CryoEM structure of a 2,3-hydroxycinnamic acid 1,2-dioxygenase MhpB in substrate bound form
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 9kti
Q-score: 0.603
Dong X, Xu M, Wu M, Wang Y, Cheng X, Jiang W, Zheng D, Omar AH, Cheng Y, Li A, Ma L, Xing Q
J Hazard Mater (2025) 488 pp. 137431-137431 [ DOI: doi:10.1016/j.jhazmat.2025.137431 Pubmed: 39892151 ]
- 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase (34 kDa, Protein from Escherichia coli K-12)
- 3-[2,3-bis(oxidanyl)phenyl]propanoic acid (182 Da, Ligand)
- The decamer complex of mhpb bound with its substrate (Complex from Escherichia coli K-12)
- Fe (ii) ion (55 Da, Ligand)
Structure of chanoclavine synthase from Claviceps fusiformis in complex with prechanoclavine
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 9jdc
Q-score: 0.693
Liu ZW, Wang T, Li X, Shen PP, Huang J-W, Chen C-C, Guo R-T
To Be Published
- Catalase easc (54 kDa, Protein from Claviceps fusiformis)
- Ergot alkaloid synthesis protein c (Complex from Claviceps fusiformis)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- (2~{s})-2-(methylamino)-3-[4-[(1~{e})-3-methylbuta-1,3-dienyl]-1~{h}-indol-3-yl]propanoic acid (284 Da, Ligand)
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8yak
Q-score: 0.652
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- (2~{s})-2-[[(3~{r})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (403 Da, Ligand)
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
- Pwadh-g88d-d344n (Complex from Pseudoxanthomonas wuyuanensis)
- Zinc ion (65 Da, Ligand)
CryoEM structure of Deinococcus radiodurans BphP photosensory module in Pr state
To Be Published
- Deinococcus radiodurans bphp (163 kDa, Complex from Deinococcus radiodurans)
- 3-[2-[(z)-[3-(2-carboxyethyl)-5-[(z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(z)-[(3e)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1h-pyrrol-3- yl]propanoic acid (585 Da, Ligand)
- Bacteriophytochrome (84 kDa, Protein from Deinococcus radiodurans)
Cryo-EM structure of the TUG-891 bound FFA4-Gq complex
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8t3o
Q-score: 0.511
Zhang X, Guseinov AA, Jenkins L, Li K, Tikhonova IG, Milligan G, Zhang C
Sci Adv (2024) 10 pp. eadj2384-eadj2384 [ DOI: doi:10.1126/sciadv.adj2384 Pubmed: 38198545 ]
- Free fatty acid receptor 4 (33 kDa, Protein from Homo sapiens)
- 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid (364 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- (2r)-1-{[(r)-hydroxy{[(1r,2r,3r,4r,5s,6r)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5z,8z,11z,14z)-icosa-5,8,11,14-tetraenoate (967 Da, Ligand)
- Guanine nucleotide-binding protein g(q) (26 kDa, Protein from Homo sapiens)
- Tug-891-ffa4-minigq complex (Complex from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
Cryo-EM structure of the GPI inositol-deacylase (PGAP1/Bst1) from Chaetomium thermophilum
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8k9q
Q-score: 0.563
Hong J, Li T, Chao Y, Xu Y, Zhu Z, Zhou Z, Gu W, Qu Q, Li D
Nat Commun (2024) 15 pp. 8-8 [ DOI: doi:10.1038/s41467-023-44568-2 Pubmed: 38167496 ]
- Gpi inositol-deacylase,fused thermostable green fluorescent protein (163 kDa, Protein from synthetic construct)
- (2~{s})-2-azanyl-3-[[(2~{r})-3-hexadecanoyloxy-2-[(~{z})-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid (762 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Gpi inositol-deacylase (163 kDa, Complex from Thermochaetoides thermophila)
Cryo-EM structure of ochratoxin A-detoxifying amidohydrolase ADH3 in complex with ochratoxin A
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ihs
Q-score: 0.645
Dai L, Niu D, Huang JW, Li X, Shen P, Li H, Xie Z, Min J, Hu Y, Yang Y, Guo RT, Chen CC
J Hazard Mater (2023) 458 pp. 131836-131836 [ DOI: doi:10.1016/j.jhazmat.2023.131836 Pubmed: 37331057 ]
- Zinc ion (65 Da, Ligand)
- Amidohydrolase family protein (45 kDa, Protein from Stenotrophomonas acidaminiphila)
- (2~{s})-2-[[(3~{r})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (403 Da, Ligand)
- Adh3 (Complex from Stenotrophomonas acidaminiphila)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8j85
Q-score: 0.568
Dai L, Niu D, Huang JW, Li X, Shen P, Li H, Xie Z, Min J, Hu Y, Yang Y, Guo RT, Chen CC
J Hazard Mater (2023) 458 pp. 131836-131836 [ DOI: doi:10.1016/j.jhazmat.2023.131836 Pubmed: 37331057 ]
- Zinc ion (65 Da, Ligand)
- Amidohydrolase family protein (45 kDa, Protein from Stenotrophomonas acidaminiphila)
- (2~{s})-2-[[(3~{r})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (403 Da, Ligand)
- Adh3 (Complex from Stenotrophomonas acidaminiphila)
Composite map of CryoEM structure of Arabidopsis thaliana phytochrome A
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8f5z
Q-score: 0.437
Burgie ES, Li H, Gannam ZTK, McLoughlin KE, Vierstra RD, Li H
Nat Plants (2023) 9 pp. 1116-1129 [ Pubmed: 37291396 DOI: doi:10.1038/s41477-023-01435-8 ]
- 3-[5-[[(3~{r},4~{r})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{h}-pyrrol-2-yl]methyl]-4-methyl-1~{h}-pyrrol-3-yl]propanoic acid (586 Da, Ligand)
- Phytochrome a (124 kDa, Protein from Arabidopsis thaliana)
- Phytochrome a (249 kDa, Complex from Arabidopsis thaliana)
Human olfactory receptor OR51E2 bound to propionate in complex with miniGs399
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8f76
Q-score: 0.52
Billesbolle CB, de March CA, van der Velden WJC, Ma N, Tewari J, Del Torrent CL, Li L, Faust B, Vaidehi N, Matsunami H, Manglik A
Nature (2023) 615 pp. 742-749 [ DOI: doi:10.1038/s41586-023-05798-y Pubmed: 36922591 ]
- Olfactory receptor 51e2 (36 kDa, Protein from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Or51e2-gs complex (100 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (30 kDa, Protein from Homo sapiens)
- Propanoic acid (74 Da, Ligand)