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sample_name:"Protein transport protein SEC61" AND author_name:"J" AND author_name:"K"
Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex
Release date: March 1, 2023
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8b5l
Q-score: 0.505
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8b5l
Q-score: 0.505
Pauwels E, Shewakramani NR, De Wijngaert B, Camps A, Provinciael B, Stroobants J, Kalies KU, Hartmann E, Maes P, Vermeire K, Das K
Sci Adv (2023) 9 pp. eadf0797-eadf0797 [ Pubmed: 36867692 DOI: doi:10.1126/sciadv.adf0797 ]
Sample:
- Ribosomal protein l10 (24 kDa, Protein from rabbit)
- 60s ribosomal protein l21 (18 kDa, Protein from rabbit)
- Translocon-associated protein subunit beta (20 kDa, Protein from Rabbit)
- Ribosomal protein l19 (23 kDa, Protein from rabbit)
- 60s ribosomal protein l36 (12 kDa, Protein from rabbit)
- 60s ribosomal protein l7 (26 kDa, Protein from rabbit)
- 60s ribosomal protein l36a-like (12 kDa, Protein from rabbit)
- 60s ribosomal protein l35a (12 kDa, Protein from rabbit)
- 60s ribosomal protein l29 (26 kDa, Protein from rabbit)
- 60s ribosomal protein l34 (12 kDa, Protein from rabbit)
- Ribosomal protein l37 (10 kDa, Protein from rabbit)
- 60s ribosomal protein l14 (16 kDa, Protein from rabbit)
- Ribosomal protein l8 (28 kDa, Protein from rabbit)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l41 (3 kDa, Protein from rabbit)
- Translocon-associated protein subunit alpha (32 kDa, Protein from Rabbit)
- 60s ribosomal protein l4 (41 kDa, Protein from rabbit)
- Ribosomal protein l3 (45 kDa, Protein from rabbit)
- 5.8s rrna (50 kDa, RNA from rabbit)
- 60s ribosomal protein l18a (20 kDa, Protein from rabbit)
- 60s ribosomal protein l13 (24 kDa, Protein from rabbit)
- 60s ribosomal protein l28 (14 kDa, Protein from rabbit)
- Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Rabbit)
- 60s ribosomal protein l17 (17 kDa, Protein from rabbit)
- 60s ribosomal protein l39-like (6 kDa, Protein from rabbit)
- 60s ribosomal protein l27 (15 kDa, Protein from rabbit)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Ribosomal protein l18 (21 kDa, Protein from rabbit)
- Ribosomal protein l15 (24 kDa, Protein from rabbit)
- 60s ribosomal protein l22 (11 kDa, Protein from rabbit)
- 60s ribosomal protein l7a (36 kDa, Protein from rabbit)
- 60s ribosomal protein l30 (10 kDa, Protein from rabbit)
- 60s ribosomal protein l9 (21 kDa, Protein from rabbit)
- 80s ribosome complex with sec61 and trap (Complex from Canis lupus familiaris)
- 60s ribosomal protein l31 (12 kDa, Protein from rabbit)
- Ribosomal protein l26 (15 kDa, Protein from rabbit)
- Zinc ion (65 Da, Ligand)
- Ubiquitin-60s ribosomal protein l40 (6 kDa, Protein from rabbit)
- 60s ribosomal protein l38 (8 kDa, Protein from rabbit)
- 60s ribosomal protein l37a (10 kDa, Protein from rabbit)
- Signal sequence receptor subunit 3 (21 kDa, Protein from Rabbit)
- 5s rrna (38 kDa, RNA from rabbit)
- 60s ribosomal protein l27a (16 kDa, Protein from rabbit)
- 60s ribosomal protein l23 (13 kDa, Protein from rabbit)
- Ribosomal protein l32 (15 kDa, Protein from rabbit)
- 60s ribosomal protein l13a (23 kDa, Protein from rabbit)
- Translocon-associated protein subunit delta (18 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Rabbit)
- Ribosomal protein l24 (17 kDa, Protein from rabbit)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from rabbit)
- 60s ribosomal protein l35 (14 kDa, Protein from rabbit)
- 60s ribosomal protein l11 (19 kDa, Protein from rabbit)
- Ribosomal_l23en domain-containing protein (13 kDa, Protein from rabbit)
- 60s ribosomal protein l6 (33 kDa, Protein from rabbit)
Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147
Release date: Feb. 22, 2023
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8b6c
Q-score: 0.516
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8b6c
Q-score: 0.516
Pauwels E, Shewakramani NR, De Wijngaert B, Camps A, Provinciael B, Stroobants J, Kalies KU, Hartmann E, Maes P, Vermeire K, Das K
Sci Adv (2023) 9 pp. eadf0797-eadf0797 [ Pubmed: 36867692 DOI: doi:10.1126/sciadv.adf0797 ]
Sample:
- Ribosomal protein l10 (24 kDa, Protein from rabbit)
- 60s ribosomal protein l21 (18 kDa, Protein from rabbit)
- 80s ribosome complex with sec61 and inhibitor ck147 (Complex from Canis lupus familiaris)
- 60s ribosomal protein l36 (12 kDa, Protein from rabbit)
- 60s ribosomal protein l7 (26 kDa, Protein from rabbit)
- 60s ribosomal protein l36a-like (12 kDa, Protein from rabbit)
- 60s ribosomal protein l35a (12 kDa, Protein from rabbit)
- 60s ribosomal protein l40 (6 kDa, Protein from rabbit)
- 60s ribosomal protein l29 (26 kDa, Protein from rabbit)
- 60s ribosomal protein l34 (12 kDa, Protein from rabbit)
- Ribosomal protein l37 (10 kDa, Protein from rabbit)
- 60s ribosomal protein l19 (23 kDa, Protein from rabbit)
- 60s ribosomal protein l14 (16 kDa, Protein from rabbit)
- Ribosomal protein l8 (28 kDa, Protein from rabbit)
- 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{n},~{n}-dimethyl-aniline (616 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l41 (3 kDa, Protein from rabbit)
- 60s ribosomal protein l4 (41 kDa, Protein from rabbit)
- Ribosomal protein l3 (45 kDa, Protein from rabbit)
- 5.8s rrna (50 kDa, RNA from rabbit)
- 60s ribosomal protein l18a (20 kDa, Protein from rabbit)
- 60s ribosomal protein l13 (24 kDa, Protein from rabbit)
- 60s ribosomal protein l28 (14 kDa, Protein from rabbit)
- 60s ribosomal protein l22 (fragment) (11 kDa, Protein from rabbit)
- 60s ribosomal protein l17 (17 kDa, Protein from rabbit)
- 60s ribosomal protein l39-like (6 kDa, Protein from rabbit)
- 60s ribosomal protein l27 (15 kDa, Protein from rabbit)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from rabbit)
- 60s ribosomal protein l7a (36 kDa, Protein from rabbit)
- 60s ribosomal protein l30 (10 kDa, Protein from rabbit)
- 60s ribosomal protein l9 (21 kDa, Protein from rabbit)
- Ribosomal protein l26 (15 kDa, Protein from rabbit)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l38 (8 kDa, Protein from rabbit)
- 60s ribosomal protein l37a (10 kDa, Protein from rabbit)
- El18 (21 kDa, Protein from rabbit)
- Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from rabbit)
- 60s ribosomal protein l27a (16 kDa, Protein from rabbit)
- 5s rrna (38 kDa, RNA from rabbit)
- 60s ribosomal protein l23 (13 kDa, Protein from rabbit)
- Ribosomal protein l32 (15 kDa, Protein from rabbit)
- 60s ribosomal protein l13a (23 kDa, Protein from rabbit)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Rabbit)
- Ribosomal protein l24 (17 kDa, Protein from rabbit)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from rabbit)
- 60s ribosomal protein l35 (14 kDa, Protein from rabbit)
- 60s ribosomal protein l31 (12 kDa, Protein from rabbit)
- 60s ribosomal protein l11 (19 kDa, Protein from rabbit)
- Ribosomal_l23en domain-containing protein (13 kDa, Protein from rabbit)
- 60s ribosomal protein l6 (33 kDa, Protein from rabbit)
Structure of XBP1u-paused ribosome nascent chain complex with Sec61.
Release date: July 10, 2019
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6r7q
Q-score: 0.34
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6r7q
Q-score: 0.34
Shanmuganathan V, Schiller N, Magoulopoulou A, Cheng J, Braunger K, Cymer F, Berninghausen O, Beatrix B, Kohno K, Heijne GV, Beckmann R
eLife (2019) 8 [ Pubmed: 31246176 DOI: doi:10.7554/eLife.46267 ]
Sample:
- El30 (10 kDa, Protein from Oryctolagus cuniculus)
- Es21 (9 kDa, Protein from Oryctolagus cuniculus)
- P-trna (24 kDa, RNA from Saccharomyces cerevisiae)
- Ribosomal protein es25 (8 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein us15 (17 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s16 (16 kDa, Protein from Oryctolagus cuniculus)
- Es17 (15 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Sec61 (Cellular component from Canis lupus familiaris)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l26 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s30 (6 kDa, Protein from Oryctolagus cuniculus)
- El29 (13 kDa, Protein from Oryctolagus cuniculus)
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- El34 (12 kDa, Protein from Oryctolagus cuniculus)
- Es19 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (17 kDa, Protein from Oryctolagus cuniculus)
- 18s ribosomal rna (548 kDa, RNA from Oryctolagus cuniculus)
- 28s ribosomal rna (1 MDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (28 kDa, Protein from Oryctolagus cuniculus)
- E-trna (24 kDa, RNA from Saccharomyces cerevisiae)
- Es24 (14 kDa, Protein from Oryctolagus cuniculus)
- Ul6 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- Us13 (16 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s11 (17 kDa, Protein from Oryctolagus cuniculus)
- El22 (11 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (13 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (14 kDa, Protein from Oryctolagus cuniculus)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Canis lupus familiaris)
- 40s ribosomal protein s6 (27 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- Es10 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s9 (predicted) (21 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Ul2 (26 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- Ul11 (16 kDa, Protein from Oryctolagus cuniculus)
- Structure of xbp1u-paused ribosome nascent chain complex with sec61. (Complex)
- Us2 (24 kDa, Protein from Oryctolagus cuniculus)
- Us14 (6 kDa, Protein from Oryctolagus cuniculus)
- Ul4 (41 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s7 (21 kDa, Protein from Oryctolagus cuniculus)
- Us10 (11 kDa, Protein from Oryctolagus cuniculus)
- Messenger rna (1 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ul3 (45 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- El14 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- X-box-binding protein 1 (2 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
- El28 (14 kDa, Protein from Oryctolagus cuniculus)
- Trna (Cellular component from Saccharomyces cerevisiae)
- Ul23 (13 kDa, Protein from Oryctolagus cuniculus)
- X-box-binding protein 1 (Cellular component from Homo sapiens)
- Es31 (7 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s5 (21 kDa, Protein from Oryctolagus cuniculus)
- Ribosome (Complex from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- Protein transport protein sec61 subunit beta (3 kDa, Protein from Canis lupus familiaris)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)
- El19 (21 kDa, Protein from Oryctolagus cuniculus)
- El40 (6 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (10 kDa, Protein from Oryctolagus cuniculus)
- Us5 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- Ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
- Mrna (Cellular component from Homo sapiens)
- Ribosomal protein l14 (16 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l11 (19 kDa, Protein from Oryctolagus cuniculus)
- Us11 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein el43 (10 kDa, Protein from Oryctolagus cuniculus)
- Es26 (11 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (48 kDa, RNA from Oryctolagus cuniculus)
- El8 (27 kDa, Protein from Oryctolagus cuniculus)
- El31 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s3 (25 kDa, Protein from Oryctolagus cuniculus)
- Protein transport protein sec61 subunit alpha isoform 1 (50 kDa, Protein from Canis lupus familiaris)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein rack1 (34 kDa, Protein from Oryctolagus cuniculus)
- Us19 (14 kDa, Protein from Oryctolagus cuniculus)