Alvinella pompejana nicotinic acetylcholine receptor Alpo in apo state (dataset 2)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8bxb
Q-score: 0.4
De Gieter S, Gallagher C, Wijckmans E, Pasini D, Ulens C, Efremov RG
eLife (2023) 12 [ DOI: doi:10.7554/eLife.86029 Pubmed: 37395731 ]
- Water (18 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pentameric ligand-gated ion channel (270 kDa, Complex from Alvinella pompejana)
- Acetylcholine receptor (54 kDa, Protein from Alvinella pompejana)
cryo-EM structure of hSlo1 in plasma membrane vesicles
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8ghf
Q-score: 0.572
PNAS (2023) 120 pp. e2302325120-e2302325120 [ DOI: doi:10.1073/pnas.2302325120 Pubmed: 37098056 ]
- Magnesium ion (24 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Calcium-activated potassium channel subunit alpha-1 (122 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Alfa-hslo1-egfp ion channel (Complex from Homo sapiens)
Composite Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7n5d
Q-score: 0.489
Jojoa-Cruz S, Saotome K, Tsui CCA, Lee WH, Sansom MSP, Murthy SE, Patapoutian A, Ward AB
Nat Commun (2022) 13 pp. 850-850 [ DOI: doi:10.1038/s41467-022-28511-5 Pubmed: 35165281 ]
- Flyc1 (607 kDa, Cellular component from Dionaea muscipula)
- Mechanosensitive ion channel flycatcher1 (86 kDa, Protein from Dionaea muscipula)
- Palmitic acid (256 Da, Ligand)
Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7n5e
Q-score: 0.453
Jojoa-Cruz S, Saotome K, Tsui CCA, Lee WH, Sansom MSP, Murthy SE, Patapoutian A, Ward AB
Nat Commun (2022) 13 pp. 850-850 [ DOI: doi:10.1038/s41467-022-28511-5 Pubmed: 35165281 ]
- Flyc1 (607 kDa, Cellular component from Dionaea muscipula)
- Mechanosensitive ion channel flycatcher1 (86 kDa, Protein from Dionaea muscipula)
- Palmitic acid (256 Da, Ligand)
Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7n5f
Q-score: 0.44
Jojoa-Cruz S, Saotome K, Tsui CCA, Lee WH, Sansom MSP, Murthy SE, Patapoutian A, Ward AB
Nat Commun (2022) 13 pp. 850-850 [ DOI: doi:10.1038/s41467-022-28511-5 Pubmed: 35165281 ]
- Flyc1 (607 kDa, Cellular component from Dionaea muscipula)
- Mechanosensitive ion channel flycatcher1 (86 kDa, Protein from Dionaea muscipula)
- Palmitic acid (256 Da, Ligand)
Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Up' conformation in GDN
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7n5g
Q-score: 0.496
Jojoa-Cruz S, Saotome K, Tsui CCA, Lee WH, Sansom MSP, Murthy SE, Patapoutian A, Ward AB
Nat Commun (2022) 13 pp. 850-850 [ DOI: doi:10.1038/s41467-022-28511-5 Pubmed: 35165281 ]
- Flyc1 (607 kDa, Cellular component from Dionaea muscipula)
- Mechanosensitive ion channel flycatcher1 (86 kDa, Protein from Dionaea muscipula)
- Palmitic acid (256 Da, Ligand)
Cryo-EM structure of TACAN in the H196A H197A mutant form (TMEM120A)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7n0l
Q-score: 0.573
Niu Y, Tao X, Vaisey G, Olinares PDB, Alwaseem H, Chait BT, MacKinnon R
eLife (2021) 10 [ Pubmed: 34374644 DOI: doi:10.7554/eLife.71188 ]
- Homo-dimeric assembly of h196a h197a mutant tacan(tmem120a) (Complex from Mus musculus)
- Coenzyme a (767 Da, Ligand)
- Ion channel tacan (40 kDa, Protein from Mus musculus)
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 6vtk
Q-score: 0.554
eLife (2020) 9 [ DOI: doi:10.7554/eLife.56527 Pubmed: 32496192 ]
- Acid-sensing ion channel (180 kDa, Complex from Gallus gallus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Acid-sensing ion channel 1 (60 kDa, Protein from Gallus gallus)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 6vtl
Q-score: 0.411
eLife (2020) 9 [ DOI: doi:10.7554/eLife.56527 Pubmed: 32496192 ]
- Acid-sensing ion channel (180 kDa, Complex from Gallus gallus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Acid-sensing ion channel 1 (60 kDa, Protein from Gallus gallus)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6gyo
Q-score: 0.502
Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP
To Be Published
- 1,2-diacyl-sn-glycero-3-phosphoinositol (836 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (60 kDa, Protein from Homo sapiens)
- Adenosine-3',5'-cyclic-monophosphate (329 Da, Ligand)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 4 (Cellular component from Homo sapiens)
- Unknown atom or ion (65 Da, Ligand)