Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7ydh
Q-score: 0.437
Wang N, Qian Y, Xia R, Zhu X, Xiong Y, Zhang A, Guo C, He Y
Cell Chem Biol (2023) 30 pp. 1343-1353.e5 [ Pubmed: 37673067 DOI: doi:10.1016/j.chembiol.2023.08.003 ]
- Adhesion g protein-coupled receptor e5 subunit beta (34 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- G protein subunit 13 (gi2-mini-g13 chimera) (26 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (130 kDa, Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7ydm
Q-score: 0.54
Wang N, Qian Y, Xia R, Zhu X, Xiong Y, Zhang A, Guo C, He Y
Cell Chem Biol (2023) 30 pp. 1343-1353.e5 [ Pubmed: 37673067 DOI: doi:10.1016/j.chembiol.2023.08.003 ]
- Adhesion g protein-coupled receptor e5 subunit beta (34 kDa, Protein from Homo sapiens)
- Nb35 (Complex)
- Engineered mini-gaq (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (130 kDa, Complex from Homo sapiens)
- Gpcr/g-protein (Complex from Lama glama)
- Nb35 (17 kDa, Protein from Lama glama)
Cryo-EM structure of CD97/miniGs complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7ydp
Q-score: 0.357
Wang N, Qian Y, Xia R, Zhu X, Xiong Y, Zhang A, Guo C, He Y
Cell Chem Biol (2023) 30 pp. 1343-1353.e5 [ Pubmed: 37673067 DOI: doi:10.1016/j.chembiol.2023.08.003 ]
- Adhesion g protein-coupled receptor e5 subunit beta (34 kDa, Protein from Homo sapiens)
- Nb35 (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Engineered minigas (41 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (130 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein (Complex from Lama glama)
- Nb35 (17 kDa, Protein from Lama glama)
DHA-bound FFAR4 in complex with Gs
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8h4i
Q-score: 0.574
Yin H, Inoue A, Ma Z, Zhu X, Xia R, Xu Z, Wang N, Duan Y, Zhang A, Guo C, He Y
Cell Res (2023) 33 pp. 644-647 [ Pubmed: 37286793 DOI: doi:10.1038/s41422-023-00835-x ]
- Docosa-4,7,10,13,16,19-hexaenoic acid (328 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Engineered mini galpha-s subunit (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Lama glama)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Free fatty acid receptor 4 (40 kDa, Protein from Homo sapiens)
GW9508-bound FFAR4 in complex with Gq
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8h4k
Q-score: 0.545
Yin H, Inoue A, Ma Z, Zhu X, Xia R, Xu Z, Wang N, Duan Y, Zhang A, Guo C, He Y
Cell Res (2023) 33 pp. 644-647 [ Pubmed: 37286793 DOI: doi:10.1038/s41422-023-00835-x ]
- 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid (347 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Lama glama)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Free fatty acid receptor 4 (40 kDa, Protein from Homo sapiens)
- Engineered mini galpha-q subunit (41 kDa, Protein from Homo sapiens)
DHA-bound FFAR4 in complex with Gq
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8h4l
Q-score: 0.546
Yin H, Inoue A, Ma Z, Zhu X, Xia R, Xu Z, Wang N, Duan Y, Zhang A, Guo C, He Y
Cell Res (2023) 33 pp. 644-647 [ Pubmed: 37286793 DOI: doi:10.1038/s41422-023-00835-x ]
- Docosa-4,7,10,13,16,19-hexaenoic acid (328 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Lama glama)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Free fatty acid receptor 4 (40 kDa, Protein from Homo sapiens)
- Engineered mini galpha-q subunit (41 kDa, Protein from Homo sapiens)
TUG891-bound FFAR4 in complex with Gq
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8iys
Q-score: 0.502
Yin H, Inoue A, Ma Z, Zhu X, Xia R, Xu Z, Wang N, Duan Y, Zhang A, Guo C, He Y
Cell Res (2023) 33 pp. 644-647 [ Pubmed: 37286793 DOI: doi:10.1038/s41422-023-00835-x ]
- 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid (364 Da, Ligand)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Free fatty acid receptor 4 (40 kDa, Protein from Homo sapiens)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7x10
Q-score: 0.465
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Engineered g alpha 12 subunit (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (Complex from Homo sapiens)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7wy5
Q-score: 0.514
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Engineered mini g alpha q subunit (41 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Homo sapiens)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7wy8
Q-score: 0.504
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Nb35 (17 kDa, Protein from Lama glama)
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Nb35 (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein (Complex from Lama glama)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Engineered mini g alpha s subunit (41 kDa, Protein from Homo sapiens)