Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7zm8
Q-score: 0.604
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Mitochondrial nadh:ubiquinone oxidoreductase in ddm (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Structure of mammalian respiratory Complex I, class1
Resolution: 4.27 Å
EM Method: Single-particle
Fitted PDBs: 5ldw
Q-score: 0.33
Zhu J, Vinothkumar KR, Hirst J
Nature (2016) 536 pp. 354-358 [ Pubmed: 27509854 DOI: doi:10.1038/nature19095 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, ndufa13,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, ndufa13,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, ndufa13,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, ndufa13 (14 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (49 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, ndufs6,nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial,nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (8 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3, ndufa3 (7 kDa, Protein from Bos taurus)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7, ndufa7 (7 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (26 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, ndufs4 (9 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6, ndufb6 (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, ndufv3 (2 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, ndufb8 (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Bos taurus)
- Bovine respiratory complex i (1 MDa, Complex from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4, ndufb4,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4, ndufb4,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (13 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial,nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (71 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2, ndufc2,nadh dehydrogenase [ubiquinone] 1 subunit c2,nadh dehydrogenase [ubiquinone] 1 subunit c2, ndufc2,nadh dehydrogenase [ubiquinone] 1 subunit c2,nadh dehydrogenase [ubiquinone] 1 subunit c2, ndufc2,nadh dehydrogenase [ubiquinone] 1 subunit c2,nadh dehydrogenase [ubiquinone] 1 subunit c2, ndufc2 (11 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (48 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (20 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, ndufa10,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, ndufa10,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (34 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, ndufb5 (12 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, ndufb10,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, ndufb10,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, ndufb10,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, ndufb10 (16 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, ndufa9 (25 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (14 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8,nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, ndufa8 (18 kDa, Protein from Bos taurus)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9,nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9, ndufb9 (19 kDa, Protein from Bos taurus)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Bos taurus)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, ndufb2 (4 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Bos taurus)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3, ndufb3 (6 kDa, Protein from Bos taurus)