Rat Kir4.1 in complex with PIP2
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8i5m
Q-score: 0.486
Zhou X, Zhao C, Xu H, Xu Y, Zhan L, Wang P, He J, Lu T, Gu Y, Yang Y, Xu C, Chen Y, Liu Y, Zeng Y, Tian F, Chen Q, Xie X, Liu J, Hu H, Li J, Zheng Y, Guo J, Gao Z
Nat Chem Biol (2024) 20 pp. 857-866 [ DOI: doi:10.1038/s41589-024-01555-y Pubmed: 38355723 ]
- Rat kir4.1 in complex with pip2 (Complex from Rattus norvegicus)
- Atp-sensitive inward rectifier potassium channel 10 (38 kDa, Protein from Rattus norvegicus)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
Rat Kir4.1 in complex with PIP2 and Lys05
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8i5n
Q-score: 0.414
Zhou X, Zhao C, Xu H, Xu Y, Zhan L, Wang P, He J, Lu T, Gu Y, Yang Y, Xu C, Chen Y, Liu Y, Zeng Y, Tian F, Chen Q, Xie X, Liu J, Hu H, Li J, Zheng Y, Guo J, Gao Z
Nat Chem Biol (2024) 20 pp. 857-866 [ DOI: doi:10.1038/s41589-024-01555-y Pubmed: 38355723 ]
- Atp-sensitive inward rectifier potassium channel 10 (38 kDa, Protein from Rattus norvegicus)
- Rat kir4.1 in complex with pip2 and lys05 (Complex from Rattus norvegicus)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
Dog beta3 adrenergic receptor bound to mirabegron in complex with a miniGs heterotrimer
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 7dh5
Q-score: 0.55
Nagiri C, Kobayashi K, Tomita A, Kato M, Kobayashi K, Yamashita K, Nishizawa T, Inoue A, Shihoya W, Nureki O
Mol Cell (2021) 81 pp. 3205-3215.e5 [ Pubmed: 34314699 DOI: doi:10.1016/j.molcel.2021.06.024 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- 2-(2-azanyl-1,3-thiazol-4-yl)-n-[4-[2-[[(2r)-2-oxidanyl-2-phenyl-ethyl]amino]ethyl]phenyl]ethanamide (396 Da, Ligand)
- Beta-3 adrenergic receptor (42 kDa, Protein from Canis lupus familiaris)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Dog beta3 adrenergic receptor bound to mirabegron in complex with a minigs heterotrimer (Complex)
- Nanobody nb35 (Complex from unidentified)
- Beta-3 adrenergic receptor (Complex from Canis lupus familiaris)
- Nanobody nb35 (15 kDa, Protein from unidentified)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex from Homo sapiens)
Cryo-EM density of full-length rXKR9 in complex with a sybody at 3.66A
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 7p14
Q-score: 0.457
Straub MS, Alvadia C, Sawicka M, Dutzler R
eLife (2021) 10 [ DOI: doi:10.7554/eLife.69800 Pubmed: 34263724 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sybody (Complex from synthetic construct)
- Rxkr9 with sybody (17 kDa, Complex from Rattus norvegicus)
- Xk-related protein (43 kDa, Protein from Rattus norvegicus)
- Rxkr9 (Complex from Rattus norvegicus)
- Sybody (13 kDa, Protein from synthetic construct)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
EMDB: Cryo electron microscopy map of the ATP-gated rat P2X7 ion channel in the apo, closed state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6u9v
Q-score: 0.503
McCarthy AE, Yoshioka C, Mansoor SE
Cell (2019) 179 pp. 659-670.e13 [ DOI: doi:10.1016/j.cell.2019.09.017 Pubmed: 31587896 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- O-[(r)-[(2s)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-d-serine (764 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- P2x7 receptor ion channel (Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- P2x purinoceptor 7 (69 kDa, Protein from Rattus norvegicus)
Cryo electron microscopy map of the ATP-gated rat P2X7 ion channel in the ATP-bound, open state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6u9w
Q-score: 0.523
McCarthy AE, Yoshioka C, Mansoor SE
Cell (2019) 179 pp. 659-670.e13 [ DOI: doi:10.1016/j.cell.2019.09.017 Pubmed: 31587896 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- O-[(r)-[(2s)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-d-serine (764 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- P2x7 receptor ion channel (Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- P2x purinoceptor 7 (69 kDa, Protein from Rattus norvegicus)