Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the Naproxen-bound state
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8jh5
Q-score: 0.44
To Be Published
- Binary complex of pin1 with nanobody (Complex from Arabidopsis thaliana)
- (2s)-2-(6-methoxynaphthalen-2-yl)propanoic acid (230 Da, Ligand)
- Nanobody (13 kDa, Protein from Escherichia coli)
- Auxin efflux carrier component 1 (67 kDa, Protein from Arabidopsis thaliana)
Human GPR34 -Gi complex bound to S3E-LysoPS
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8xbe
Q-score: 0.445
Izume T, Kawahara R, Uwamizu A, Chen L, Yaginuma S, Omi J, Kawana H, Hou F, Sano FK, Tanaka T, Kobayashi K, Okamoto HH, Kise Y, Ohwada T, Aoki J, Shihoya W, Nureki O
Nat Commun (2024) 15 pp. 902-902 [ DOI: doi:10.1038/s41467-024-45046-z Pubmed: 38326347 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Human gpr34-gi complex bound to s3e-lysops (Complex)
- (2~{s})-2-azanyl-3-[[(2~{r})-1-ethoxy-3-[(~{z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid (551 Da, Ligand)
- Probable g-protein coupled receptor 34 (45 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Probable g-protein coupled receptor 34 (Complex from Homo sapiens)
Human GPR34 -Gi complex bound to S3E-LysoPS, receptor focused
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 8xbg
Q-score: 0.42
Izume T, Kawahara R, Uwamizu A, Chen L, Yaginuma S, Omi J, Kawana H, Hou F, Sano FK, Tanaka T, Kobayashi K, Okamoto HH, Kise Y, Ohwada T, Aoki J, Shihoya W, Nureki O
Nat Commun (2024) 15 pp. 902-902 [ DOI: doi:10.1038/s41467-024-45046-z Pubmed: 38326347 ]
- Human gpr34-gi complex bound to s3e-lysops, receptor focused (Complex from Homo sapiens)
- (2~{s})-2-azanyl-3-[[(2~{r})-1-ethoxy-3-[(~{z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid (551 Da, Ligand)
- Probable g-protein coupled receptor 34 (45 kDa, Protein from Homo sapiens)
Cryo-EM structure of the TUG-891 bound FFA4-Gq complex
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8t3o
Q-score: 0.511
Zhang X, Guseinov AA, Jenkins L, Li K, Tikhonova IG, Milligan G, Zhang C
Sci Adv (2024) 10 pp. eadj2384-eadj2384 [ DOI: doi:10.1126/sciadv.adj2384 Pubmed: 38198545 ]
- Free fatty acid receptor 4 (33 kDa, Protein from Homo sapiens)
- 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid (364 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- (2r)-1-{[(r)-hydroxy{[(1r,2r,3r,4r,5s,6r)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5z,8z,11z,14z)-icosa-5,8,11,14-tetraenoate (967 Da, Ligand)
- Guanine nucleotide-binding protein g(q) (26 kDa, Protein from Homo sapiens)
- Tug-891-ffa4-minigq complex (Complex from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
Human GPR34 -Gi complex bound to M1, receptor focused
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8xbi
Q-score: 0.457
Izume T, Kawahara R, Uwamizu A, Chen L, Yaginuma S, Omi J, Kawana H, Hou F, Sano FK, Tanaka T, Kobayashi K, Okamoto HH, Kise Y, Ohwada T, Aoki J, Shihoya W, Nureki O
Nat Commun (2024) 15 pp. 902-902 [ DOI: doi:10.1038/s41467-024-45046-z Pubmed: 38326347 ]
- (2~{s})-2-azanyl-3-[[(2~{r})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid (617 Da, Ligand)
- Probable g-protein coupled receptor 34 (45 kDa, Protein from Homo sapiens)
- Human gpr34-gi complex bound to m1,receptor focused (Complex from Homo sapiens)
Cryo-EM structure of Arabidopsis phytochrome A.
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8iff
Q-score: 0.405
Wang J, Zhou C, Guan Z, Wang Q, Zhao J, Wang L, Zhang L, Zhang D, Deng XW, Ma L, Yin P
Cell Res (2023) 33 pp. 802-805 [ Pubmed: 37402899 DOI: doi:10.1038/s41422-023-00847-7 ]
- 3-[5-[[(3~{r},4~{r})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{h}-pyrrol-2-yl]methyl]-4-methyl-1~{h}-pyrrol-3-yl]propanoic acid (586 Da, Ligand)
- Phytochrome a (Complex from Arabidopsis thaliana)
- Phytochrome a (124 kDa, Protein from Arabidopsis thaliana)
Human olfactory receptor OR51E2 bound to propionate in complex with miniGs399
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8f76
Q-score: 0.52
Billesbolle CB, de March CA, van der Velden WJC, Ma N, Tewari J, Del Torrent CL, Li L, Faust B, Vaidehi N, Matsunami H, Manglik A
Nature (2023) 615 pp. 742-749 [ DOI: doi:10.1038/s41586-023-05798-y Pubmed: 36922591 ]
- Olfactory receptor 51e2 (36 kDa, Protein from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Or51e2-gs complex (100 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (30 kDa, Protein from Homo sapiens)
- Propanoic acid (74 Da, Ligand)
SARS-CoV-2 spike glycoprotein trimer in closed state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7wgv
Q-score: 0.513
Zhao MM, Zhu Y, Zhang L, Zhong G, Tai L, Liu S, Yin G, Lu J, He Q, Li MJ, Zhao RX, Wang H, Huang W, Fan C, Shuai L, Wen Z, Wang C, He X, Chen Q, Liu B, Xiong X, Bu Z, Wang Y, Sun F, Yang JK
Cell Discov (2022) 8 pp. 53- [ DOI: doi:10.1038/s41421-022-00419-w ]
- 3-[5-[(z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1h-pyrrol-2-yl]methyl]-4-methyl-1h-pyrrol-3-yl]propanoic acid (584 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 b.1.1.7 spike glycoprotein trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
- Linoleic acid (280 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 spike glycoprotein trimer in closed state after treatment with Cathepsin L
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7wgx
Q-score: 0.468
Zhao MM, Zhu Y, Zhang L, Zhong G, Tai L, Liu S, Yin G, Lu J, He Q, Li MJ, Zhao RX, Wang H, Huang W, Fan C, Shuai L, Wen Z, Wang C, He X, Chen Q, Liu B, Xiong X, Bu Z, Wang Y, Sun F, Yang JK
Cell Discov (2022) 8 pp. 53- [ DOI: doi:10.1038/s41421-022-00419-w ]
- 3-[5-[(z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1h-pyrrol-2-yl]methyl]-4-methyl-1h-pyrrol-3-yl]propanoic acid (584 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 b.1.1.7 spike glycoprotein trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7v6y
Q-score: 0.448
Luo Y, Wan G, Zhang X, Zhou X, Wang Q, Fan J, Cai H, Ma L, Wu H, Qu Q, Cong Y, Zhao Y, Li D
Structure (2021) 29 pp. 1286- [ Pubmed: 34174188 DOI: doi:10.1016/j.str.2021.06.004 ]
- Cholesterol (386 Da, Ligand)
- Protein patched homolog 1,protein patched homolog 1 (121 kDa, Protein from Mus musculus)
- Ptc1 in lipid nanodisc (160 MDa, Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (2s)-2-azanyl-3-[[(2s)-3-butanoyloxy-2-dec-9-enoyloxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid (481 Da, Ligand)