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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"Nucleoporin NUP53"

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EMDB [4]

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EMD-41300

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Inner spoke ring of the yeast NPC

Release date: Oct. 11, 2023
Resolution: 6.6 Å
EM Method: Single-particle
Fitted PDBs: 8tj5
Q-score: 0.113

Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP

Mol Cell (2023) 83 pp. 3283-3302.e5 [ DOI: doi:10.1016/j.molcel.2023.08.025 Pubmed: 37738963 ]

Sample:

Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
Spoke connector (3 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin 59 (58 kDa, Protein from Saccharomyces cerevisiae)
Nuclear pore complex (18 MDa, Complex from Saccharomyces cerevisiae)

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EMD-24057

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Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96-Nup53-Nup145N complex (Nup192 residues 1-1756; Nic96 residues 240-301; Nup53 31-67; Nup145N 616-683)

Release date: June 15, 2022
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 7mvv
Q-score: 0.324

Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A

Science (2022) 376 pp. eabm9798-eabm9798 [ Pubmed: 35679425 DOI: doi:10.1126/science.abm9798 ]

Sample:

Nucleoporin nup192 (200 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
Nucleoporin nup53 (4 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
Nup192-nic96-nup53-nup145n heterotetramer (215 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
Nucleoporin nic96 (7 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
Nucleoporin nup145n (7 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))

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EMD-24232

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Inner ring spoke from the isolated yeast NPC

Release date: Jan. 26, 2022
Resolution: 7.6 Å
EM Method: Single-particle
Fitted PDBs: 7n85
Q-score: 0.113

Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP

Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]

Sample:

Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin asm4 (58 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
Unknown connectors (3 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
Spoke from yeast inner ring (16 MDa, Complex from Saccharomyces cerevisiae)

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EMD-24258

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Structure of the in situ yeast NPC

Release date: Jan. 26, 2022
Resolution: 37.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7n9f
Q-score: 0.043

Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP

Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]

Sample:

Nucleoporin asm4 (58 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin seh1 (39 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
Orphans bound to nup192 ntd (3 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup133 (133 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
Dynein light chain 1, cytoplasmic (10 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup82 (82 kDa, Protein from Saccharomyces cerevisiae)
Yeast npc (52 MDa, Cellular component from Saccharomyces cerevisiae)
Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin nup159 (159 kDa, Protein from Saccharomyces cerevisiae)
Nucleoporin 145c (81 kDa, Protein from Saccharomyces cerevisiae)

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Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

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Select database:

EMDB [4]

Format:

Select the script type:

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