Canine parvovirus subtype 2a empty capsid in complex with Fab fragments of Mab 3G6
Adu OF, Lee H, Fruh SP, Schoenle MV, Weichert WS, Flyak AI, Hafenstein SL, Parrish CR
PNAS (2025) 122 pp. e2423460122-e2423460122 [ Pubmed: 39951487 DOI: doi:10.1073/pnas.2423460122 ]
- Light chain antibody fragment (11 kDa, Protein from Canis lupus familiaris)
- Capsid protein 2 (61 kDa, Protein from Canine parvovirus 2a)
- Heavy chain antibody fragment (13 kDa, Protein from Canis lupus familiaris)
- Canine parvovirus 2a (Virus from Canine parvovirus 2a)
Canine parvovirus subtype 2a empty capsid in complex with Fab fragments of Mab 2C5
Adu OF, Lee H, Fruh SP, Schoenle MV, Weichert WS, Flyak AI, Hafenstein SL, Parrish CR
PNAS (2025) 122 pp. e2423460122-e2423460122 [ Pubmed: 39951487 DOI: doi:10.1073/pnas.2423460122 ]
- Capsid protein 2 (61 kDa, Protein from Canine parvovirus 2a)
- Light chain antibody fragment (11 kDa, Protein from Canis lupus familiaris)
- Heavy chain antibody fragment (13 kDa, Protein from Canis lupus familiaris)
- Canine parvovirus 2a (Virus from Canine parvovirus 2a)
CPV2a capsid complexed with scFv2
Adu OF, Lee H, Fruh SP, Schoenle MV, Weichert WS, Flyak AI, Hafenstein SL, Parrish CR
PNAS (2025) 122 pp. e2423460122-e2423460122 [ Pubmed: 39951487 DOI: doi:10.1073/pnas.2423460122 ]
- Light-chain of scfv clone 2 (11 kDa, Protein from Canis lupus familiaris)
- Capsid protein (64 kDa, Protein from Canine parvovirus 2b)
- Canine parvovirus 2a (Virus from Canine parvovirus 2a)
- Heavy-chain of scfv clone 2 (14 kDa, Protein from Canis lupus familiaris)
CPV2a capsid complexed with scFv1
Adu OF, Lee H, Fruh SP, Schoenle MV, Weichert WS, Flyak AI, Hafenstein SL, Parrish CR
PNAS (2025) 122 pp. e2423460122-e2423460122 [ Pubmed: 39951487 DOI: doi:10.1073/pnas.2423460122 ]
- Heavy-chain of scfv clone 1 (14 kDa, Protein from Canis lupus familiaris)
- Light-chain of scfv clone 1 (11 kDa, Protein from Canis lupus familiaris)
- Capsid protein (64 kDa, Protein from Canine parvovirus 2b)
- Canine parvovirus 2a (Virus from Canine parvovirus 2a)
SFTSV Gn in complex with JK-8/12 Fab
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8zhq
Q-score: 0.505
Zhang S, Shang H, Han S, Li J, Peng X, Wu Y, Yang X, Leng Y, Wang F, Cui N, Xu L, Zhang H, Guo Y, Xu X, Zhang N, Liu W, Li H
Ebiomedicine (2024) 111 pp. 105481-105481 [ Pubmed: 39644769 DOI: doi:10.1016/j.ebiom.2024.105481 ]
- Envelopment polyprotein (38 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Jk-8 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Jk-8 fab light chain (23 kDa, Protein from Homo sapiens)
- Jk-12 fab light chain (22 kDa, Protein from Homo sapiens)
- Jk-12 fab heavy chain (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ternary complex of sftsv gn with neutralizing antibodies fab jk-8 and jk-12 (150 kDa, Complex from Homo sapiens)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 7x35
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8vqy
Q-score: 0.557
Chojnacka W, Teng J, Kim JJ, Jensen AA, Hibbs RE
Nat Commun (2024) 15 pp. 5244-5244 [ DOI: doi:10.1038/s41467-024-49471-y Pubmed: 38898000 ]
- Gamma-aminobutyric acid receptor subunit beta-2 (41 kDa, Protein from Homo sapiens)
- O-[(r)-[(2s)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-d-serine (764 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit gamma-2 (47 kDa, Protein from Homo sapiens)
- Igg2b fab heavy chain (49 kDa, Protein from Mus musculus)
- Phosphatidylethanolamine (734 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit alpha-1 (41 kDa, Protein from Homo sapiens)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Human gabaa receptor alpha1-beta2-gamma2 subtype in complex with gaba plus methaqualone (368 kDa, Complex from Homo sapiens)
- 2-methyl-3-(2-methylphenyl)quinazolin-4(3h)-one (250 Da, Ligand)
- Kappa fab light chain (23 kDa, Protein from Mus musculus)
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 8vrn
Q-score: 0.618
Chojnacka W, Teng J, Kim JJ, Jensen AA, Hibbs RE
Nat Commun (2024) 15 pp. 5244-5244 [ DOI: doi:10.1038/s41467-024-49471-y Pubmed: 38898000 ]
- Gamma-aminobutyric acid receptor subunit beta-2 (41 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- 3-(4-methylphenyl)-2-phenylquinazolin-4(3h)-one (312 Da, Ligand)
- O-[(r)-[(2s)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-d-serine (764 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit gamma-2 (47 kDa, Protein from Homo sapiens)
- Igg2b fab heavy chain (49 kDa, Protein from Mus musculus)
- Phosphatidylethanolamine (734 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit alpha-1 (41 kDa, Protein from Homo sapiens)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Human gabaa receptor alpha1-beta2-gamma2 subtype in complex with gaba plus pptq (368 kDa, Complex from Homo sapiens)
- Kappa fab light chain (23 kDa, Protein from Mus musculus)
SARS-CoV-2 Omicron Variant Spike Trimer in complex with three 17T2 Fabs
de Campos-Mata L, Trinite B, Modrego A, Tejedor Vaquero S, Pradenas E, Pons-Grifols A, Rodrigo Melero N, Carlero D, Marfil S, Santiago C, Raich-Regue D, Bueno-Carrasco MT, Tarres-Freixas F, Abanco F, Urrea V, Izquierdo-Useros N, Riveira-Munoz E, Ballana E, Perez M, Vergara-Alert J, Segales J, Carolis C, Arranz R, Blanco J, Magri G
Nat Commun (2024) 15 pp. 1051-1051 [ DOI: doi:10.1038/s41467-024-45171-9 Pubmed: 38316751 ]
- 17t2 fab (Complex from Homo sapiens)
- Spike glycoprotein (Protein from Severe acute respiratory syndrome coronavirus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- 17t2 fab heavy chain (Protein from Homo sapiens)
- 17t2 fab light chain (Protein from Homo sapiens)
- Sars-cov-2 omicron variant spike trimer in complex with three 17t2 fabs (Complex)