P301L tau filaments from human brain
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
P301T type I tau filaments from human brain
Resolution: 2.26 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gg1
Q-score: 0.69
Schweighauser M, Shi Y, Murzin AG, Garringer HJ, Vidal R, Murrell JR, Erro ME, Seelaar H, Ferrer I, van Swieten JC, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.15.608062 Pubmed: 39185206 ]
CTE type II (tau intermediate amyloid)
Resolution: 3.35 Å
EM Method: Helical reconstruction
Fitted PDBs: 8qjj
Q-score: 0.484
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Resolution: 2.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q2l
Q-score: 0.667
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Tau - AD-LIA4 (tau intermediate amyloid)
Resolution: 3.81 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q8e
Q-score: 0.258
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Tau - AD-LIA5 (tau intermediate amyloid)
Resolution: 2.93 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q8f
Q-score: 0.568
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Tau - AD-LIA7 (tau intermediate amyloid)
Resolution: 3.04 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q8l
Q-score: 0.538
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Resolution: 2.95 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q8m
Q-score: 0.587
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Resolution: 2.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q8r
Q-score: 0.684
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)
Resolution: 2.68 Å
EM Method: Helical reconstruction
Fitted PDBs: 8q8s
Q-score: 0.583
Lovestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW
Nature (2024) 625 pp. 119-125 [ Pubmed: 38030728 DOI: doi:10.1038/s41586-023-06788-w ]
- Isoform tau-d of microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Amyloid (Complex from Homo sapiens)