Core particle assembly intermediate 1 purified from Saccharomyces cerevisiae
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 9d0t
Q-score: 0.541
Kaur M, Chen X, Lee SY, Weaver TM, Freudenthal BD, Walters KJ, Roelofs J
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.04.621988 Pubmed: 39574619 ]
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome maturation factor ump1,myosin light chain kinase 2, skeletal/cardiac muscle (22 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae)
- Probable proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome activator blm10 (246 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome assembly intermediate (534 kDa, Complex from Saccharomyces cerevisiae)
Blm10-20S proteasome complex from pre1-1
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 9gbk
Q-score: 0.585
Mark E, Ramos PC, Kayser F, Hockendorff J, Dohmen RJ, Wendler P
Life Sci Alliance (2024) 7 [ DOI: doi:10.26508/lsa.202402865 Pubmed: 39260885 ]
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-6 (24 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae)
- Probable proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-2 (25 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-4 (24 kDa, Protein from Saccharomyces cerevisiae)
- Blm10-20s proteasome complex from pre1-1 (Complex)
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome activator blm10 (246 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-1 (21 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-5 (23 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit beta type-7 (25 kDa, Protein from Saccharomyces cerevisiae)
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae)
- Water (18 Da, Ligand)
- 20s proteasome core (Complex from Saccharomyces cerevisiae)
- Proteasome subunit beta type-4 (Complex from Saccharomyces cerevisiae)
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae)
Human PA28-20S proteasome complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7nao
Q-score: 0.512
Zhao J, Makhija S, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B, Cheng Y
PNAS (2022) 119 pp. e2207200119-e2207200119 [ DOI: doi:10.1073/pnas.2207200119 Pubmed: 35858375 ]
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 1 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Pa28-20s proteasome complex (Complex from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 2 (27 kDa, Protein from Homo sapiens)
Human PA28-20S-PA28 proteasome complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7nap
Q-score: 0.445
Zhao J, Makhija S, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B, Cheng Y
PNAS (2022) 119 pp. e2207200119-e2207200119 [ DOI: doi:10.1073/pnas.2207200119 Pubmed: 35858375 ]
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- Pa28-20s-pa28 proteasome complex (Complex from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 1 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 2 (27 kDa, Protein from Homo sapiens)
Human PA200-20S proteasome complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7naq
Q-score: 0.483
Zhao J, Makhija S, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B, Cheng Y
PNAS (2022) 119 pp. e2207200119-e2207200119 [ DOI: doi:10.1073/pnas.2207200119 Pubmed: 35858375 ]
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Pa200-20s proteasome complex (Complex from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 4 (211 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Human PA200-20S proteasome with MG-132
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8cvs
Q-score: 0.559
Zhao J, Makhija S, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B, Cheng Y
PNAS (2022) 119 pp. e2207200119-e2207200119 [ DOI: doi:10.1073/pnas.2207200119 Pubmed: 35858375 ]
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (21 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- N-[(benzyloxy)carbonyl]-l-leucyl-n-[(2s)-4-methyl-1-oxopentan-2-yl]-l-leucinamide (475 Da, Ligand)
- Pa200-20s proteasome (Complex from Homo sapiens)
- Proteasome activator complex subunit 4 (211 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
EM structure of human PA28gamma
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 7yqc
Q-score: 0.617
Chen DD, Hao J, Shen CH, Deng XM, Yun CH
Int J Biol Macromol (2022) 219 pp. 500-507 [ DOI: doi:10.1016/j.ijbiomac.2022.07.246 Pubmed: 35932807 ]
- Proteasome activator (Cellular component from Homo sapiens)
- Proteasome activator complex subunit 3 (29 kDa, Protein from Homo sapiens)
EM structure of human PA28gamma (wild-type)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yqd
Q-score: 0.496
Chen DD, Hao J, Shen CH, Deng XM, Yun CH
Int J Biol Macromol (2022) 219 pp. 500-507 [ DOI: doi:10.1016/j.ijbiomac.2022.07.246 Pubmed: 35932807 ]
- Proteasome activator (Cellular component from Homo sapiens)
- Proteasome activator complex subunit 3 (29 kDa, Protein from Homo sapiens)
PA28alpha-beta in complex with immunoproteasome
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7dr6
Q-score: 0.24
Chen J, Wang Y, Xu C, Chen K, Zhao Q, Wang S, Yin Y, Peng C, Ding Z, Cong Y
Nat Commun (2021) 12 pp. 739-739 [ DOI: doi:10.1038/s41467-021-21028-3 Pubmed: 33531497 ]
- Proteasome activator complex subunit 2 (27 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 1 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-10 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-9 (23 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-3 (23 kDa, Protein from Bos taurus)
- 20s proteasome purified from bovine spleen in complex of human pa28 (Complex from Bos taurus)
- Proteasome subunit beta type-1 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-8 (30 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-2 (22 kDa, Protein from Bos taurus)
Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7drw
Q-score: 0.179
Chen J, Wang Y, Xu C, Chen K, Zhao Q, Wang S, Yin Y, Peng C, Ding Z, Cong Y
Nat Commun (2021) 12 pp. 739-739 [ DOI: doi:10.1038/s41467-021-21028-3 Pubmed: 33531497 ]
- Proteasome activator complex subunit 2 (27 kDa, Protein from Homo sapiens)
- Proteasome activator complex subunit 1 (28 kDa, Protein from Homo sapiens)
- 20s immunoproteasome purified from bovine spleen (Complex from Bos taurus)
- Proteasome subunit beta type-9 (23 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-10 (29 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-3 (23 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-1 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-8 (30 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-2 (22 kDa, Protein from Bos taurus)