Double nuclear outer ring of Nup84-complexes from the yeast NPC
Resolution: 8.1 Å
EM Method: Single-particle
Fitted PDBs: 8tie
Q-score: 0.08
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP
Mol Cell (2023) 83 pp. 3283-3302.e5 [ DOI: doi:10.1016/j.molcel.2023.08.025 Pubmed: 37738963 ]
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
- Nuclear pore complex (Complex from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Double nup84 y-complex (Complex from Saccharomyces cerevisiae)
- Nup133 isoform 1 (133 kDa, Protein from Saccharomyces cerevisiae)
- Nup145 isoform 1 (145 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin seh1 (34 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
The cryo-EM map of the core region from the X. laevis NPC CR subunit
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7fik
Q-score: 0.346
Zhu X, Huang G, Zeng C, Zhan X, Liang K, Xu Q, Zhao Y, Wang P, Wang Q, Zhou Q, Tao Q, Liu M, Lei J, Yan C, Shi Y
Science (2022) 376 pp. eabl8280-eabl8280 [ Pubmed: 35679404 DOI: doi:10.1126/science.abl8280 ]
- Nuclear pore complex protein (105 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup85 (75 kDa, Protein from Xenopus laevis)
- Nup155-prov protein (154 kDa, Protein from Xenopus laevis)
- Outer nup160 (162 kDa, Protein from Xenopus laevis)
- Nucleoporin nup88a (82 kDa, Protein from Xenopus laevis)
- Mgc83295 protein (227 kDa, Protein from Xenopus laevis)
- Nucleoporin seh1-b (39 kDa, Protein from Xenopus laevis)
- Nup98 (13 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup133 (111 kDa, Protein from Xenopus laevis)
- Mgc154553 protein (41 kDa, Protein from Xenopus laevis)
- Outer nup133 (127 kDa, Protein from Xenopus laevis)
- Xenopus laevis nuclear pore complex (npc) (Complex from Xenopus laevis)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup98-nup96 (191 kDa, Protein from Xenopus laevis)
- Mgc83926 protein (36 kDa, Protein from Xenopus laevis)
- Protein sec13 homolog (35 kDa, Protein from Xenopus laevis)
- Nup358 complex, clamps (322 kDa, Protein from Xenopus laevis)
Human nuclear pore complex (dilated)
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
- Nuclear pore complex protein nup85 (75 kDa, Protein from Homo sapiens)
- Nucleoporin p58/p45 (60 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup160 (162 kDa, Protein from Homo sapiens)
- Nucleoporin seh1 (39 kDa, Protein from Homo sapiens)
- Nucleoporin nup43 (42 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup98 (91 kDa, Protein from Homo sapiens)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from Homo sapiens)
- Nucleoporin p54 (55 kDa, Protein from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from Homo sapiens)
- Human nuclear pore complex from hek cells (Cellular component from Homo sapiens)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from Homo sapiens)
- Nucleoporin ndc1 (76 kDa, Protein from Homo sapiens)
- Nucleoporin nup35 (34 kDa, Protein from Homo sapiens)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup96 (106 kDa, Protein from Homo sapiens)
- Protein sec13 homolog (35 kDa, Protein from Homo sapiens)
- Nucleoporin nup188 homolog (196 kDa, Protein from Homo sapiens)
- Aladin (59 kDa, Protein from Homo sapiens)
- Protein elys (252 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup214 (213 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup205 (228 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup133 (129 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup107 (106 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup88 (83 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup155 (155 kDa, Protein from Homo sapiens)
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 7uhy
Q-score: 0.415
Valenstein ML, Rogala KB, Lalgudi PV, Brignole EJ, Gu X, Saxton RA, Chantranupong L, Kolibius J, Quast JP, Sabatini DM
Nature (2022) 607 pp. 610-616 [ DOI: doi:10.1038/s41586-022-04939-z Pubmed: 35831510 ]
- Gator complex protein wdr59 (109 kDa, Protein from Homo sapiens)
- Protein sec13 homolog (35 kDa, Protein from Homo sapiens)
- Gator complex protein wdr24 (88 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Unknown (1 kDa, Protein from Homo sapiens)
- Gator complex protein mios (100 kDa, Protein from Homo sapiens)
- Human gator2 (1 MDa, Complex from Homo sapiens)
- Isoform b of nucleoporin seh1 (46 kDa, Protein from Homo sapiens)
- Unknown (698 Da, Protein from Homo sapiens)
Human nuclear pore complex (constricted)
Resolution: 12.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7r5k
Q-score: 0.034
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
- Nuclear pore complex protein nup85 (75 kDa, Protein from Homo sapiens)
- Nucleoporin p58/p45 (60 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup160 (162 kDa, Protein from Homo sapiens)
- Nucleoporin seh1 (39 kDa, Protein from Homo sapiens)
- Nucleoporin nup43 (42 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup98 (91 kDa, Protein from Homo sapiens)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from Homo sapiens)
- Nucleoporin p54 (55 kDa, Protein from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from Homo sapiens)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from Homo sapiens)
- Nuclear pore complex (120 MDa, Cellular component from Homo sapiens)
- Nucleoporin ndc1 (76 kDa, Protein from Homo sapiens)
- Nucleoporin nup35 (34 kDa, Protein from Homo sapiens)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup96 (106 kDa, Protein from Homo sapiens)
- Protein sec13 homolog (35 kDa, Protein from Homo sapiens)
- Nucleoporin nup188 homolog (196 kDa, Protein from Homo sapiens)
- Aladin (59 kDa, Protein from Homo sapiens)
- Protein elys (252 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup214 (213 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup205 (228 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup133 (129 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup107 (106 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup88 (83 kDa, Protein from Homo sapiens)
- Nuclear pore complex protein nup155 (155 kDa, Protein from Homo sapiens)
Cryo-EM structure of the NR subunit from X. laevis NPC
Resolution: 5.6 Å
EM Method: Single-particle
Fitted PDBs: 7wb4
Q-score: 0.214
Huang G, Zhan X, Zeng C, Zhu X, Liang K, Zhao Y, Wang P, Wang Q, Zhou Q, Tao Q, Liu M, Lei J, Yan C, Shi Y
Cell Res (2022) 32 pp. 349-358 [ DOI: doi:10.1038/s41422-021-00610-w Pubmed: 35177819 ]
- Nuclear pore complex protein (105 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup96 (105 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup85 (75 kDa, Protein from Xenopus laevis)
- Nup155-prov protein (154 kDa, Protein from Xenopus laevis)
- Outer nup160 (162 kDa, Protein from Xenopus laevis)
- Protein elys (268 kDa, Protein from Xenopus laevis)
- The nr subunit (Complex from Xenopus laevis)
- Nucleoporin seh1-b (39 kDa, Protein from Xenopus laevis)
- Gator complex protein sec13 (35 kDa, Protein from Xenopus laevis)
- Mgc83295 protein (227 kDa, Protein from Xenopus laevis)
- Mgc154553 protein (41 kDa, Protein from Xenopus laevis)
- Outer nup133 (127 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Xenopus laevis)
- Mgc83926 protein (36 kDa, Protein from Xenopus laevis)
Double nuclear outer ring from the isolated yeast NPC
Resolution: 11.6 Å
EM Method: Single-particle
Fitted PDBs: 7n84
Q-score: 0.063
Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP
Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]
- Unknown (5 kDa, Protein from Saccharomyces cerevisiae)
- Yeast double outer ring (10 MDa, Complex from Saccharomyces cerevisiae)
- Nucleoporin nup133 (133 kDa, Protein from Saccharomyces cerevisiae)
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin 145c (81 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin seh1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
Structure of the in situ yeast NPC
Resolution: 37.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7n9f
Q-score: 0.043
Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP
Cell (2022) 185 pp. 361-378.e25 [ Pubmed: 34982960 DOI: doi:10.1016/j.cell.2021.12.015 ]
- Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup82 (82 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup159 (159 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin seh1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
- Dynein light chain 1, cytoplasmic (10 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup133 (133 kDa, Protein from Saccharomyces cerevisiae)
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin 145c (81 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
- Yeast npc (52 MDa, Cellular component from Saccharomyces cerevisiae)
- Nucleoporin asm4 (58 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
- Orphans bound to nup192 ntd (3 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 5.5 Å
EM Method: Single-particle
Fitted PDBs: 6lk8
Q-score: 0.089
Huang G, Zhang Y, Zhu X, Zeng C, Wang Q, Zhou Q, Tao Q, Liu M, Lei J, Yan C, Shi Y
Cell Res (2020) 30 pp. 520-531 [ Pubmed: 32376910 DOI: doi:10.1038/s41422-020-0319-4 ]
- Nup214 complex coiled coil region 2, helix 1 (2 kDa, Protein from Xenopus laevis)
- Bridge domain (33 kDa, Protein from Xenopus laevis)
- Nup214 complex coiled coil region 2, helix 2 (2 kDa, Protein from Xenopus laevis)
- Cytoplasmic ring subunit of xenopus laevis npc (Complex from Xenopus laevis)
- Nup214 complex coiled coil region 1, helix 3 (6 kDa, Protein from Xenopus laevis)
- Nup214 complex coiled coil region 1, helix 2 (6 kDa, Protein from Xenopus laevis)
- Outer nup133 (127 kDa, Protein from Xenopus laevis)
- Nup358 complex, clamps (322 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup85 (75 kDa, Protein from Xenopus laevis)
- Gator complex protein sec13 (35 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein (105 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup96 (105 kDa, Protein from Xenopus laevis)
- Mgc83295 protein (227 kDa, Protein from Xenopus laevis)
- Nucleoporin seh1-a (36 kDa, Protein from Xenopus laevis)
- Nup214 complex coiled coil region 2, helix 3 (2 kDa, Protein from Xenopus laevis)
- Outer nup160 (162 kDa, Protein from Xenopus laevis)
- Mgc154553 protein (41 kDa, Protein from Xenopus laevis)
- Mgc83926 protein (36 kDa, Protein from Xenopus laevis)
- Nup214 complex coiled-coil region 1, helix 1 (5 kDa, Protein from Xenopus laevis)