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sample_name:"Mediator of RNA polymerase II transcription subunit 17"
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Structure of human transcriptional Mediator complex

Release date: Oct. 9, 2024
Resolution: 8.2 Å
EM Method: Single-particle
Fitted PDBs: 8tqw
Q-score: 0.111

Chao TC, Chen SF, Kim HJ, Tang HC, Tseng HC, Xu A, Palao 3rd L, Khadka S, Li T, Huang MF, Lee DF, Murakami K, Boyer TG, Tsai KL

Mol Cell (2024) 84 pp. 3932-3949.e10 [ DOI: doi:10.1016/j.molcel.2024.09.001 Pubmed: 39321804 ]

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The IDRc bound human core Mediator complex

Release date: Oct. 9, 2024
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8trh
Q-score: 0.317

Chao TC, Chen SF, Kim HJ, Tang HC, Tseng HC, Xu A, Palao 3rd L, Khadka S, Li T, Huang MF, Lee DF, Murakami K, Boyer TG, Tsai KL

Mol Cell (2024) 84 pp. 3932-3949.e10 [ DOI: doi:10.1016/j.molcel.2024.09.001 Pubmed: 39321804 ]

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Atomic model of the mammalian mouse Mediator complex with CKM module

Release date: July 3, 2024
Resolution: 4.83 Å
EM Method: Single-particle
Fitted PDBs: 8t1l
Q-score: 0.247

Zhao H, Li J, Xiang Y, Malik S, Vartak SV, Veronezi GMB, Young N, Riney M, Kalchschmidt J, Conte A, Jung SK, Ramachandran S, Roeder RG, Shi Y, Casellas R, Asturias FJ

Mol Cell (2024) 84 pp. 2648-2664.e10 [ DOI: doi:10.1016/j.molcel.2024.06.006 Pubmed: 38955181 ]

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CryoEM structure of TR-TRAP

Release date: July 3, 2024
Resolution: 4.66 Å
EM Method: Single-particle
Fitted PDBs: 8t9d
Q-score: 0.215

Zhao H, Li J, Xiang Y, Malik S, Vartak SV, Veronezi GMB, Young N, Riney M, Kalchschmidt J, Conte A, Jung SK, Ramachandran S, Roeder RG, Shi Y, Casellas R, Asturias FJ

Mol Cell (2024) 84 pp. 2648-2664.e10 [ DOI: doi:10.1016/j.molcel.2024.06.006 Pubmed: 38955181 ]

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Atomic model of the mammalian Mediator complex with MED26 subunit

Release date: June 12, 2024
Resolution: 4.68 Å
EM Method: Single-particle
Fitted PDBs: 8t1i
Q-score: 0.238

Zhao H, Li J, Xiang Y, Malik S, Vartak SV, Veronezi GMB, Young N, Riney M, Kalchschmidt J, Conte A, Jung SK, Ramachandran S, Roeder RG, Shi Y, Casellas R, Asturias FJ

Mol Cell (2024) 84 pp. 2648-2664.e10 [ DOI: doi:10.1016/j.molcel.2024.06.006 Pubmed: 38955181 ]

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Yeast RNA polymerase II transcription pre-initiation complex with core Mediator

Release date: March 22, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8cen
Q-score: 0.269

Schilbach S, Wang H, Dienemann C, Cramer P

PNAS (2023) 120 pp. e2220542120-e2220542120 [ Pubmed: 37014863 DOI: doi:10.1073/pnas.2220542120 ]

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Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome

Release date: March 8, 2023
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8ceo
Q-score: 0.222

Schilbach S, Wang H, Dienemann C, Cramer P

PNAS (2023) 120 pp. e2220542120-e2220542120 [ Pubmed: 37014863 DOI: doi:10.1073/pnas.2220542120 ]

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Mediator-PIC Early (Composite Model)

Release date: March 1, 2023
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7uio
Q-score: 0.239

Gorbea Colon JJ, Palao 3rd L, Chen SF, Kim HJ, Snyder L, Chang YW, Tsai KL, Murakami K

Mol Cell (2023) 83 pp. 574- [ Pubmed: 36731470 DOI: doi:10.1016/j.molcel.2023.01.011 ]

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Core Mediator-PICearly (Copy A)

Release date: Feb. 15, 2023
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7ui9
Q-score: 0.294

Gorbea Colon JJ, Palao 3rd L, Chen SF, Kim HJ, Snyder L, Chang YW, Tsai KL, Murakami K

Mol Cell (2023) 83 pp. 574- [ Pubmed: 36731470 DOI: doi:10.1016/j.molcel.2023.01.011 ]

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Mediator-PIC Early (Core B)

Release date: Feb. 15, 2023
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 7uif
Q-score: 0.127

Gorbea Colon JJ, Palao 3rd L, Chen SF, Kim HJ, Snyder L, Chang YW, Tsai KL, Murakami K

Mol Cell (2023) 83 pp. 574- [ Pubmed: 36731470 DOI: doi:10.1016/j.molcel.2023.01.011 ]

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