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sample_name:"R2" AND author_orcid:"0000-0001-8335-1436"
Homomeric alpha3 glycine receptor in the presence of 1 mM glycine at pH 6.4 in a desensitized state
Release date: Nov. 13, 2024
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 9bu2
Q-score: 0.54
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 9bu2
Q-score: 0.54
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Homomeric alpha3 glycine receptor in the presence of 0.1 mM glycine in a desensitized state
Release date: Nov. 13, 2024
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9bu3
Q-score: 0.568
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9bu3
Q-score: 0.568
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Homomeric alpha3 glycine receptor in the presence of 0.1 mM glycine in an apo state.
Release date: Nov. 13, 2024
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 9bvh
Q-score: 0.597
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 9bvh
Q-score: 0.597
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Water (18 Da, Ligand)
Homomeric alpha3 glycine receptor in the presence of 1 mM glycine in an desensitized state.
Release date: Nov. 13, 2024
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9bvj
Q-score: 0.546
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9bvj
Q-score: 0.546
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Release date: Nov. 13, 2024
Resolution: 2.21 Å
EM Method: Single-particle
Fitted PDBs: 9bwb
Q-score: 0.634
Resolution: 2.21 Å
EM Method: Single-particle
Fitted PDBs: 9bwb
Q-score: 0.634
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Homomeric alpha3 glycine receptor in the presence of 0.1 mM glycine at pH 6.4 in an apo state
Release date: Nov. 13, 2024
Resolution: 2.19 Å
EM Method: Single-particle
Fitted PDBs: 9bwc
Q-score: 0.634
Resolution: 2.19 Å
EM Method: Single-particle
Fitted PDBs: 9bwc
Q-score: 0.634
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Release date: Nov. 13, 2024
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 9bwe
Q-score: 0.487
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 9bwe
Q-score: 0.487
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Release date: Nov. 13, 2024
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 9bwg
Q-score: 0.597
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 9bwg
Q-score: 0.597
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)
Release date: Nov. 13, 2024
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 9bzp
Q-score: 0.515
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 9bzp
Q-score: 0.515
Kindig K, Gibbs E, Chakrapani S
To Be Published
Sample:
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Water (18 Da, Ligand)
- Pentameric assembly of human glycine receptor subtype alpha3 (250 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-3 (55 kDa, Protein from Homo sapiens)
- 1,2-dimyristoyl-sn-glycero-3-phosphocholine (678 Da, Ligand)
- Glycine (75 Da, Ligand)