P. berghei kinesin-8B motor domain in AMPPNP state bound to tubulin dimer
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7z2b
Q-score: 0.367
Liu T, Shilliday F, Cook AD, Zeeshan M, Brady D, Tewari R, Sutherland CJ, Roberts AJ, Moores CA
Nat Commun (2022) 13 pp. 6988-6988 [ DOI: doi:10.1038/s41467-022-34710-x Pubmed: 36384964 ]
- Magnesium ion (24 Da, Ligand)
- Kinesin-8, putative (38 kDa, Protein from Plasmodium berghei)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- P. berghei kinesin-8b motor domain in amppnp state bound to tubulin dimer (Complex from Plasmodium berghei)
- Detyrosinated tubulin alpha-1b chain (47 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (47 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
P. berghei kinesin-8B motor domain in no nucleotide state bound to tubulin dimer
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7z2a
Q-score: 0.253
Liu T, Shilliday F, Cook AD, Zeeshan M, Brady D, Tewari R, Sutherland CJ, Roberts AJ, Moores CA
Nat Commun (2022) 13 pp. 6988-6988 [ DOI: doi:10.1038/s41467-022-34710-x Pubmed: 36384964 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (47 kDa, Protein from Sus scrofa)
- Kinesin-8, putative (39 kDa, Protein from Plasmodium berghei)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Detyrosinated tubulin alpha-1b chain (47 kDa, Protein from Sus scrofa)
- P. berghei kinesin-8b motor domain in no nucleotide state bound to tubulin dimer (Complex from Plasmodium berghei)
- Magnesium ion (24 Da, Ligand)
P. falciparum kinesin-8B motor domain in no nucleotide bound to tubulin dimer
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7z2c
Q-score: 0.296
Liu T, Shilliday F, Cook AD, Zeeshan M, Brady D, Tewari R, Sutherland CJ, Roberts AJ, Moores CA
Nat Commun (2022) 13 pp. 6988-6988 [ Pubmed: 36384964 DOI: doi:10.1038/s41467-022-34710-x ]
- Magnesium ion (24 Da, Ligand)
- Kinesin-like protein (39 kDa, Protein from Plasmodium falciparum)
- P. falciparum kinesin-8b motor domain in no nucleotide state bound to tubulin dimer (Complex from Plasmodium berghei)
- Tubulin beta chain (47 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Detyrosinated tubulin alpha-1b chain (47 kDa, Protein from Sus scrofa)
Resolution: 4.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nb8
Q-score: 0.268
Cook AD, Roberts AJ, Atherton J, Tewari R, Topf M, Moores CA
J Biol Chem (2021) 297 pp. 101063-101063 [ DOI: doi:10.1016/j.jbc.2021.101063 Pubmed: 34375637 ]
- Kinesin-5 (Complex from Plasmodium falciparum (isolate 3D7))
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 14 protofilament microtubule of alpha/beta-tubulin dimers, with kinesin-5 motor domain bound 1:1 to tubulin dimers. (Complex)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Kinesin-5 (46 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Magnesium ion (24 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Alpha/beta-tubulin (Complex from Sus scrofa)
Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nba
Q-score: 0.268
Cook AD, Roberts AJ, Atherton J, Tewari R, Topf M, Moores CA
J Biol Chem (2021) 297 pp. 101063-101063 [ DOI: doi:10.1016/j.jbc.2021.101063 Pubmed: 34375637 ]
- 14 protofilament microtubule complexed with plasmodium falciparum kinesin-5 motor domain bound to amppnp. asymmetric unit. (Complex from Plasmodium falciparum (isolate NF54))
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Kinesin motor domain-containing protein,kinesin motor domain-containing protein (46 kDa, Protein from Plasmodium falciparum (isolate NF54))