Cryo-EM structure of Saccharomyces cerevisiae bc1 complex in pyraclostrobin-bound state
Resolution: 2.42 Å
EM Method: Single-particle
Fitted PDBs: 8yhq
Q-score: 0.599
Wang YX, Ye Y, Li ZW, Cui GR, Shi XX, Dong Y, Jiang JJ, Sun JY, Guan ZW, Zhang N, Wu QY, Wang F, Zhu XL, Yang GF
J Am Chem Soc (2024) 146 pp. 33903-33913 [ Pubmed: 39601138 DOI: doi:10.1021/jacs.4c12595 ]
- Cytochrome b-c1 complex subunit 8 (10 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 9, mitochondrial (6 kDa, Protein from Saccharomyces cerevisiae)
- (2r,5s,11r,14r)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate (834 Da, Ligand)
- Methyl ~{n}-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-~{n}-methoxy-carbamate (387 Da, Ligand)
- Cytochrome b-c1 complex subunit 2, mitochondrial (38 kDa, Protein from Saccharomyces cerevisiae)
- (1r)-2-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate (593 Da, Ligand)
- (1r)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate (592 Da, Ligand)
- Cytochrome b (43 kDa, Protein from Saccharomyces cerevisiae)
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate (691 Da, Ligand)
- 5-(3,7,11,15,19,23-hexamethyl-tetracosa-2,6,10,14,18,22-hexaenyl)-2,3-dimethoxy-6-methyl-benzene-1,4-diol (592 Da, Ligand)
- Cor1 isoform 1 (47 kDa, Protein from Saccharomyces cerevisiae)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- (5s,11r)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate (634 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (14 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae bc1 complex (Complex from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 10, mitochondrial (5 kDa, Protein from Saccharomyces cerevisiae)
- (1r)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate (564 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (20 kDa, Protein from Saccharomyces cerevisiae)
- Qcr6 isoform 1 (8 kDa, Protein from Saccharomyces cerevisiae)
- Quinol--cytochrome-c reductase (27 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of Saccharomyces cerevisiae bc1 complex in YF23694-bound state
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 8yin
Q-score: 0.53
Wang YX, Ye Y, Li ZW, Cui GR, Shi XX, Dong Y, Jiang JJ, Sun JY, Guan ZW, Zhang N, Wu QY, Wang F, Zhu XL, Yang GF
J Am Chem Soc (2024) 146 pp. 33903-33913 [ Pubmed: 39601138 DOI: doi:10.1021/jacs.4c12595 ]
- Cytochrome b-c1 complex subunit 8 (10 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 9, mitochondrial (6 kDa, Protein from Saccharomyces cerevisiae)
- (2r,5s,11r,14r)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate (834 Da, Ligand)
- Cryo-em structure of saccharomyces cerevisiae bc1 complex in yf23694-bound state (Complex from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 2, mitochondrial (38 kDa, Protein from Saccharomyces cerevisiae)
- (1r)-2-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate (593 Da, Ligand)
- (1r)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate (592 Da, Ligand)
- Cytochrome b (43 kDa, Protein from Saccharomyces cerevisiae)
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate (691 Da, Ligand)
- 5-(3,7,11,15,19,23-hexamethyl-tetracosa-2,6,10,14,18,22-hexaenyl)-2,3-dimethoxy-6-methyl-benzene-1,4-diol (592 Da, Ligand)
- Cor1 isoform 1 (47 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome c1, heme protein, mitochondrial (27 kDa, Protein from Saccharomyces cerevisiae)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- (5s,11r)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate (634 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (14 kDa, Protein from Saccharomyces cerevisiae)
- 1-[2-[(4,6-dimethyl-1,3-benzothiazol-2-yl)sulfanylmethyl]-3-methyl-phenyl]-4-methyl-1,2,3,4-tetrazol-5-one (397 Da, Ligand)
- Cytochrome b-c1 complex subunit 10, mitochondrial (5 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (20 kDa, Protein from Saccharomyces cerevisiae)
- Qcr6 isoform 1 (8 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of Saccharomyces cerevisiae bc1 complex in Metyltetraprole-bound state
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8zmt
Q-score: 0.621
Wang YX, Ye Y, Li ZW, Cui GR, Shi XX, Dong Y, Jiang JJ, Sun JY, Guan ZW, Zhang N, Wu QY, Wang F, Zhu XL, Yang GF
J Am Chem Soc (2024) 146 pp. 33903-33913 [ Pubmed: 39601138 DOI: doi:10.1021/jacs.4c12595 ]
- Cytochrome b-c1 complex subunit 8 (10 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 9, mitochondrial (6 kDa, Protein from Saccharomyces cerevisiae)
- (2r,5s,11r,14r)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate (834 Da, Ligand)
- Cytochrome b-c1 complex subunit 2, mitochondrial (38 kDa, Protein from Saccharomyces cerevisiae)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- (1r)-2-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate (593 Da, Ligand)
- (1r)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate (592 Da, Ligand)
- Cytochrome b (43 kDa, Protein from Saccharomyces cerevisiae)
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate (691 Da, Ligand)
- 5-(3,7,11,15,19,23-hexamethyl-tetracosa-2,6,10,14,18,22-hexaenyl)-2,3-dimethoxy-6-methyl-benzene-1,4-diol (592 Da, Ligand)
- Cor1 isoform 1 (47 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 6, mitochondrial (8 kDa, Protein from Saccharomyces cerevisiae)
- 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-1,2,3,4-tetrazol-5-one (396 Da, Ligand)
- Cytochrome c1, heme protein, mitochondrial (27 kDa, Protein from Saccharomyces cerevisiae)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- (5s,11r)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate (634 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (14 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit 10, mitochondrial (5 kDa, Protein from Saccharomyces cerevisiae)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (20 kDa, Protein from Saccharomyces cerevisiae)
- Cryo-em structure of saccharomyces cerevisiae bc1 complex in metyltetraprole-bound state (Complex from Saccharomyces cerevisiae)
The Arabidopsis CLCa transporter bound with chloride, ATP and PIP2
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8iab
Q-score: 0.617
Yang Z, Zhang X, Ye S, Zheng J, Huang X, Yu F, Chen Z, Cai S, Zhang P
Nat Commun (2023) 14 pp. 4879-4879 [ Pubmed: 37573431 DOI: doi:10.1038/s41467-023-40624-z ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- The arabidopsis clca transporter (Complex from Arabidopsis thaliana)
- Chloride ion (35 Da, Ligand)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Chloride channel protein clc-a (85 kDa, Protein from Arabidopsis thaliana)
The Arabidopsis CLCa transporter bound with nitrate, ATP and PIP2
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 8iad
Q-score: 0.532
Yang Z, Zhang X, Ye S, Zheng J, Huang X, Yu F, Chen Z, Cai S, Zhang P
Nat Commun (2023) 14 pp. 4879-4879 [ Pubmed: 37573431 DOI: doi:10.1038/s41467-023-40624-z ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- The arabidopsis clca transporter (Complex from Arabidopsis thaliana)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Nitrate ion (62 Da, Ligand)
- Chloride channel protein clc-a (85 kDa, Protein from Arabidopsis thaliana)
human KCNQ1-CaM-ML277-PIP2 complex in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7xnl
Q-score: 0.412
Ma D, Zhong L, Yan Z, Yao J, Zhang Y, Ye F, Huang Y, Lai D, Yang W, Hou P, Guo J
PNAS (2022) 119 pp. e2207067119-e2207067119 [ Pubmed: 36763058 DOI: doi:10.1073/pnas.2207067119 ]
- (2r)-n-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide (471 Da, Ligand)
- Calmodulin-3 (19 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 1 (76 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Human kcnq1-cam-ml277-pip2 complex in state a (Cellular component from Homo sapiens)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
human KCNQ1-CaM-ML277-PIP2 complex in state B
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7xnn
Q-score: 0.428
Ma D, Zhong L, Yan Z, Yao J, Zhang Y, Ye F, Huang Y, Lai D, Yang W, Hou P, Guo J
PNAS (2022) 119 pp. e2207067119-e2207067119 [ Pubmed: 36763058 DOI: doi:10.1073/pnas.2207067119 ]
- Human kcnq1-cam-ml277-pip2 complex in state b (Cellular component from Homo sapiens)
- (2r)-n-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide (471 Da, Ligand)
- Calmodulin-3 (19 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 1 (76 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)