdj
Q-score: 0.395
Nat Commun (2023) 14 pp. 6284-6284 [ Pubmed: 37805510 DOI: doi:10.1038/s41467-023-42117-5 ]
Cryo-EM structure of AtMSL10-G556V
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tdk
Q-score: 0.353
Nat Commun (2023) 14 pp. 6284-6284 [ Pubmed: 37805510 DOI: doi:10.1038/s41467-023-42117-5 ]
Cryo-EM structure of the wild-type AtMSL10 in saposin
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tdl
Q-score: 0.404
Nat Commun (2023) 14 pp. 6284-6284 [ Pubmed: 37805510 DOI: doi:10.1038/s41467-023-42117-5 ]
Cryo-EM structure of AtMSL10-K539E
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8tdm
Q-score: 0.369
Nat Commun (2023) 14 pp. 6284-6284 [ Pubmed: 37805510 DOI: doi:10.1038/s41467-023-42117-5 ]
Human TRPV3 tetramer structure, closed conformation
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8gka
Q-score: 0.553
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S
Nature (2023) 621 pp. 206-214 [ DOI: doi:10.1038/s41586-023-06470-1 Pubmed: 37648856 ]
- Trpv3 ion channel- tetrameric oligomerization assembly (Complex from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 3 (90 kDa, Protein from Homo sapiens)
Human TRPV3 pentamer structure
Resolution: 4.38 Å
EM Method: Single-particle
Fitted PDBs: 8gkg
Q-score: 0.304
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S
Nature (2023) 621 pp. 206-214 [ DOI: doi:10.1038/s41586-023-06470-1 Pubmed: 37648856 ]
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d63
Q-score: 0.542
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
ELIC with cysteamine in POPC nanodisc
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d64
Q-score: 0.543
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Elic with cysteamine in popc nanodisc (Complex from Dickeya dadantii)
- Erwinia ligand-gated ion channel (35 kDa, Protein from Dickeya dadantii)
ELIC apo in 2:1:1 POPC:POPE:POPG nanodisc
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8d65
Q-score: 0.511
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]