Cryo-EM structure of MRV full core
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9cyx
Q-score: 0.535
Liu X, Xia X, Martynowycz MW, Gonen T, Zhou ZH
Nat Commun (2024) 15 pp. 10638-10638 [ DOI: doi:10.1038/s41467-024-54968-7 Pubmed: 39639006 ]
- Inner capsid protein sigma-2 (47 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Mammalian orthoreovirus 3 dearing (Virus from Mammalian orthoreovirus 3 Dearing)
- Outer capsid protein lambda-2 (143 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Lambda 1 (141 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
Cryo-EM structure of MRV virion
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9cyy
Q-score: 0.586
Liu X, Xia X, Martynowycz MW, Gonen T, Zhou ZH
Nat Commun (2024) 15 pp. 10638-10638 [ Pubmed: 39639006 DOI: doi:10.1038/s41467-024-54968-7 ]
- Mammalian orthoreovirus 3 dearing (Virus from Mammalian orthoreovirus 3 Dearing)
- Rna-directed rna polymerase (142 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Outer capsid protein sigma-3 (41 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Inner capsid protein sigma-2 (47 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Outer capsid protein lambda-2 (144 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Outer capsid protein mu-1 (76 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Mu2 (83 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
- Lambda 1 (141 kDa, Protein from Mammalian orthoreovirus 3 Dearing)
SpRY-Cas9:gRNA complex targeting TGG PAM DNA
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8spq
Q-score: 0.431
Hibshman GN, Bravo JPK, Hooper MM, Dangerfield TL, Zhang H, Finkelstein IJ, Johnson KA, Taylor DW
Nat Commun (2024) 15 pp. 3663-3663 [ Pubmed: 38688943 DOI: doi:10.1038/s41467-024-47830-3 ]
- Grna (31 kDa, RNA from Streptococcus pyogenes)
- Ternary complex of spry-cas9 with lambda 1 grna and lambda 1 dna (211 kDa, Complex from Streptococcus pyogenes)
- Ts (5 kDa, DNA from Escherichia phage Lambda)
- Nts (5 kDa, DNA from Escherichia phage Lambda)
- Magnesium ion (24 Da, Ligand)
- Ts (16 kDa, DNA from Escherichia phage Lambda)
- Crispr-associated endonuclease cas9/csn1 (159 kDa, Protein from Streptococcus pyogenes serotype M1)
SpRY-Cas9:gRNA complex targeting TTC PAM DNA
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 8sqh
Q-score: 0.379
Hibshman GN, Bravo JPK, Hooper MM, Dangerfield TL, Zhang H, Finkelstein IJ, Johnson KA, Taylor DW
Nat Commun (2024) 15 pp. 3663-3663 [ Pubmed: 38688943 DOI: doi:10.1038/s41467-024-47830-3 ]
- Grna (31 kDa, RNA from Streptococcus pyogenes)
- Ts (5 kDa, DNA from Escherichia phage Lambda)
- Nts (16 kDa, DNA from Escherichia phage Lambda)
- Magnesium ion (24 Da, Ligand)
- Crispr-associated endonuclease cas9/csn1 (159 kDa, Protein from Streptococcus pyogenes)
- Ternary complex of spry-cas9 with lambda 1 grna and lambda 1 dna oligo (211 kDa, Complex from Streptococcus pyogenes)
- Ts (4 kDa, DNA from Escherichia phage Lambda)
SpRY-Cas9:gRNA complex targeting TAC PAM DNA
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8srs
Q-score: 0.521
Hibshman GN, Bravo JPK, Hooper MM, Dangerfield TL, Zhang H, Finkelstein IJ, Johnson KA, Taylor DW
Nat Commun (2024) 15 pp. 3663-3663 [ Pubmed: 38688943 DOI: doi:10.1038/s41467-024-47830-3 ]
- Water (18 Da, Ligand)
- Grna (31 kDa, RNA from Streptococcus pyogenes)
- Ternary complex of spry-cas9 with lambda 1 grna and lambda 1 dna (211 kDa, Complex from Streptococcus pyogenes)
- Ts (5 kDa, DNA from Escherichia phage Lambda)
- Magnesium ion (24 Da, Ligand)
- Nts (16 kDa, DNA from Escherichia phage Lambda)
- Crispr-associated endonuclease cas9/csn1 (159 kDa, Protein from Streptococcus pyogenes)
- Ts (3 kDa, DNA from Escherichia phage Lambda)
Cryo-EM Structure of PG9RSH DU011 Fab in complex with BG505 DS-SOSIP.664
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8fk5
Q-score: 0.456
Holt GT, Gorman J, Wang S, Lowegard AU, Zhang B, Liu T, Lin BC, Louder MK, Frenkel MS, McKee K, O'Dell S, Rawi R, Shen CH, Doria-Rose NA, Kwong PD, Donald BR
Cell Rep (2023) 42 pp. 112711-112711 [ Pubmed: 37436900 DOI: doi:10.1016/j.celrep.2023.112711 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Immunoglobulin lambda-1 light chain-like (22 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Cryo-em structure of pg9rsh du011 fab in complex with bg505 ds-sosip.664 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoblobulin g1 fab heavy chain variable region (fragment) (27 kDa, Protein from Homo sapiens)
Mammalian orthoreovirus T3SA- in complex with the neural receptor NgR1
Sutherland DM, Strebl M, Koehler M, Welsh OL, Yu X, Hu L, Dos Santos Natividade R, Knowlton JJ, Taylor GM, Moreno RA, Worz P, Lonergan ZR, Aravamudhan P, Guzman-Cardozo C, Kour S, Pandey UB, Alsteens D, Wang Z, Prasad BVV, Stehle T, Dermody TS
PNAS (2023) 120 pp. e2219404120-e2219404120 [ DOI: doi:10.1073/pnas.2219404120 Pubmed: 37276413 ]
- T3sa- reovirus inner capsid protein lambda1 (Protein from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus inner capsid protein sigma2 (Protein from Mammalian orthoreovirus 3 Dearing)
- Nogo receptor 1 (Protein from Homo sapiens)
- Nogo receptor 1 (Complex from Homo sapiens)
- Mammalian orthoreovirus t3sa- in complex with the neural receptor ngr1 (Complex)
- T3sa- reovirus outer capsid protein mu1 (Protein from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus outer capsid protein lambda2 (Protein from Mammalian orthoreovirus 3 Dearing)
- Mammalian orthoreovirus t3sa- in complex (Complex from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus outer capsid protein sigma3 (Protein from Mammalian orthoreovirus 3 Dearing)
Sutherland DM, Strebl M, Koehler M, Welsh OL, Yu X, Hu L, Dos Santos Natividade R, Knowlton JJ, Taylor GM, Moreno RA, Worz P, Lonergan ZR, Aravamudhan P, Guzman-Cardozo C, Kour S, Pandey UB, Alsteens D, Wang Z, Prasad BVV, Stehle T, Dermody TS
PNAS (2023) 120 pp. e2219404120-e2219404120 [ DOI: doi:10.1073/pnas.2219404120 Pubmed: 37276413 ]
- T3sa- reovirus outer capsid protein sigma3 (Protein from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus outer capsid protein lambda2 (Protein from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus inner capsid protein lambda1 (Protein from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus outer capsid protein mu1 (Protein from Mammalian orthoreovirus 3 Dearing)
- Mammalian orthoreovirus 3 dearing (Virus from Mammalian orthoreovirus 3 Dearing)
- T3sa- reovirus inner capsid protein sigma2 (Protein from Mammalian orthoreovirus 3 Dearing)
AL amyloid fibril from a lambda 1 light chain
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nsl
Q-score: 0.523
Radamaker L, Karimi-Farsijani S, Andreotti G, Baur J, Neumann M, Schreiner S, Berghaus N, Motika R, Haupt C, Walther P, Schmidt V, Huhn S, Hegenbart U, Schonland SO, Wiese S, Read C, Schmidt M, Fandrich M
Nat Commun (2021) 12 pp. 6434-6434 [ DOI: doi:10.1038/s41467-021-26553-9 Pubmed: 34741031 ]
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7elh
Q-score: 0.478
Pan M, Alvarez-Cabrera AL, Kang JS, Wang L, Fan C, Zhou ZH
Nat Commun (2021) 12 pp. 4176-4176 [ DOI: doi:10.1038/s41467-021-24455-4 Pubmed: 34234134 ]
- Lambda 1 (122 kDa, Protein from Mammalian orthoreovirus 3)
- Mammalian orthoreovirus 3 dearing (Virus from Mammalian orthoreovirus 3 Dearing)
- Rna (60-mer) (19 kDa, RNA from Mammalian orthoreovirus 3 Dearing)
- Rna-directed rna polymerase (142 kDa, Protein from Mammalian orthoreovirus 3)
- Minor core protein mu2 (83 kDa, Protein from Mammalian orthoreovirus 3)
- Transcript rna (1 kDa, RNA from Mammalian orthoreovirus 3 Dearing)
- Phosphate ion (94 Da, Ligand)
- Lambda 1 (19 kDa, Protein from Mammalian orthoreovirus 3)