SARS-CoV-2 spike trimer (6P) in complex with two H18 and two R1-32 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Sars-cov-2 spike trimer (6p) in complex with two h18 and two r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- R1-32 fab (Complex from Homo sapiens)
- H18 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- R1-32 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with three h18 and three r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- H18 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs (one RBD rotated)
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with three h18 and three r1-32 fabs (one rbd rotated) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- R1-32 fab (Complex from Homo sapiens)
- H18 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 S1 in complex with H18 and R1-32 Fab
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Sars-cov-2 s1 in complex with h18 and r1-32 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- R1-32 fab (Complex from Homo sapiens)
- Spike glycoprotein (74 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- H18 fab (Complex from Homo sapiens)
- Sars-cov-2 s1 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
Dimer of SARS-CoV-2 S1 in complex with H18 and R1-32 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Dimer of sars-cov-2 s1 in complex with h18 and r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of h18 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- R1-32 fab (Complex from Homo sapiens)
- Spike glycoprotein (74 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- H18 fab (Complex from Homo sapiens)
- Sars-cov-2 s1 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of h18 fab (25 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 wildtype spike trimer (6P) in complex with 3 YB9-258 Fabs and 3 R1-32 Fabs (3 RBD up)
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8hc4
Q-score: 0.221
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X
Nat Commun (2023) 14 pp. 1058-1058 [ DOI: doi:10.1038/s41467-023-36761-0 Pubmed: 36828833 ]
- Yb9-258 fab and r1-32 fab (Complex from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of yb9-258 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of yb9-258 (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 wildtype spike trimer with three rbd up in complex with three yb9-258 fab and three r1-32 fab (Complex)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
- Sars-cov-2 wildtype spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 wildtype S1 in complex with YB9-258 Fab and R1-32 Fab
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 8hc5
Q-score: 0.282
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X
Nat Commun (2023) 14 pp. 1058-1058 [ DOI: doi:10.1038/s41467-023-36761-0 Pubmed: 36828833 ]
- Yb9-258 fab and r1-32 fab (Complex from Homo sapiens)
- Heavy chain of yb9-258 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of yb9-258 (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 wildtype s1 in complex with yb9-258 fab and r1-32 fab (Complex)
- Sars-cov_2 wildtype s1 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (75 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)