Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ygs
Q-score: 0.444
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13 heavy chain (12 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13 light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Locally refined region of SARS-CoV-2 spike in complex with antibodies 9G11 and 3E2.
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 9lae
Q-score: 0.522
Jiang W, Jiang Y, Sun H, Deng T, Yu K, Fang Q, Ge H, Lan M, Lin Y, Fang Z, Zhang Y, Zhou L, Li T, Yu H, Zheng Q, Li S, Xia N, Gu Y
Emerg Microbes Infect (2024) 13 pp. 2406300- [ DOI: doi:10.1038/s41467-023-39265-z Pubmed: 39470577 ]
- Heavy chain of 9g11 (13 kDa, Protein from Mus musculus)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- The fab of 3e2 (Complex from Mus musculus)
- Light chain of 9g11 (11 kDa, Protein from Mus musculus)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Sars-cov-2 spike in complex with antibodies 9g11 and 3e2 (Complex)
- The fab of 9g11 (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of prefusion-stabilized RSV F (DS-Cav1 strain: A2) in complex with nAb 5B11
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8wz3
Q-score: 0.525
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus A2)
- 5b11 fab heavy chain (13 kDa, Protein from Mus musculus)
- 5b11 fab (Complex)
- Rsv a2 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus A2)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- Rsv fusion glycoprotein (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8wz5
Q-score: 0.418
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus B)
- Rsv b18537 pref in complex with humanized mab 5b11 (Complex)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- Rsv fusion glycoprotein (Complex from Human respiratory syncytial virus B)
- 5b11 fab heavy chain (12 kDa, Protein from Mus musculus)
- 5b11 fab (Complex from Mus musculus)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8wze
Q-score: 0.498
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv pre-fusion glycoprotein (Complex from Mus musculus)
- Rsv b18537 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus B)
- 5b11 fab (Complex)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- Rsv pre-fusion glycoprotein (29 kDa, Protein from Human respiratory syncytial virus B)
- 5b11 fab heavy chain (12 kDa, Protein from Mus musculus)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8wz4
Q-score: 0.488
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus A2)
- 5b11 fab heavy chain (13 kDa, Protein from Mus musculus)
- 5b11 fab (Complex)
- Rsv a2 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus A2)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- Rsv fusion glycoprotein (Complex from Mus musculus)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 7x35
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
Cryo-EM structure of EBV gHgL-gp42 in complex with mAbs 3E8 and 5E3 (localized refinement)
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 7yoy
Q-score: 0.464
Hong J, Zhong L, Liu L, Wu Q, Zhang W, Chen K, Wei D, Sun H, Zhou X, Zhang X, Kang YF, Huang Y, Chen J, Wang G, Zhou Y, Chen Y, Feng QS, Yu H, Li S, Zeng MS, Zeng YX, Xu M, Zheng Q, Chen Y, Zhang X, Xia N
Cell Rep Med (2023) 4 pp. 101296-101296 [ DOI: doi:10.1016/j.xcrm.2023.101296 Pubmed: 37992686 ]
- 3e8 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Gp42 (Complex from Human gammaherpesvirus 4)
- 5e3,3e8 (Complex from Oryctolagus cuniculus)
- 5e3 heavy chain (13 kDa, Protein from Oryctolagus cuniculus)
- Soluble gp42 (15 kDa, Protein from Human gammaherpesvirus 4)
- 3e8 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- 5e3 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Ebv ghgl-gp42 in complex with mabs 3e8 and 5e3 (Complex)
Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 10E4 (localized refinement)
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 7yp1
Q-score: 0.523
Hong J, Zhong L, Liu L, Wu Q, Zhang W, Chen K, Wei D, Sun H, Zhou X, Zhang X, Kang YF, Huang Y, Chen J, Wang G, Zhou Y, Chen Y, Feng QS, Yu H, Li S, Zeng MS, Zeng YX, Xu M, Zheng Q, Chen Y, Zhang X, Xia N
Cell Rep Med (2023) 4 pp. 101296-101296 [ DOI: doi:10.1016/j.xcrm.2023.101296 Pubmed: 37992686 ]
- Ebv gl (8 kDa, Protein from Human gammaherpesvirus 4)
- 10e4 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Ebv gh (22 kDa, Protein from Human gammaherpesvirus 4)
- Gh,gl (Complex from Human gammaherpesvirus 4)
- 10e4 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- 10e4 (Complex from Oryctolagus cuniculus)
- Ghgl-gp42 in complex with mab 10e4 (Complex)