Histamine-bound H4R/Gi complex
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8jxt
Q-score: 0.472
Xia R, Shi S, Xu Z, Vischer HF, Windhorst AD, Qian Y, Duan Y, Liang J, Chen K, Zhang A, Guo C, Leurs R, He Y
Nat Commun (2024) 15 pp. 2493-2493 [ DOI: doi:10.1038/s41467-024-46840-5 Pubmed: 38509098 ]
- Phosphate ion (94 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Histamine h4 receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Histamine (111 Da, Ligand)
- Gpcr/g-protein complex (130 MDa, Complex from Homo sapiens)
Clozapine-bound H4R/Gi complex
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8jxv
Q-score: 0.447
Xia R, Shi S, Xu Z, Vischer HF, Windhorst AD, Qian Y, Duan Y, Liang J, Chen K, Zhang A, Guo C, Leurs R, He Y
Nat Commun (2024) 15 pp. 2493-2493 [ DOI: doi:10.1038/s41467-024-46840-5 Pubmed: 38509098 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Histamine h4 receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Clozapine (326 Da, Ligand)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (130 MDa, Complex from Homo sapiens)
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8jxw
Q-score: 0.513
Xia R, Shi S, Xu Z, Vischer HF, Windhorst AD, Qian Y, Duan Y, Liang J, Chen K, Zhang A, Guo C, Leurs R, He Y
Nat Commun (2024) 15 pp. 2493-2493 [ DOI: doi:10.1038/s41467-024-46840-5 Pubmed: 38509098 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Histamine h4 receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- 2-chloranyl-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine (327 Da, Ligand)
- Gpcr/g-protein complex (130 MDa, Complex from Homo sapiens)
Clobenpropit-bound H4R/Gi complex
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8jxx
Q-score: 0.515
Xia R, Shi S, Xu Z, Vischer HF, Windhorst AD, Qian Y, Duan Y, Liang J, Chen K, Zhang A, Guo C, Leurs R, He Y
Nat Commun (2024) 15 pp. 2493-2493 [ DOI: doi:10.1038/s41467-024-46840-5 Pubmed: 38509098 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Histamine h4 receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- 3-(1~{h}-imidazol-4-yl)propyl ~{n}'-[(4-chlorophenyl)methyl]carbamimidothioate (308 Da, Ligand)
- Gpcr/g-protein complex (130 MDa, Complex from Homo sapiens)
Cryo-EM structure of E.coli membrane protein complex
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7wi3
Q-score: 0.335
Qiao Z, Yokoyama T, Yan XF, Beh IT, Shi J, Basak S, Akiyama Y, Gao YG
Cell Rep (2022) 39 pp. 110890-110890 [ Pubmed: 35649372 DOI: doi:10.1016/j.celrep.2022.110890 ]
- Modulator of ftsh protease hflc (37 kDa, Protein from Escherichia coli K-12)
- Modulator of ftsh protease hflk (45 kDa, Protein from Escherichia coli K-12)
- E.coli protein complex (Complex from Escherichia coli (strain K12))
- Atp-dependent zinc metalloprotease ftsh (70 kDa, Protein from Escherichia coli K-12)
Cryo-EM structure of E.coli membrane protein complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7wi4
Q-score: 0.432
Qiao Z, Yokoyama T, Yan XF, Beh IT, Shi J, Basak S, Akiyama Y, Gao YG
Cell Rep (2022) 39 pp. 110890-110890 [ Pubmed: 35649372 DOI: doi:10.1016/j.celrep.2022.110890 ]
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- E.coli protein complex (Complex from Escherichia coli (strain K12))
- Zinc ion (65 Da, Ligand)
- Atp-dependent zinc metalloprotease ftsh (70 kDa, Protein from Escherichia coli K-12)
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7dhi
Q-score: 0.531
Yang F, Ling SL, Zhou YX, Zhang YN, Lv P, Liu SL, Fang W, Sun WJ, Hu LYA, Zhang L, Shi P, Tian C
Natl Sci Rev (2020) [ DOI: doi:10.1093/nsr/nwaa284 ]
- Water (18 Da, Ligand)
- Beta-2 adrenergic receptor (42 kDa, Protein from Homo sapiens)
- Salbutamol (239 Da, Ligand)
- Nb35 nanobody (17 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Cryo-em structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-gs protein complex. (151 MDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7dhr
Q-score: 0.472
Yang F, Ling SL, Zhou YX, Zhang YN, Lv P, Liu SL, Fang W, Sun WJ, Hu LYA, Zhang L, Shi P, Tian C
Natl Sci Rev (2020) [ DOI: doi:10.1093/nsr/nwaa284 ]
- Beta-2 adrenergic receptor (42 kDa, Protein from Homo sapiens)
- Nb35 nanobody (17 kDa, Protein from Lama glama)
- Cryo-em structure of the full agonist isoprenaline-bound beta2 adrenergic receptor-gs protein complex. (151 MDa, Complex from Homo sapiens)
- Isoprenaline (211 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
Saccharomyces cerevisiae spliceosomal E complex (UBC4)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6n7p
Q-score: 0.352
Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao R
Nature (2019) 573 pp. 375-380 [ DOI: doi:10.1038/s41586-019-1523-6 Pubmed: 31485080 ]
- U1 small nuclear ribonucleoprotein component snu71,u1 small nuclear ribonucleoprotein component snu71,snu71 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein c (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Nuclear cap-binding protein subunit 2 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubc4 pre-mrna (81 kDa, RNA from Saccharomyces cerevisiae S288C)
- U1 small nuclear ribonucleoprotein component prp42 (65 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing protein prp40 (69 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 56 kda u1 small nuclear ribonucleoprotein component (56 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Protein nam8 (57 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein a (40 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Protein luc7 (30 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Nuclear cap-binding protein complex subunit 1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing factor 39 (74 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Saccharomyces cerevisiae spliceosomal e complex (ebc4) (Complex from Saccharomyces cerevisiae)
- U1 small nuclear ribonucleoprotein 70 kda homolog (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 snrna (182 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))