Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 9dzu
Q-score: 0.479
Chen X, Duan HD, Hoy MJ, Koteva K, Spitzer M, Guitor AK, Puumala E, Hu G, Yiu B, Chou S, Bian Z, Guo ABY, Sun S, Robbins N, Cook MA, Truant R, MacNeil LT, Brown ED, Kronstad JW, Cowen LE, Heitman J, Li H, Wright GD
bioRxiv (2025) [ Pubmed: 39829750 DOI: doi:10.1101/2025.01.06.630955 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (3r,4r,5s)-3,4-dihydroxy-5-[(1r,2r,3s,4s,5r,6r,10e,14z,16e,18z)-1,2,3,4,5-pentahydroxy-6,20,20-trimethylhenicosa-10,14,16,18-tetraen-1-yl]oxolan-2-one (526 Da, Ligand)
- Transcription regulator (45 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- Magnesium ion (24 Da, Ligand)
- Beryllium trifluoride ion (66 Da, Ligand)
- Phospholipid-transporting atpase (176 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- Apt1-cdc50 heterodimer bound with butyrolactol a (222 kDa, Complex from Cryptococcus neoformans var. grubii H99)
SIRT7-H3K36MTUnucleosome complex
Carlos MY, Babatunde E, Polina F, Esther S, Dongchun N, Henning S, Beat F
To Be Published
- Zinc ion (65 Da, Ligand)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- [[(2~{r},3~{a}~{r},5~{r},6~{r},6~{a}~{r})-2-(methylamino)-6-oxidanyl-2-(propylamino)-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxathiol-5-yl]methoxy-oxidanyl-phosphoryl] [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (673 Da, Ligand)
- Histone h3.2 (15 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- K36 structure (Complex from Homo sapiens)
- Histone h2a type 2-a (13 kDa, Protein from Homo sapiens)
- Dna (149-mer) (46 kDa, DNA from Homo sapiens)
- Nad-dependent protein deacetylase sirtuin-7 (45 kDa, Protein from Homo sapiens)
- Dna (149-mer) (45 kDa, DNA from Homo sapiens)
CryoEM structure of influenza A RNP-like particle single-stranded assembled with a 12-mer RNA.
Resolution: 3.32 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gan
Q-score: 0.493
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ Pubmed: 39673795 DOI: doi:10.1093/nar/gkae1211 ]
- Rna (5'-p(uc)6-fam3') (3 kDa, RNA from synthetic construct)
- Complex np-rna (Complex from Influenza A virus)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
CryoEM structure of influenza A RNP-like particle double-stranded assembled with a 12-mer RNA.
Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gap
Q-score: 0.303
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ Pubmed: 39673795 DOI: doi:10.1093/nar/gkae1211 ]
- Rna (5'-p(uc)6-fam3') (3 kDa, RNA from synthetic construct)
- Rna (Complex from synthetic construct)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Nucleoprotein (Complex from Influenza A virus)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Complex np-rna (Complex)
Resolution: 3.08 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gas
Q-score: 0.531
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ Pubmed: 39673795 DOI: doi:10.1093/nar/gkae1211 ]
- Rna (5'-p(uc)9-fam3') (5 kDa, RNA from synthetic construct)
- Rna (Complex from synthetic construct)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Nucleoprotein (Complex from Influenza A virus)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Complex np-rna (Complex)
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gat
Q-score: 0.437
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ Pubmed: 39673795 DOI: doi:10.1093/nar/gkae1211 ]
- Rna (5'-p(uc)9-fam3') (5 kDa, RNA from synthetic construct)
- Rna (Complex from synthetic construct)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Nucleoprotein (Complex from Influenza A virus)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Complex np-rna (Complex)
Resolution: 3.04 Å
EM Method: Helical reconstruction
Fitted PDBs: 9gav
Q-score: 0.518
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ, Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T
Nucleic Acids Res (2025) 53 [ Pubmed: 39673795 DOI: doi:10.1093/nar/gkae1211 ]
- Rna (5'-p(uc)9-fam3') (5 kDa, RNA from synthetic construct)
- Rna (Complex from synthetic construct)
- Nucleoprotein (56 kDa, Protein from Influenza A virus)
- Nucleoprotein (Complex from Influenza A virus)
- 2-[3,6-bis(oxidanylidene)-4,5-dihydroxanthen-9-yl]-4-[3-[(2r)-2-oxidanylpropoxy]propylcarbamoyl]benzoic acid (493 Da, Ligand)
- Complex np-rna (Complex)
open state RyR2 in detergent in complex with nanobody
Li C, Willegems K, Uchanski T, Pardon E, Steyaert J, Efremov RG
J Biol Chem (2024) 300 pp. 107734-107734 [ Pubmed: 39233227 DOI: doi:10.1016/j.jbc.2024.107734 ]
TM part of RyR2 in detergent in open state
Li C, Willegems K, Uchanski T, Pardon E, Steyaert J, Efremov RG
J Biol Chem (2024) 300 pp. 107734-107734 [ Pubmed: 39233227 DOI: doi:10.1016/j.jbc.2024.107734 ]
Leukotriene C4-bound Multidrug Resistance-associated Protein 2 (MRP2)
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 9c12
Q-score: 0.53
Koide E, Pietz HL, Beltran J, Chen J
Nat Commun (2025) 16 pp. 484-484 [ Pubmed: 39779684 DOI: doi:10.1038/s41467-024-55810-w ]
- Wild type mrp2 bound to its substrate, leukotriene c4 (Cell from Homo sapiens)
- (5~{s},6~{r},7~{e},9~{e},11~{z},14~{z})-6-[(2~{r})-2-[[(4~{s})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid (625 Da, Ligand)
- Atp-binding cassette sub-family c member 2 (174 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Unknown ligand (790 Da, Ligand)