Human nuclear pore complex (dilated)
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Nuclear pore complex protein nup96 (106 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup98 (91 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup85 (75 kDa, Protein from Homo sapiens)
- Nucleoporin seh1 (39 kDa, Protein from Homo sapiens)
- Nucleoporin nup35 (34 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup160 (162 kDa, Protein from Homo sapiens)
- Protein elys (252 kDa, Protein from Homo sapiens)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from Homo sapiens)
- Nucleoporin nup188 homolog (196 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup107 (106 kDa, Protein from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup155 (155 kDa, Protein from Homo sapiens)
- Nucleoporin ndc1 (76 kDa, Protein from Homo sapiens)
- Nucleoporin p54 (55 kDa, Protein from Homo sapiens)
- Protein sec13 homolog (35 kDa, Protein from Homo sapiens)
- Human nuclear pore complex from hek cells (Cellular component from Homo sapiens)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from Homo sapiens)
- Nucleoporin nup43 (42 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup88 (83 kDa, Protein from Homo sapiens)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup133 (129 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup205 (228 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Homo sapiens)
- Aladin (59 kDa, Protein from Homo sapiens)
- Nucleoporin p58/p45 (60 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup214 (213 kDa, Protein from Homo sapiens)
Human nuclear pore complex (constricted)
Resolution: 12.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7r5k
Q-score: 0.034
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Nuclear pore complex protein nup96 (106 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup98 (91 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup85 (75 kDa, Protein from Homo sapiens)
- Nucleoporin seh1 (39 kDa, Protein from Homo sapiens)
- Nucleoporin nup35 (34 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup160 (162 kDa, Protein from Homo sapiens)
- Protein elys (252 kDa, Protein from Homo sapiens)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from Homo sapiens)
- Nucleoporin nup188 homolog (196 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup107 (106 kDa, Protein from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup155 (155 kDa, Protein from Homo sapiens)
- Nucleoporin ndc1 (76 kDa, Protein from Homo sapiens)
- Nucleoporin p54 (55 kDa, Protein from Homo sapiens)
- Protein sec13 homolog (35 kDa, Protein from Homo sapiens)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from Homo sapiens)
- Nucleoporin nup43 (42 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup88 (83 kDa, Protein from Homo sapiens)
- Nuclear pore complex (120 MDa, Cellular component from Homo sapiens)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup133 (129 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup205 (228 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Homo sapiens)
- Aladin (59 kDa, Protein from Homo sapiens)
- Nucleoporin p58/p45 (60 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup214 (213 kDa, Protein from Homo sapiens)
Double nuclear outer ring from the isolated yeast NPC
Resolution: 11.6 Å
EM Method: Single-particle
Fitted PDBs: 7n84
Q-score: 0.063
Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP
Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]
- Nucleoporin seh1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin 145c (81 kDa, Protein from Saccharomyces cerevisiae)
- Yeast double outer ring (10 MDa, Complex from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup133 (133 kDa, Protein from Saccharomyces cerevisiae)
- Unknown (5 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
Structure of the in situ yeast NPC
Resolution: 37.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7n9f
Q-score: 0.043
Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP
Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]
- Nucleoporin asm4 (58 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin seh1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
- Orphans bound to nup192 ntd (3 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup133 (133 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
- Dynein light chain 1, cytoplasmic (10 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup82 (82 kDa, Protein from Saccharomyces cerevisiae)
- Yeast npc (52 MDa, Cellular component from Saccharomyces cerevisiae)
- Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup159 (159 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin 145c (81 kDa, Protein from Saccharomyces cerevisiae)