CryoEM structure of isNS1 in complex with Fab56.2 and HDL
Chew BLA, Ngoh ANQ, Phoo WW, Chan KWK, Ser Z, Tulsian NK, Lim SS, Weng MJG, Watanabe S, Choy MM, Low J, Ooi EE, Ruedl C, Sobota RM, Vasudevan SG, Luo D
eLife (2024) 12 [ Pubmed: 38787378 DOI: doi:10.7554/eLife.90762 ]
- Monoclonal antibody fragment 56.2 (Complex from Mus musculus)
- Fab 56.2 heavy chain (Macromolecule from Mus musculus)
- Fab 56.2 light chain (Macromolecule from Mus musculus)
- Isns1ts (Complex from Dengue virus type 2)
- Core protein (Macromolecule from Dengue virus type 2)
- Ternary complex of fab56.2 with dengue virus nonstructural protein 1 and high density lipoprotein (Complex)
CryoEM structure of isNS1 in complex with Fab56.2
Chew BLA, Ngoh ANQ, Phoo WW, Chan KWK, Ser Z, Tulsian NK, Lim SS, Weng MJG, Watanabe S, Choy MM, Low J, Ooi EE, Ruedl C, Sobota RM, Vasudevan SG, Luo D
eLife (2024) 12 [ Pubmed: 38787378 DOI: doi:10.7554/eLife.90762 ]
- Fab56.2 heavy chain (Macromolecule from Mus musculus)
- Fab56.2 light chain (Macromolecule from Mus musculus)
- Fab56.2 (Complex from Mus musculus)
- Isns1ts (Complex from Dengue virus type 2)
- Ternary complex of fab56.2 with dengue virus nonstructural protein 1 and high density lipoprotein (Complex)
- Core protein (Macromolecule from dengue virus type 2)
Stalls V, Acharya P, Malewana D
To Be Published
- Dh1338 fab light chain (Macromolecule from Macaca mulatta)
- Spike glycoprotein hexapro (Macromolecule from Severe acute respiratory syndrome coronavirus 2)
- Dh1338 fab heavy chain (Macromolecule from Macaca mulatta)
- Ab026500 fab bound to sars-cov-2 hexapro spike trimer (556 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
To Be Published
- Vaccine elicited antibody dh1285 fab bound to ch505tfchim.6r.sosip.664.v4.1 trimer, 3-fab-bound configuration (353 kDa, Cellular component from Homo sapiens)
- Dh1285 fab light chain (Macromolecule from Macaca mulatta)
- Dh1285 fab heavy chain (Macromolecule from Macaca mulatta)
- Ch505tfchim.6r.sosip.664.v4.1 env trimer (Macromolecule from Human immunodeficiency virus 1)
To Be Published
- Dh1285 fab light chain (Macromolecule from Macaca mulatta)
- Dh1285 fab heavy chain (Macromolecule from Macaca mulatta)
- Ch505tfchim.6r.sosip.664.v4.1 env trimer (Macromolecule from Human immunodeficiency virus 1)
- Vaccine elicited antibody dh1285 fab bound to ch505tfchim.6r.sosip.664.v4.1. trimer, 2-fab-bound configuration (308 kDa, Cellular component from Homo sapiens)
SIVmac239.K180S SOSIP in complex with FZ019.2 Fab
Zhao F, Berndsen ZT, Pedreno-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, Coppola J, Weisgrau KL, Lifson JD, Nedellec R, Voigt TB, Laurino F, Louw J, Rosen BC, Ricciardi M, Crispin M, Desrosiers RC, Rakasz EG, Watkins DI, Andrabi R, Ward AB, Burton DR, Sok D
Nat Commun (2022) 13 pp. 5236-5236 [ DOI: doi:10.1038/s41467-022-32783-2 Pubmed: 36068229 ]
- Fz019.2 fab light chain (Macromolecule from Macaca mulatta)
- Fz019.2 fab heavy chain (Macromolecule from Macaca mulatta)
- Sivmac239.k180s sosip trimer in complex with 1 copy of fz019.2 fab (Complex from Simian immunodeficiency virus)
- Sivmac239.k180s sosip (Macromolecule from Simian immunodeficiency virus)
J08 fragment antigen binding in complex with Omicron SARS-CoV-2-6P S protein
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB
PNAS (2022) 119 pp. e2120976119-e2120976119 [ DOI: doi:10.1073/pnas.2120976119 Pubmed: 35549549 ]
- J08 fragment antigen binding in complex with omicron sars-cov-2-6p s protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- J08 fragment antigen binding light chain variable domain (Macromolecule from Homo sapiens)
- Omicron sars-cov-2-6p s protein (Macromolecule from Severe acute respiratory syndrome coronavirus 2)
- J08 fragment antigen binding heavy chain variable domain (Macromolecule from Homo sapiens)
Beta-44 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Liu C, Zhou D, Nutalai R, Duyvesteyn HME, Tuekprakhon A, Ginn HM, Dejnirattisai W, Supasa P, Mentzer AJ, Wang B, Case JB, Zhao Y, Skelly DT, Chen RE, Johnson SA, Ritter TG, Mason C, Malik T, Temperton N, Paterson NG, Williams MA, Hall DR, Clare DK, Howe A, Goulder PJR, Fry EE, Diamond MS, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR
Cell Host Microbe (2022) 30 pp. 53-68.e12 [ Pubmed: 34921776 DOI: doi:10.1016/j.chom.2021.11.013 ]
- Beta-44 fab in complex with sars-cov-2 beta-spike glycoprotein (475 kDa, Complex)
- Sars-cov-2 spike glycoprotein ectodomain, beta variant (Complex from Severe acute respiratory syndrome coronavirus 2)
- Beta-44 fab light chain (Macromolecule from Homo sapiens)
- Fab (Complex from Homo sapiens)
- Beta-44 fab heavy chain (Macromolecule from Homo sapiens)
- Sars-cov-2 spike glycoprotein ectodomain, beta variant (Macromolecule from Severe acute respiratory syndrome coronavirus 2)
CH505 SOSIP.664 trimer in complex with DH522.2 Fab
Williams WB, Zhang J, Jiang C, Nicely NI, Fera D, Luo K, Moody MA, Liao HX, Alam SM, Kepler TB, Ramesh A, Wiehe K, Holland JA, Bradley T, Vandergrift N, Saunders KO, Parks R, Foulger A, Xia SM, Bonsignori M, Montefiori DC, Louder M, Eaton A, Santra S, Scearce R, Sutherland L, Newman A, Bouton-Verville H, Bowman C, Bomze H, Gao F, Marshall DJ, Whitesides JF, Nie X, Kelsoe G, Reed SG, Fox CB, Clary K, Koutsoukos M, Franco D, Mascola JR, Harrison SC, Haynes BF, Verkoczy L
Nat Commun (2017) 8 pp. 1732-1732 [ DOI: doi:10.1038/s41467-017-01336-3 Pubmed: 29170366 ]
- Ch505 sosip.664 (Complex from Homo sapiens)
- Dh522.2 fab (Complex from Homo sapiens)
- Dh522.2 fab light chain (Macromolecule from Homo sapiens)
- Dh522.2 fab heavy chain (Macromolecule from Homo sapiens)
- Ch505 sosip.664 in complex with dh522.2 fab (Complex)
- Ch505 sosip.664 (Macromolecule from Human immunodeficiency virus 1)
92BR SOSIP.664 trimer in complex with DH270.1 Fab
Bonsignori M, Kreider EF, Fera D, Meyerhoff RR, Bradley T, Wiehe K, Alam SM, Aussedat B, Walkowicz WE, Hwang KK, Saunders KO, Zhang R, Gladden MA, Monroe A, Kumar A, Xia SM, Cooper M, Louder MK, McKee K, Bailer RT, Pier BW, Jette CA, Kelsoe G, Williams WB, Morris L, Kappes J, Wagh K, Kamanga G, Cohen MS, Hraber PT, Montefiori DC, Trama A, Liao HX, Kepler TB, Moody MA, Gao F, Danishefsky SJ, Mascola JR, Shaw GM, Hahn BH, Harrison SC, Korber BT, Haynes BF
Sci Transl Med (2017) 9 [ Pubmed: 28298420 DOI: doi:10.1126/scitranslmed.aai7514 ]