Electron Microscopy Data Bank

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Human C Complex Spliceosome - High-resolution CORE

Release date: Oct. 14, 2020
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6zym
Q-score: 0.498

Bertram K, El Ayoubi L, Dybkov O, Agafonov DE, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Luhrmann R

Mol Cell (2020) 80 pp. 127-139.e6 [ DOI: doi:10.1016/j.molcel.2020.09.012 Pubmed: 33007253 ]

Sample:

Corepressor interacting with rbpj 1 (52 kDa, Protein from Human)
Snw domain-containing protein 1 (61 kDa, Protein from Human)
Pre-mrna-splicing factor isy1 homolog (33 kDa, Protein from Human)
Human c complex spliceosome - high resolution core (Complex from Homo sapiens)
U2 snrna (60 kDa, RNA from Human)
Protein bud31 homolog (17 kDa, Protein from Human)
Cell division cycle 5-like protein (92 kDa, Protein from Human)
Crooked neck-like protein 1 (100 kDa, Protein from Human)
Pre-mrna-processing factor 17 (65 kDa, Protein from Human)
Wd repeat-containing protein 70 (73 kDa, Protein from Human)
Pre-mrna-splicing factor atp-dependent rna helicase prp16 (140 kDa, Protein from Human)
Pre-mrna-splicing factor cwc25 homolog (49 kDa, Protein from Human)
Splicing factor yju2 (21 kDa, Protein from Human)
U5 small nuclear ribonucleoprotein 40 kda protein (39 kDa, Protein from Human)
Magnesium ion (24 Da, Ligand)
Pre-mrna-splicing factor cwc22 homolog (105 kDa, Protein from Human)
116 kda u5 small nuclear ribonucleoprotein component (107 kDa, Protein from Human)
U6 snrna (25 kDa, RNA from Human)
Pre-mrna-processing-splicing factor 8 (207 kDa, Protein from Human)
Peptidyl-prolyl cis-trans isomerase-like 1 (18 kDa, Protein from Human)
Zinc ion (65 Da, Ligand)
Spliceosome-associated protein cwc15 homolog (26 kDa, Protein from Human)
Inositol hexakisphosphate (660 Da, Ligand)
Guanosine-5'-triphosphate (523 Da, Ligand)
U5 snrna (36 kDa, RNA from Human)
Pre-mrna-splicing factor rbm22 (25 kDa, Protein from Human)
Pleiotropic regulator 1 (57 kDa, Protein from Human)
Serine/arginine repetitive matrix protein 2 (300 kDa, Protein from Human)
Protein frg1 (29 kDa, Protein from Human)
Pre-mrna (103 kDa, RNA from Human)

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