Cryo-EM structure of OSCA1.2-liposome-inside-in open state
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8xaj
Q-score: 0.42
Cryo-EM structure of OSCA1.2-liposome-inside-out closed state
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8xng
Q-score: 0.398
Cryo-EM structure of OSCA1.2-DOPC-1:20-contracted1 state
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 8xs4
Q-score: 0.48
Cryo-EM structure of OSCA1.2-DOPC-1:20-contracted2 state
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8xs5
Q-score: 0.456
Cryo-EM structure of OSCA1.2-DOPC-1:20-expanded state
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8xvx
Q-score: 0.473
Cryo-EM structure of OSCA1.2-DOPC-1:50-contracted state
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8xw2
Q-score: 0.433
Cryo-EM structure of OSCA1.2-DOPC-1:50-expanded state
Resolution: 3.63 Å
EM Method: Single-particle
Fitted PDBs: 8xw3
Q-score: 0.44
Structure of mechanically activated ion channel OSCA1.2 in peptidiscs
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8t56
Q-score: 0.584
Jojoa-Cruz S, Burendei B, Lee WH, Ward AB
Structure (2024) 32 pp. 157- [ Pubmed: 38103547 DOI: doi:10.1016/j.str.2023.11.009 ]
- Nspr peptide (4 kDa, Protein from synthetic construct)
- Palmitic acid (256 Da, Ligand)
- Calcium permeable stress-gated cation channel 1 (89 kDa, Protein from Arabidopsis thaliana)
- Cholesterol hemisuccinate (486 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Peptidisc peptide (Complex from synthetic construct)
- Osca1.2 (Complex from Arabidopsis thaliana)
- Osca1.2 in peptidisc (176 kDa, Complex)
- Cholesterol (386 Da, Ligand)
Structure of the rice hyperosmolality-gated ion channel OSCA1.2
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6oce
Q-score: 0.24
Maity K, Heumann JM, McGrath AP, Kopcho NJ, Hsu PK, Lee CW, Mapes JH, Garza D, Krishnan S, Morgan GP, Hendargo KJ, Klose T, Rees SD, Medrano-Soto A, Saier Jr MH, Pineros M, Komives EA, Schroeder JI, Chang G, Stowell MHB
PNAS (2019) 116 pp. 14309-14318 [ Pubmed: 31227607 DOI: doi:10.1073/pnas.1900774116 ]
- Stress-gated cation channel 1.2 (88 kDa, Protein from Oryza sativa subsp. japonica)
- Osca1.2 dimer (180 kDa, Complex from Oryza sativa subsp. japonica)
Cryo-EM map of mechanically activated ion channel OSCA1.2 in nanodisc
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6mgv
Q-score: 0.502
Jojoa Cruz S, Saotome K, Murthy SE, Tsui CCA, Sansom MS, Patapoutian A, Ward AB
eLife (2018) 7 [ Pubmed: 30382939 DOI: doi:10.7554/eLife.41845 ]
- Calcium permeable stress-gated cation channel 1 (89 kDa, Protein from Arabidopsis thaliana)
- Osca1.2 (88 kDa, Cellular component from Arabidopsis thaliana)