Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8z4e
Q-score: 0.378
Wang M, Gao Y, Shen C, Yang W, Peng Q, Cheng J, Shen HM, Yang Y, Gao GF, Shi Y
Nat Commun (2024) 15 pp. 8871-8871 [ Pubmed: 39402031 DOI: doi:10.1038/s41467-024-53301-6 ]
- Neuraminidase (42 kDa, Protein from Influenza A virus)
- Light chain of 18_14d scfv (22 kDa, Protein from Homo sapiens)
- Structure of human 18_14d c and 1g01 scfv in complex with influenza virus neuraminidase from a/yunan/dq001/2016 (h5n6) (Complex from Influenza A virus (A/Yunan/DQ001/2016 (H5N6)))
- Heavy chain of 18_14d scfv (25 kDa, Protein from Homo sapiens)
- Heavy chain of 1g01 scfv (24 kDa, Protein from Homo sapiens)
- Light chain of 1g01 scfv (23 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
CryoEM structure of sNS1 complexed with Fab 4F10
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8jqm
Q-score: 0.624
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- The complex of zikv ns1 with antibody 4f10 (Complex)
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- 4f10 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Antibody 4f10 (Complex from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
- 4f10 fab light chain (11 kDa, Protein from Homo sapiens)
Structure of interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jqt
Q-score: 0.555
Yin H, Li L, Feng X, Wang Z, Zheng M, Zhao J, Fan X, Wu W, Gao L, Zhan Y, Zhao M, Lu Q
Signal Transduct Target Ther (2024) 9 pp. 323-323 [ DOI: doi:10.1038/s41392-024-02017-6 Pubmed: 39551768 ]
- Cytokine receptor common subunit gamma (28 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- 2d4-light chain (23 kDa, Protein from Homo sapiens)
- Interleukin receptor common gamma chain (il2rgamma/cd132) in complex with 2d4 (Complex from Homo sapiens)
- 2d4-heavy chain (23 kDa, Protein from Homo sapiens)
CryoEM structure of sNS1 complexed with Fab 3G2
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8jkf
Q-score: 0.581
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- The light chain of antibody 3g2 (11 kDa, Protein from Homo sapiens)
- Antibody 3g2 (Complex from Homo sapiens)
- The complex of zikv ns1 with antibody 3g2 (Complex)
- The heavy chain of antibody 3g2 (12 kDa, Protein from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
- Ns1 (40 kDa, Protein from Zika virus)
CryoEM structure of sNS1 complexed with Fab 2E11
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8jqn
Q-score: 0.605
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- Antibody 2e11 (Complex from Homo sapiens)
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- 2e11 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
- 2e11 fab light chain (11 kDa, Protein from Homo sapiens)
- The complex of zikv ns1 with antibody 2e11 (Complex)
CryoEM structure of sNS1 complexed with Fab 4B8
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8jkh
Q-score: 0.569
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- Antibody 4b8 (Complex from Homo sapiens)
- The light chain of antibody 4b8 (11 kDa, Protein from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
- The heavy chain of antibody 4b8 (12 kDa, Protein from Homo sapiens)
- Ns1 (40 kDa, Protein from Zika virus)
- The complex of zikv ns1 with antibody 4b8 (Complex)
CryoEM structure of sNS1 complexed with Fab 14G5
Resolution: 2.63 Å
EM Method: Single-particle
Fitted PDBs: 8jqs
Q-score: 0.569
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Antibody 14g5 (Complex from Homo sapiens)
- The complex of zikv ns1 with antibody 14g5 (Complex)
- 14g5 fab light chain (11 kDa, Protein from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
- 14g5 fab heavy chain (12 kDa, Protein from Homo sapiens)
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8wpw
Q-score: 0.542
Su C, He JH, Qi JX, Yang MS, Wang QH, Gao GF
To Be Published
- Cb6 fab mutant heavy chain (24 kDa, Protein from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S309 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab (Complex from Severe acute respiratory syndrome-related coronavirus)
- Cb6 fab mutant light chain (23 kDa, Protein from Homo sapiens)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 xbb.1.5 receptor-binding domain (rbd) complexed with cb6 mutant,s309, and s304 antibodies (Complex from Homo sapiens)
- Sars-cov-2 xbb.1.5 rbd (Complex)
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8wpy
Q-score: 0.488
Su C, He JH, Qi JX, Yang MS, Wang QH, Gao GF
To Be Published
- Cb6 fab mutant heavy chain (24 kDa, Protein from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S309 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Fab (Complex from Severe acute respiratory syndrome-related coronavirus)
- Cb6 fab mutant light chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 receptor-binding domain (rbd) complexed with cb6 mutant,s309, and s304 antibodies (Complex from Homo sapiens)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 rbd (Complex)
The cryoEM structure of H5N1 HA split from symmetric filament in conformation A
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8zdw
Q-score: 0.427
Li R, Gao J, Wang L, Gui M, Xiang Y
To Be Published
- H5n1 ha (Complex)
- H5m9 fab, light chain (23 kDa, Protein from Mus musculus)
- Hemagglutinin (26 kDa, Protein from Influenza A virus (strain A/Vietnam/1203/2004 H5N1))
- Split trimer of h5n1 ha-fabh5m9 complex from symmetric filament (200 kDa, Complex from Influenza A virus (strain A/Vietnam/1203/2004 H5N1))
- Hemagglutinin (38 kDa, Protein from Influenza A virus (strain A/Vietnam/1203/2004 H5N1))
- Fabh5m9 (Complex from Mus musculus)
- Anti-h5n1 hemagglutinin monoclonal anitbody h5m9 heavy chain (23 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)