Cryo-EM structure of Gi1-bound metabotropic glutamate receptor mGlu4
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8jd6
Q-score: 0.394
Wang X, Wang M, Xu T, Feng Y, Shao Q, Han S, Chu X, Xu Y, Lin S, Zhao Q, Wu B
Cell Res (2023) 33 pp. 762-774 [ DOI: doi:10.1038/s41422-023-00830-2 Pubmed: 37286794 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Gi1-bound metabotropic glutamate receptor mglu4 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-3 (40 kDa, Protein from Homo sapiens)
- N-(3-chlorophenyl)pyridine-2-carboxamide (232 Da, Ligand)
- Metabotropic glutamate receptor 4 (99 kDa, Protein from Homo sapiens)
- Scfv (27 kDa, Protein from Escherichia coli)
- Phosphoserine (185 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7aef
Q-score: 0.529
Xu J, Ericson CF, Lien YW, Rutaganira FUN, Eisenstein F, Feldmuller M, King N, Pilhofer M
Nat Microbiol (2022) 7 pp. 397-410 [ DOI: doi:10.1038/s41564-022-01059-2 Pubmed: 35165385 ]
- The baseplate complex of an extracellular contractile injection system in marine bacterium algoriphagus machipongonensis, applied 3-fold symmetry. (Complex from Algoriphagus machipongonensis)
- Baseplate protein (algo12) (107 kDa, Protein from Algoriphagus machipongonensis)
- Putative tail lysozyme (15 kDa, Protein from Algoriphagus machipongonensis)
- Inner protein (algo6) (5 kDa, Protein from Algoriphagus machipongonensis)
- Phage tail protein (16 kDa, Protein from Algoriphagus machipongonensis)
- Phosphoserine phosphatase serb (63 kDa, Protein from Algoriphagus machipongonensis)
- Baseplate_j domain-containing protein (119 kDa, Protein from Algoriphagus machipongonensis)
- Putative phage tail sheath protein fi (76 kDa, Protein from Algoriphagus machipongonensis)
- Lysm domain-containing protein (26 kDa, Protein from Algoriphagus machipongonensis)
- Phospholipid/glycerol acyltransferase (17 kDa, Protein from Algoriphagus machipongonensis)
Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu4
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7e9h
Q-score: 0.303
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, Liu J, Yang D, Wang MW, Zhao Q, Wu B
Nature (2021) 594 pp. 583-588 [ Pubmed: 34135510 DOI: doi:10.1038/s41586-021-03495-2 ]
- Complex of mglu4 homodimer with heterotrimeric gi3 protein in presence of antibody (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-3 (40 kDa, Protein from Homo sapiens)
- Metabotropic glutamate receptor 4 (99 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Phosphoserine (185 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)