Resolution: 4.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nb8
Q-score: 0.268
Cook AD, Roberts AJ, Atherton J, Tewari R, Topf M, Moores CA
J Biol Chem (2021) 297 pp. 101063-101063 [ DOI: doi:10.1016/j.jbc.2021.101063 Pubmed: 34375637 ]
- Kinesin-5 (Complex from Plasmodium falciparum (isolate 3D7))
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 14 protofilament microtubule of alpha/beta-tubulin dimers, with kinesin-5 motor domain bound 1:1 to tubulin dimers. (Complex)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Kinesin-5 (46 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Magnesium ion (24 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Alpha/beta-tubulin (Complex from Sus scrofa)
Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nba
Q-score: 0.268
Cook AD, Roberts AJ, Atherton J, Tewari R, Topf M, Moores CA
J Biol Chem (2021) 297 pp. 101063-101063 [ DOI: doi:10.1016/j.jbc.2021.101063 Pubmed: 34375637 ]
- 14 protofilament microtubule complexed with plasmodium falciparum kinesin-5 motor domain bound to amppnp. asymmetric unit. (Complex from Plasmodium falciparum (isolate NF54))
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Kinesin motor domain-containing protein,kinesin motor domain-containing protein (46 kDa, Protein from Plasmodium falciparum (isolate NF54))
Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6i2i
Q-score: 0.422
Adib R, Montgomery JM, Atherton J, O'Regan L, Richards MW, Straatman KR, Roth D, Straube A, Bayliss R, Moores CA, Fry AM
Sci Signal (2019) 12 [ Pubmed: 31409757 DOI: doi:10.1126/scisignal.aaw2939 ]
- Tubulin alpha-1b chain (50 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Homo sapiens)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Alpha and beta-tubulin from hela cell (modelled) decorated with eml4-ntd (not modelled) (110 MDa, Complex from Homo sapiens)
- Taxol (853 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5n5n
Q-score: 0.366
Vemu A, Atherton J, Spector JO, Moores CA, Roll-Mecak A
Mol Biol Cell (2017) 28 pp. 3564-3572 [ DOI: doi:10.1091/mbc.E17-02-0124 Pubmed: 29021343 ]
- Tubulin beta chain (47 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin alpha-1b chain (48 kDa, Protein from Homo sapiens)
- Human tsa201 cell tubulin microtubules (Complex from Homo sapiens)
Structure and dynamics of single-isoform recombinant neuronal human tubulin
Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 5jco
Q-score: 0.366
Vemu A, Atherton J, Spector JO, Szyk A, Moores CA, Roll-Mecak A
J Biol Chem (2016) 291 pp. 12907-12915 [ Pubmed: 27129203 DOI: doi:10.1074/jbc.C116.731133 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha-1a chain (48 kDa, Protein from Homo sapiens)
- Microtubules (110 MDa, Cellular component from Homo sapiens)
- Tubulin beta-3 chain (47 kDa, Protein from Homo sapiens)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Magnesium ion (24 Da, Ligand)