Cryo-EM structure of CaRC-LH complex from Chloroflexus aurantiacus
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 8ydm
Q-score: 0.491
Huang G, Dong S, Ma L, Li L, Ju J, Wang MJ, Zhang JP, Sui SF, Qin X
J Integr Plant Biol (2025) [ Pubmed: 39912559 DOI: doi:10.1111/jipb.13853 ]
- Cytochrome c-554 (45 kDa, Protein from Chloroflexus aurantiacus J-10-fl)
- Manganese (ii) ion (54 Da, Ligand)
- Reaction center protein l chain (35 kDa, Protein from Chloroflexus aurantiacus J-10-fl)
- Gamma-carotene (536 Da, Ligand)
- Bacteriopheophytin a (889 Da, Ligand)
- Cryo-em structure of carc-lh complex from chloroflexus aurantiacus (Complex from Chloroflexus aurantiacus J-10-fl)
- 2-methyl-3-[(2e,6e,10e,14e,18e,22e,26e,30e,34e,38e)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione (921 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Hypothetical protein chain n (6 kDa, Protein from Chloroflexus aurantiacus J-10-fl)
- Reaction center protein m chain (34 kDa, Protein from Chloroflexus aurantiacus J-10-fl)
- Bacteriochlorophyll a (911 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Light-harvesting protein b-808/866 beta chain (6 kDa, Protein from Chloroflexus aurantiacus J-10-fl)
- Light-harvesting protein b-808/866 alpha chain (6 kDa, Protein from Chloroflexus aurantiacus J-10-fl)
Photosynthetic LH2-LH1 complex from the purple bacterium Halorhodospira halophila
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8z81
Q-score: 0.682
Tani K, Nagashima KVP, Kojima R, Kondo M, Kanno R, Satoh I, Kawakami M, Hiwatashi N, Nakata K, Nagashima S, Inoue K, Isawa Y, Morishita R, Takaichi S, Purba ER, Hall M, Yu LJ, Madigan MT, Mizoguchi A, Humbel BM, Kimura Y, Nagasawa Y, Dewa T, Wang-Otomo ZY
Nat Commun (2025) 16 pp. 1410-1410 [ DOI: doi:10.1038/s41467-024-55811-9 Pubmed: 39915441 ]
- Lh2-lh1 complex of halorhodospira halophila (Complex from Halorhodospira halophila)
- Antenna complex, alpha/beta subunit (7 kDa, Protein from Halorhodospira halophila)
- Antenna complex, alpha/beta subunit (6 kDa, Protein from Halorhodospira halophila)
- Spirilloxanthin (596 Da, Ligand)
- Antenna complex, alpha/beta subunit (8 kDa, Protein from Halorhodospira halophila)
- Antenna complex, alpha/beta subunit (7 kDa, Protein from Halorhodospira halophila)
- Bacteriochlorophyll a (911 Da, Ligand)
- Photosynthetic lh2-lh1 complex from the purple phototrophic bacterium halorhodospira halophila (Complex from Halorhodospira halophila)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Antenna complex, alpha/beta subunit (7 kDa, Protein from Halorhodospira halophila)
- Antenna complex, alpha/beta subunit (7 kDa, Protein from Halorhodospira halophila)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Full-length apo human voltage-gated sodium channel 1.8 (NaV1.8)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 9dbk
Q-score: 0.41
Neumann B, McCarthy S, Gonen S
Nat Commun (2025) 16 pp. 1459-1459 [ DOI: doi:10.1038/s41467-024-55764-z Pubmed: 39920100 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (225 kDa, Protein from Homo sapiens)
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
Full-length apo human voltage-gated sodium channel 1.8 (NaV1.8), class I
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 9dbl
Q-score: 0.399
Neumann B, McCarthy S, Gonen S
Nat Commun (2025) 16 pp. 1459-1459 [ DOI: doi:10.1038/s41467-024-55764-z Pubmed: 39920100 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (225 kDa, Protein from Homo sapiens)
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
Full-length apo human voltage-gated sodium channel 1.8 (NaV1.8), class II
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 9dbm
Q-score: 0.396
Neumann B, McCarthy S, Gonen S
Nat Commun (2025) 16 pp. 1459-1459 [ DOI: doi:10.1038/s41467-024-55764-z Pubmed: 39920100 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (225 kDa, Protein from Homo sapiens)
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 9dbn
Q-score: 0.416
Neumann B, McCarthy S, Gonen S
Nat Commun (2025) 16 pp. 1459-1459 [ DOI: doi:10.1038/s41467-024-55764-z Pubmed: 39920100 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel protein type 10 subunit alpha (225 kDa, Protein from Homo sapiens)
- Sodium channel protein type 10 subunit alpha in complex with beta/omega-theraphotoxin-tp1a (Complex)
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- Beta/omega-theraphotoxin-tp1a (Complex from Thrixopelma pruriens)
- Beta/omega-theraphotoxin-tp1a (3 kDa, Protein from Thrixopelma pruriens)
- Sodium channel protein type 10 subunit alpha (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Cholesterol (386 Da, Ligand)
Structure of LAT1-CD98hc-Fab170 in complex with BCH, consensus map
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 8kdg
Q-score: 0.424
To Be Published
- (1~{s},2~{r},4~{r})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid (155 Da, Ligand)
- Fab170 (Complex from Mus musculus)
- 4f2 cell-surface antigen heavy chain (68 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab170 heavy chain (24 kDa, Protein from Mus musculus)
- Large neutral amino acids transporter small subunit 1 (56 kDa, Protein from Homo sapiens)
- Fab170 light chain (24 kDa, Protein from Mus musculus)
- Lat1-cd98hc-fab170 (173 kDa, Complex)
- Lat1-cd98hc (Complex from Homo sapiens)
Structure of LAT1-CD98hc in complex with BCH, focused on TMD
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 8kdh
Q-score: 0.45
To Be Published
- (1~{s},2~{r},4~{r})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid (155 Da, Ligand)
- 4f2 cell-surface antigen heavy chain (68 kDa, Protein from Homo sapiens)
- Lat1-cd98hc-fab170 (173 kDa, Complex from Homo sapiens)
- Large neutral amino acids transporter small subunit 1 (56 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
Miotto MC, Weninger G, Dridi H, Yuan Q, Liu Y, Wronska A, Melville Z, Sittenfeld L, Reiken S, Marks AR
Sci Adv (2022) 8 pp. eabo1272-eabo1272 [ DOI: doi:10.1126/sciadv.abo1272 Pubmed: 35857850 ]