ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8vuw
Q-score: 0.538
Petroff JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017- [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Erwinia chrysanthemi ligand-gated ion channel (37 kDa, Protein from Dickeya chrysanthemi)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Elic5 (p254g/c300s/v261y/g319f/i320f) with cysteamine in 2:1:1 popc:pope:popg nanodisc (Complex from Dickeya chrysanthemi)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d63
Q-score: 0.542
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
ELIC with cysteamine in POPC nanodisc
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d64
Q-score: 0.543
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Elic with cysteamine in popc nanodisc (Complex from Dickeya dadantii)
- Erwinia ligand-gated ion channel (35 kDa, Protein from Dickeya dadantii)
ELIC apo in 2:1:1 POPC:POPE:POPG nanodisc
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8d65
Q-score: 0.511
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
ELIC with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8d66
Q-score: 0.545
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
- 2-amino-ethanethiol (77 Da, Ligand)
- Erwinia ligand-gated ion channel (36 kDa, Protein from Dickeya dadantii)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Elic with cysteamine in 2:1:1 popc:pope:popg nanodisc (Complex from Dickeya dadantii)
ELIC3 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8d67
Q-score: 0.507
Petroff II JT, Dietzen NM, Santiago-McRae E, Deng B, Washington MS, Chen LJ, Trent Moreland K, Deng Z, Rau M, Fitzpatrick JAJ, Yuan P, Joseph TT, Henin J, Brannigan G, Cheng WWL
Nat Commun (2022) 13 pp. 7017-7017 [ Pubmed: 36385237 DOI: doi:10.1038/s41467-022-34813-5 ]
Cryo-EM structure of Arabidopsis thaliana MSL1
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 6vxm
Q-score: 0.513
Deng Z, Maksaev G, Schlegel AM, Zhang J, Rau M, Fitzpatrick JAJ, Haswell ES, Yuan P
Nat Commun (2020) 11 pp. 3690-3690 [ Pubmed: 32704140 DOI: doi:10.1038/s41467-020-17538-1 ]
- Msl1 (Complex from Arabidopsis thaliana)
- Eicosane (282 Da, Ligand)
- Mechanosensitive ion channel protein 1, mitochondrial (46 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of Arabidopsis thaliana MSL1 A320V
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 6vxn
Q-score: 0.478
Deng Z, Maksaev G, Schlegel AM, Zhang J, Rau M, Fitzpatrick JAJ, Haswell ES, Yuan P
Nat Commun (2020) 11 pp. 3690-3690 [ Pubmed: 32704140 DOI: doi:10.1038/s41467-020-17538-1 ]
- Mechanosensitive ion channel protein 1, mitochondrial (46 kDa, Protein from Arabidopsis thaliana)
- Msl1 a320v (Complex from Arabidopsis thaliana)
- Dodecane (170 Da, Ligand)
Cryo-EM structure of Arabidopsis thaliana MSL1 in lipid nanodisc
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 6vxp
Q-score: 0.42
Deng Z, Maksaev G, Schlegel AM, Zhang J, Rau M, Fitzpatrick JAJ, Haswell ES, Yuan P
Nat Commun (2020) 11 pp. 3690-3690 [ Pubmed: 32704140 DOI: doi:10.1038/s41467-020-17538-1 ]