Structural complex of neuropeptide Y receptor 2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8k6n
Q-score: 0.379
Shen S, Deng Y, Shen C, Chen H, Cheng L, Wu C, Zhao C, Yang Z, Hou H, Wang K, Shao Z, Deng C, Ye F, Yan W
MedComm (2020) (2024) 5 pp. e565-e565 [ DOI: doi:10.1002/mco2.565 Pubmed: 38882210 ]
- Scfv16 (28 kDa, Protein from Mus musculus)
- Structural complex of neuropeptide y receptor 1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-2 (40 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 2 (38 kDa, Protein from Homo sapiens)
- C-flanking peptide of npy (4 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Structural complex of neuropeptide Y receptor 1
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8k6o
Q-score: 0.34
Shen S, Deng Y, Shen C, Chen H, Cheng L, Wu C, Zhao C, Yang Z, Hou H, Wang K, Shao Z, Deng C, Ye F, Yan W
MedComm (2020) (2024) 5 pp. e565-e565 [ DOI: doi:10.1002/mco2.565 Pubmed: 38882210 ]
- Scfv16 (28 kDa, Protein from Mus musculus)
- Structural complex of neuropeptide y receptor 1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-2 (40 kDa, Protein from Homo sapiens)
- C-flanking peptide of npy (4 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 7yoo
Q-score: 0.531
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ Pubmed: 36525977 DOI: doi:10.1016/j.str.2022.11.010 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Scfv16 (Complex)
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Npy (Complex)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein (Complex from Mus musculus)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Consensus map)
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ Pubmed: 36525977 DOI: doi:10.1016/j.str.2022.11.010 ]
- Npy (Complex)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein (Complex from Mus musculus)
- Scfv16 (Complex)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Focused map on NPY-Y2R)
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ Pubmed: 36525977 DOI: doi:10.1016/j.str.2022.11.010 ]
- Npy (Complex)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein (Complex from Mus musculus)
- Scfv16 (Complex)
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ Pubmed: 36525977 DOI: doi:10.1016/j.str.2022.11.010 ]
- Npy (Complex)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein (Complex from Mus musculus)
- Scfv16 (Complex)
Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7x9a
Q-score: 0.411
Tang T, Tan Q, Han S, Diemar A, Lobner K, Wang H, Schuss C, Behr V, Morl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, Kaiser A, Beck-Sickinger AG, Zhao Q, Wu B
Sci Adv (2022) 8 pp. eabm1232-eabm1232 [ DOI: doi:10.1126/sciadv.abm1232 Pubmed: 35507650 ]
- Neuropeptide y receptor type 1 (43 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y y1 receptor in complex with npy and gi (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Neuropeptide y y1 receptor and gi (Complex)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Neuropeptide y (Complex)
Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7x9b
Q-score: 0.394
Tang T, Tan Q, Han S, Diemar A, Lobner K, Wang H, Schuss C, Behr V, Morl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, Kaiser A, Beck-Sickinger AG, Zhao Q, Wu B
Sci Adv (2022) 8 pp. eabm1232-eabm1232 [ DOI: doi:10.1126/sciadv.abm1232 Pubmed: 35507650 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Neuropeptide y y2 receptor and gi (Complex)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Neuropeptide y (Complex)
- Neuropeptide y y2 receptor in complex with npy and gi (Complex from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7vgx
Q-score: 0.501
Park C, Kim J, Ko SB, Choi YK, Jeong H, Woo H, Kang H, Bang I, Kim SA, Yoon TY, Seok C, Im W, Choi HJ
Nat Commun (2022) 13 pp. 853- [ DOI: doi:10.1038/s41467-022-28510-6 ]
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
- Single-chain antibody fv fragment (scfv16) (Complex from Mus musculus)
- Complex of neuropeptide y y1 receptor (npy1r) with its endogeneous peptide-agonist neuropeptide y (npy), g protein and g-protein stabilizing antibody fragement (scfv16) (160 kDa, Complex)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 1 (46 kDa, Protein from Homo sapiens)
- Nucleotide-free g-protein heterotrimer (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Neuropeptide y y1 receptor (npy1r) (Complex from Homo sapiens)
- Neuropeptide y (Complex)