Pendrin in complex with chloride
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8sgw
Q-score: 0.556
Wang L, Hoang A, Gil-Iturbe E, Laganowsky A, Quick M, Zhou M
Nat Commun (2024) 15 pp. 346-346 [ Pubmed: 38184688 DOI: doi:10.1038/s41467-023-44612-1 ]
- Homodimer of pendrin (75 kDa, Cellular component from Sus scrofa)
- Pendrin (86 kDa, Protein from Sus scrofa)
- Decyl-beta-d-maltopyranoside (482 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
Pendrin in complex with iodide
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8sh3
Q-score: 0.544
Wang L, Hoang A, Gil-Iturbe E, Laganowsky A, Quick M, Zhou M
Nat Commun (2024) 15 pp. 346-346 [ Pubmed: 38184688 DOI: doi:10.1038/s41467-023-44612-1 ]
- Homodimer of pendrin (75 kDa, Cellular component from Sus scrofa)
- Pendrin (86 kDa, Protein from Sus scrofa)
- Cholesterol (386 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Iodide ion (126 Da, Ligand)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
Pendrin in complex with Niflumic acid
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8shc
Q-score: 0.536
Wang L, Hoang A, Gil-Iturbe E, Laganowsky A, Quick M, Zhou M
Nat Commun (2024) 15 pp. 346-346 [ Pubmed: 38184688 DOI: doi:10.1038/s41467-023-44612-1 ]
- Homodimer of pendrin (75 kDa, Cellular component from Sus scrofa)
- Pendrin (86 kDa, Protein from Sus scrofa)
- 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid (282 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
Pendrin in complex with bicarbonate
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8sie
Q-score: 0.574
Wang L, Hoang A, Gil-Iturbe E, Laganowsky A, Quick M, Zhou M
Nat Commun (2024) 15 pp. 346-346 [ Pubmed: 38184688 DOI: doi:10.1038/s41467-023-44612-1 ]
- Homodimer of pendrin (75 kDa, Cellular component from Sus scrofa)
- Pendrin (86 kDa, Protein from Sus scrofa)
- Decyl-beta-d-maltopyranoside (482 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Bicarbonate ion (61 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8uuk
Q-score: 0.567
Wang L, Hoang A, Gil-Iturbe E, Laganowsky A, Quick M, Zhou M
Nat Commun (2024) 15 pp. 346-346 [ Pubmed: 38184688 DOI: doi:10.1038/s41467-023-44612-1 ]
- Homodimer of pendrin (75 kDa, Cellular component from Sus scrofa)
- Pendrin (86 kDa, Protein from Sus scrofa)
- Cholesterol (386 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
Mouse Pendrin bound chloride in inward state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8hzn
Q-score: 0.406
Liu QY, Zhang X, Sun L, Chen ZG
To Be Published
- Pendrin (85 kDa, Protein from Mus musculus)
- Chloride ion (35 Da, Ligand)
- Mouse pendrin bound chloride in inward state (Complex from Mus musculus)
Mouse Pendrin in chloride and iodide buffer in inward state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7wl8
Q-score: 0.391
Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y, Sun L, Chen Z
Nat Commun (2023) 14 pp. 3012-3012 [ DOI: doi:10.1038/s41467-023-38303-0 Pubmed: 37230976 ]
- Pendrin (85 kDa, Protein from Mus musculus)
- Mouse pendrin in chloride and iodide buffer in inward state (Complex from Mus musculus)
Mouse Pendrin in chloride and iodide buffer in asymmetric state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7wlb
Q-score: 0.219
Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y, Sun L, Chen Z
Nat Commun (2023) 14 pp. 3012-3012 [ DOI: doi:10.1038/s41467-023-38303-0 Pubmed: 37230976 ]
- Pendrin (85 kDa, Protein from Mus musculus)
- Mouse pendrin in chloride and bicarbonate in inward state (Complex from Mus musculus)
Mouse Pendrin bound bicarbonate in inward state
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 7wk7
Q-score: 0.367
Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y, Sun L, Chen Z
Nat Commun (2023) 14 pp. 3012-3012 [ DOI: doi:10.1038/s41467-023-38303-0 Pubmed: 37230976 ]
- Pendrin (85 kDa, Protein from Mus musculus)
- Bicarbonate ion (61 Da, Ligand)
- Mouse pendrin bound bicarbonate in inward state (Complex from Mus musculus)