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sample_name:"Pre-mRNA-splicing factor ISY1" AND xref_links:"go"
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Integrative Structure of the human intron lariat Spliceosome (ILS'')

Release date: Sept. 18, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8ro2
Q-score: 0.297

Vorlander MK, Rothe P, Kleifeld J, Cormack ED, Veleti L, Riabov-Bassat D, Fin L, Phillips AW, Cochella L, Plaschka C

Nature (2024) 632 pp. 443-450 [ DOI: doi:10.1038/s41586-024-07741-1 Pubmed: 38925148 ]

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The cryo-EM structure of human C complex

Release date: July 31, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8i0w
Q-score: 0.231

Zhan X, Lu Y, Shi Y

Nat Commun (2024) 15 pp. 6348-6348 [ DOI: doi:10.1038/s41467-024-50785-0 Pubmed: 39068178 ]

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Human spliceosomal PM5 C* complex

Release date: July 12, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8c6j
Q-score: 0.353

Dybkov O, Preussner M, El Ayoubi L, Feng VY, Harnisch C, Merz K, Leupold P, Yudichev P, Agafonov DE, Will CL, Girard C, Dienemann C, Urlaub H, Kastner B, Heyd F, Luehrmann R

Sci Adv (2023) 9 pp. eadf1785- [ Pubmed: 36867703 DOI: doi:10.1126/sciadv.adf1785 ]

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Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).

Release date: May 10, 2023
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 8ch6
Q-score: 0.154

Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V

Nature (2023) 617 pp. 842-850 [ Pubmed: 37165190 DOI: doi:10.1038/s41586-023-06049-w ]

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Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound, composite map

Release date: March 10, 2021
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7b9v
Q-score: 0.378

Wilkinson ME, Fica SM, Galej WP, Nagai K

Mol Cell (2021) 81 pp. 1439- [ Pubmed: 33705709 DOI: doi:10.1016/j.molcel.2021.02.021 ]

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Human C Complex Spliceosome - High-resolution CORE

Release date: Oct. 14, 2020
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6zym
Q-score: 0.498

Bertram K, El Ayoubi L, Dybkov O, Agafonov DE, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Luhrmann R

Mol Cell (2020) 80 pp. 127-139.e6 [ DOI: doi:10.1016/j.molcel.2020.09.012 Pubmed: 33007253 ]

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Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom

Release date: April 24, 2019
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6j6g
Q-score: 0.317

Wan R, Bai R, Yan C, Lei J, Shi Y

Cell (2019) 177 pp. 339-351.e13 [ Pubmed: 30879786 DOI: doi:10.1016/j.cell.2019.02.006 ]

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Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom

Release date: April 24, 2019
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6j6h
Q-score: 0.283

Wan R, Bai R, Yan C, Lei J, Shi Y

Cell (2019) 177 pp. 339-351.e13 [ Pubmed: 30879786 DOI: doi:10.1016/j.cell.2019.02.006 ]

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Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom

Release date: April 24, 2019
Resolution: 3.86 Å
EM Method: Single-particle
Fitted PDBs: 6j6n
Q-score: 0.248

Wan R, Bai R, Yan C, Lei J, Shi Y

Cell (2019) 177 pp. 339-351.e13 [ Pubmed: 30879786 DOI: doi:10.1016/j.cell.2019.02.006 ]

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Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom

Release date: April 24, 2019
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6j6q
Q-score: 0.261

Wan R, Bai R, Yan C, Lei J, Shi Y

Cell (2019) 177 pp. 339-351.e13 [ Pubmed: 30879786 DOI: doi:10.1016/j.cell.2019.02.006 ]

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