Cryo-EM structure of Arabidopsis CNGC1
Wang J, Du BY, Zhang X, Qu X, Yang Y, Yang Z, Wang YF, Zhang P
Nat Plants (2025) [ Pubmed: 39979428 DOI: doi:10.1038/s41477-025-01923-z ]
- Water (18 Da, Ligand)
- Cyclic nucleotide-gated ion channel 1 (83 kDa, Protein from Arabidopsis thaliana)
- Structure of cngc1 in gdn (Complex from Arabidopsis thaliana)
- Calcium ion (40 Da, Ligand)
Curved structure of mPIEZO1-S2472E
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2025) 113 pp. 590- [ Pubmed: 39719701 DOI: doi:10.1016/j.neuron.2024.11.020 ]
- S2472e-curved structure (Complex from Mus musculus)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
Flattened structure of mPIEZO1-S2472E
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2025) 113 pp. 590- [ Pubmed: 39719701 DOI: doi:10.1016/j.neuron.2024.11.020 ]
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- S2472e-intermediate structure (Complex from Mus musculus)
Cryo-EM structure of the human TACAN channel in a closed state
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 7f6v
Q-score: 0.406
Chen X, Wang Y, Li Y, Lu X, Chen J, Li M, Wen T, Liu N, Chang S, Zhang X, Yang X, Shen Y
Cell Rep (2022) 38 pp. 110445-110445 [ Pubmed: 35235791 DOI: doi:10.1016/j.celrep.2022.110445 ]
- Ion channel tacan (40 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Cryo-em structure of the human tacan channel in a closed state (Cellular component from Homo sapiens)
Human TRPM2 ion channel in amphipol (apo state)
To Be Published
Cryo-EM structure of human TMEM120A
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7n7p
Q-score: 0.508
Xue J, Han Y, Baniasadi H, Zeng W, Pei J, Grishin NV, Wang J, Tu BP, Jiang Y
eLife (2021) 10 [ Pubmed: 34374645 DOI: doi:10.7554/eLife.71220 ]
- Ion channel tacan (42 kDa, Protein from Homo sapiens)
- Human tmem120a with coa (Complex from Homo sapiens)
- Coenzyme a (767 Da, Ligand)