Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 8yni
Q-score: 0.403
Yang CY, Tseng YC, Tu YF, Kuo BJ, Hsu LC, Lien CI, Lin YS, Wang YT, Lu YC, Su TW, Lo YC, Lin SC
Nat Commun (2024) 15 pp. 8974-8974 [ Pubmed: 39419969 DOI: doi:10.1038/s41467-024-53306-1 ]
- Fas-associated death domain protein (24 kDa, Protein from Homo sapiens)
- Casp8 and fadd-like apoptosis regulator subunit p43 (20 kDa, Protein from Homo sapiens)
- Caspase-8 subunit p10 (55 kDa, Protein from Homo sapiens)
- Fadd/caspase-8/cflip death effector domain assembly (Complex from Homo sapiens)
Structure of the Caspase-8/cFLIP death effector domain assembly
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8ynk
Q-score: 0.404
Yang CY, Tseng YC, Tu YF, Kuo BJ, Hsu LC, Lien CI, Lin YS, Wang YT, Lu YC, Su TW, Lo YC, Lin SC
Nat Commun (2024) 15 pp. 8974-8974 [ Pubmed: 39419969 DOI: doi:10.1038/s41467-024-53306-1 ]
- Casp8 and fadd-like apoptosis regulator subunit p43 (20 kDa, Protein from Homo sapiens)
- Caspase-8 subunit p10 (55 kDa, Protein from Homo sapiens)
- Fadd/caspase-8/cflip death effector domain assembly (Complex from Homo sapiens)
Structure of the Caspase-8/cFLIP death effector domain assembly
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8ynl
Q-score: 0.427
Yang CY, Tseng YC, Tu YF, Kuo BJ, Hsu LC, Lien CI, Lin YS, Wang YT, Lu YC, Su TW, Lo YC, Lin SC
Nat Commun (2024) 15 pp. 8974-8974 [ Pubmed: 39419969 DOI: doi:10.1038/s41467-024-53306-1 ]
- Casp8 and fadd-like apoptosis regulator subunit p43 (20 kDa, Protein from Homo sapiens)
- Caspase-8/cflip death effector domain assembly (Complex from Homo sapiens)
- Caspase-8 subunit p10 (55 kDa, Protein from Homo sapiens)
Structure of the Caspase-8/cFLIP death effector domain assembly
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 8ynm
Q-score: 0.439
Yang CY, Tseng YC, Tu YF, Kuo BJ, Hsu LC, Lien CI, Lin YS, Wang YT, Lu YC, Su TW, Lo YC, Lin SC
Nat Commun (2024) 15 pp. 8974-8974 [ DOI: doi:10.1038/s41467-024-53306-1 Pubmed: 39419969 ]
- Caspase-8 subunit p10 (55 kDa, Protein from Homo sapiens)
- Casp8 and fadd-like apoptosis regulator subunit p43 (20 kDa, Protein from Homo sapiens)
- Caspase-8/cflip death effector domain assembly (Complex from Homo sapiens)
Structure of the Caspase-8/cFLIP death effector domain assembly
Resolution: 3.97 Å
EM Method: Single-particle
Fitted PDBs: 8ynn
Q-score: 0.321
Yang CY, Tseng YC, Tu YF, Kuo BJ, Hsu LC, Lien CI, Lin YS, Wang YT, Lu YC, Su TW, Lo YC, Lin SC
Nat Commun (2024) 15 pp. 8974-8974 [ Pubmed: 39419969 DOI: doi:10.1038/s41467-024-53306-1 ]
- Casp8 and fadd-like apoptosis regulator subunit p43 (20 kDa, Protein from Homo sapiens)
- Caspase-8/cflip death effector domain assembly (Complex from Homo sapiens)
- Caspase-8 subunit p10 (55 kDa, Protein from Homo sapiens)
Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 8ybx
Q-score: 0.419
Yang CY, Lien CI, Tseng YC, Tu YF, Kulczyk AW, Lu YC, Wang YT, Su TW, Hsu LC, Lo YC, Lin SC
Nat Commun (2024) 15 pp. 3791-3791 [ Pubmed: 38710704 DOI: doi:10.1038/s41467-024-47990-2 ]
- Casp8 and fadd-like apoptosis regulator subunit p43 (20 kDa, Protein from Homo sapiens)
- Fas-associated death domain protein (24 kDa, Protein from Homo sapiens)
- Caspase-8 subunit p10 (55 kDa, Protein from Homo sapiens)
- Fadd/caspase-8/cflip death effector domain assembly (Complex from Homo sapiens)
Acinetobacter baylyi LptB2FG bound to lipopolysaccharide and a macrocyclic peptide
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8frl
Q-score: 0.546
Pahil KS, Gilman MSA, Baidin V, Clairfeuille T, Mattei P, Bieniossek C, Dey F, Muri D, Baettig R, Lobritz M, Bradley K, Kruse AC, Kahne D
Nature (2024) 625 pp. 572-577 [ DOI: doi:10.1038/s41586-023-06799-7 Pubmed: 38172635 ]
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Lipopolysaccharide export system atp-binding protein lptb (29 kDa, Protein from Acinetobacter baylyi ADP1)
- Lipopolysaccharide export system permease protein lptf (41 kDa, Protein from Acinetobacter baylyi ADP1)
- Inner membrane lipopolysaccharide transporter composed of lptf, lptg and two molecules of lptb in complex with lipopolysaccharide and a macrocyclic peptide. (139 kDa, Complex from Acinetobacter baylyi ADP1)
- (2~{r},4~{r},5~{r},6~{r})-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-[(2~{r},4~{r},5~{r},6~{r})-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-5-[(2~{s},3~{s},4~{r},5~{r},6~{r})-6-[(1~{s})-1,2-bis(oxidanyl)ethyl]-4-[(2~{r},3~{s},4~{r},5~{s},6~{r})-6-[(1~{s})-2-[(2~{s},3~{s},4~{s},5~{s},6~{r})-6-[(1~{s})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-5-[[(3~{r})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-3-oxidanyl-5-[[(3~{r})-3-oxidanyltetradecanoyl]amino]-4-[(3~{r})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{r})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid (2 kDa, Ligand)
- Lps export abc transporter permease lptg (40 kDa, Protein from Acinetobacter baylyi ADP1)
- (7s,10s,13s,17p)-10-(4-aminobutyl)-7-(3-aminopropyl)-17-(6-aminopyridin-3-yl)-20-chloro-13-[(1h-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5h)-trione (797 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ufh
Q-score: 0.519
Pahil KS, Gilman MSA, Baidin V, Clairfeuille T, Mattei P, Bieniossek C, Dey F, Muri D, Baettig R, Lobritz M, Bradley K, Kruse AC, Kahne D
Nature (2024) 625 pp. 572-577 [ DOI: doi:10.1038/s41586-023-06799-7 Pubmed: 38172635 ]
- Lipopolysaccharide export system atp-binding protein lptb (29 kDa, Protein from Acinetobacter baylyi ADP1)
- (2~{r},4~{r},5~{r},6~{r})-2-[(2~{r},4~{r},5~{r},6~{r})-5-[(2~{s},4~{r},5~{r},6~{r})-4-[(2~{r},3~{r},4~{r},5~{s},6~{s})-3-acetamido-6-carboxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-carboxy-5-oxidanyl-oxan-2-yl]oxy-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-4-[(3~{s})-3-dodecanoyloxydodecanoyl]oxy-6-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-5-[[(3~{r})-3-heptanoyloxynonanoyl]amino]-3-oxidanyl-4-[(3~{r})-3-oxidanyloctanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-5-[[(3~{s})-3-[(3~{r})-3-oxidanyldodecanoyl]oxydecanoyl]amino]-3-phosphonooxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-4,5-bis(oxidanyl)oxane-2-carboxylic acid (2 kDa, Ligand)
- Lipopolysaccharide export system permease protein lptf (41 kDa, Protein from Acinetobacter baylyi ADP1)
- Lps export abc transporter permease lptg (40 kDa, Protein from Acinetobacter baylyi ADP1)
- (7s,10s,13s,17p)-10-(4-aminobutyl)-7-(3-aminopropyl)-17-(6-aminopyridin-3-yl)-20-chloro-13-[(1h-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5h)-trione (797 Da, Ligand)
- Inner membrane lipopolysaccharide transporter composed of lptf, lptg, and two molecules of lptb in complex with lipopolysaccharide and a macrocyclic peptide (139 kDa, Complex from Acinetobacter baylyi ADP1)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8spb
Q-score: 0.415
Devant P, Dong Y, Mintseris J, Ma W, Gygi SP, Wu H, Kagan JC
Nature (2023) 624 pp. 451-459 [ Pubmed: 37993712 DOI: doi:10.1038/s41586-023-06751-9 ]
- Interleukin-18 (21 kDa, Protein from Homo sapiens)
- Caspase-4 subunit p10 (10 kDa, Protein from Homo sapiens)
- Caspase-4 subunit p20 (23 kDa, Protein from Homo sapiens)
- Caspase-4 in complex with pro-il-18 (144 kDa, Complex from Homo sapiens)
Cryo-electron tomography of P10BP10 synthetic collagen fibers