SFTSV Gn in complex with JK-8/12 Fab
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8zhq
Q-score: 0.505
Zhang S, Shang H, Han S, Li J, Peng X, Wu Y, Yang X, Leng Y, Wang F, Cui N, Xu L, Zhang H, Guo Y, Xu X, Zhang N, Liu W, Li H
Ebiomedicine (2024) 111 pp. 105481-105481 [ Pubmed: 39644769 DOI: doi:10.1016/j.ebiom.2024.105481 ]
- Envelopment polyprotein (38 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Jk-8 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Jk-8 fab light chain (23 kDa, Protein from Homo sapiens)
- Jk-12 fab light chain (22 kDa, Protein from Homo sapiens)
- Jk-12 fab heavy chain (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ternary complex of sftsv gn with neutralizing antibodies fab jk-8 and jk-12 (150 kDa, Complex from Homo sapiens)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 7x35
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
Cryo-EM structure of inactive FZD1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8j9o
Q-score: 0.347
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ DOI: doi:10.1038/s41421-023-00627-y Pubmed: 38182578 ]
- Frizzled-1,soluble cytochrome b562 (75 kDa, Protein from Homo sapiens)
- Anti-bril fab light chain (24 kDa, Protein from Mus)
- Frizzled-1 with icl3-bril complex with anti-bril fab (Complex from Homo sapiens)
- Anti-bril fab heavy chain (28 kDa, Protein from Mus)
- Anti-fab nanobody (13 kDa, Protein from Vicugna pacos)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8jh7
Q-score: 0.354
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ DOI: doi:10.1038/s41421-023-00627-y Pubmed: 38182578 ]
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Complex of human fzd6 in inactivate state with accessory proteins. (Complex from Homo sapiens)
- Anti-bril fab heavy chain (25 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (14 kDa, Protein from synthetic construct)
- Frizzled-6,soluble cytochrome b562 (73 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8jhc
Q-score: 0.387
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ DOI: doi:10.1038/s41421-023-00627-y Pubmed: 38182578 ]
- Complex of fzd3 with anti-bril fab and anti-fab nanobody (Complex from Homo sapiens)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (25 kDa, Protein from Homo sapiens)
- Frizzled-3,soluble cytochrome b562 (74 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (14 kDa, Protein from synthetic construct)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 7x3y
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- 9a3 heavy chain (13 kDa, Protein from Mus musculus)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 9a3 (cvb1-e:9a3) (Complex from Coxsackievirus B1)
- 9a3 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 2E6 (CVB1-E:2E6)
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7x2g
Q-score: 0.515
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 2e6 (cvb1-e:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 2E6 (CVB1-pre-A:2E6)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 7x2i
Q-score: 0.537
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 pre-a particle in complex with nab 2e6 (cvb1-pre-a:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 2E6 (CVB1-M:2E6)
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 7x2o
Q-score: 0.591
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 mature virion in complex with nab 2e6 (cvb1-m:2e6) (Complex from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)