Human TRPV3 tetramer structure, closed conformation
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8gka
Q-score: 0.553
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S
Nature (2023) 621 pp. 206-214 [ DOI: doi:10.1038/s41586-023-06470-1 Pubmed: 37648856 ]
- Trpv3 ion channel- tetrameric oligomerization assembly (Complex from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 3 (90 kDa, Protein from Homo sapiens)
Human TRPV3 pentamer structure
Resolution: 4.38 Å
EM Method: Single-particle
Fitted PDBs: 8gkg
Q-score: 0.304
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S
Nature (2023) 621 pp. 206-214 [ DOI: doi:10.1038/s41586-023-06470-1 Pubmed: 37648856 ]
the Curved Structure of mPIEZO1 in Lipid Bilayer
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 7wlt
Q-score: 0.462
Yang X, Lin C, Chen X, Li S, Li X, Xiao B
Nature (2022) 604 pp. 377-383 [ DOI: doi:10.1038/s41586-022-04574-8 Pubmed: 35388220 ]
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- The curved structure of mpiezo1 in lipid bilayer (Complex from Mus musculus)
the Curved Structure of mPIEZO1 in Lipid Bilayer
Resolution: 6.81 Å
EM Method: Single-particle
Fitted PDBs: 7wlu
Q-score: 0.196
Yang X, Lin C, Chen X, Li S, Li X, Xiao B
Nature (2022) 604 pp. 377-383 [ DOI: doi:10.1038/s41586-022-04574-8 Pubmed: 35388220 ]
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- The flattened structure of mpiezo1 in lipid bilayer (Complex from Mus musculus)
Cryo-EM Structure of the Mammalian Tactile Channel Piezo2
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6kg7
Q-score: 0.437
Wang L, Zhou H, Zhang M, Liu W, Deng T, Zhao Q, Li Y, Lei J, Li X, Xiao B
Nature (2019) 573 pp. 225-229 [ DOI: doi:10.1038/s41586-019-1505-8 Pubmed: 31435011 ]
- Homo-trimer of piezo2 (1 MDa, Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 2 (325 kDa, Protein from Mus musculus)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6drj
Q-score: 0.455
Huang Y, Winkler PA, Sun W, Lu W, Du J
Nature (2018) 562 pp. 145-149 [ Pubmed: 30250252 DOI: doi:10.1038/s41586-018-0558-4 ]
- Ion channel 1 (500 kDa, Complex from Danio rerio)
- Transient receptor potential cation channel, subfamily m, member 2 (168 kDa, Protein from Danio rerio)
- Calcium ion (40 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6drk
Q-score: 0.35
Huang Y, Winkler PA, Sun W, Lu W, Du J
Nature (2018) 562 pp. 145-149 [ Pubmed: 30250252 DOI: doi:10.1038/s41586-018-0558-4 ]
- Ion channel 1 (500 kDa, Complex from Danio rerio)
- Transient receptor potential cation channel, subfamily m, member 2 (168 kDa, Protein from Danio rerio)
Structure of an acid sensing ion channel in a resting state at high pH
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6ave
Q-score: 0.393
Nature (2018) 555 pp. 397-401 [ Pubmed: 29513651 DOI: doi:10.1038/nature25782 ]
- Acid sensing ion channel 1a (180 kDa, Complex from Gallus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Acid-sensing ion channel 1 (60 kDa, Protein from Gallus gallus)
Structure of the mechanically activated ion channel Piezo1
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6bpz
Q-score: 0.357
Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB
Nature (2018) 554 pp. 481-486 [ DOI: doi:10.1038/nature25453 Pubmed: 29261642 ]
- Piezo-type mechanosensitive ion channel component 1,piezo-type mechanosensitive ion channel component 1,mouse piezo1,piezo-type mechanosensitive ion channel component 1,piezo-type mechanosensitive ion channel component 1 (161 kDa, Protein from Mus musculus)
- Mouse piezo1 (876 kDa, Complex from Mus musculus)