BG505 GT1.1 SOSIP in complex with NHP Fabs 12C11 and RM20A3
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8sw3
Q-score: 0.564
Caniels TG, Medina-Ramirez M, Zhang S, Kratochvil S, Xian Y, Koo JH, Derking R, Samsel J, van Schooten J, Pecetta S, Lamperti E, Yuan M, Carrasco MR, Del Moral Sanchez I, Allen JD, Bouhuijs JH, Yasmeen A, Ketas TJ, Snitselaar JL, Bijl TPL, Martin IC, Torres JL, Cupo A, Shirreff L, Rogers K, Mason RD, Roederer M, Greene KM, Gao H, Silva CM, Baken IJL, Tian M, Alt FW, Pulendran B, Seaman MS, Crispin M, van Gils MJ, Montefiori DC, McDermott AB, Villinger FJ, Koup RA, Moore JP, Klasse PJ, Ozorowski G, Batista FD, Wilson IA, Ward AB, Sanders RW
Sci Immunol (2024) 9 pp. eadk9550-eadk9550 [ Pubmed: 39213338 DOI: doi:10.1126/sciimmunol.adk9550 ]
- Rm20a3 light chain variable region (11 kDa, Protein from Macaca)
- 12c11 light chain variable region (11 kDa, Protein from Macaca)
- Bg505 gt1.1 sosip gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
- 12c11 heavy chain variable region (14 kDa, Protein from Macaca)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rm20a3 heavy chain variable region (13 kDa, Protein from Macaca)
- Bg505 gt1.1 sosip in complex with 12c11 fab and rm20a3 fab (720 kDa, Complex from Macaca)
BG505 GT1.1 SOSIP in complex with NHP Fabs 21N13, 21M20 and RM20A3
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8sw4
Q-score: 0.567
Caniels TG, Medina-Ramirez M, Zhang S, Kratochvil S, Xian Y, Koo JH, Derking R, Samsel J, van Schooten J, Pecetta S, Lamperti E, Yuan M, Carrasco MR, Del Moral Sanchez I, Allen JD, Bouhuijs JH, Yasmeen A, Ketas TJ, Snitselaar JL, Bijl TPL, Martin IC, Torres JL, Cupo A, Shirreff L, Rogers K, Mason RD, Roederer M, Greene KM, Gao H, Silva CM, Baken IJL, Tian M, Alt FW, Pulendran B, Seaman MS, Crispin M, van Gils MJ, Montefiori DC, McDermott AB, Villinger FJ, Koup RA, Moore JP, Klasse PJ, Ozorowski G, Batista FD, Wilson IA, Ward AB, Sanders RW
Sci Immunol (2024) 9 pp. eadk9550-eadk9550 [ Pubmed: 39213338 DOI: doi:10.1126/sciimmunol.adk9550 ]
- Rm20a3 light chain variable region (11 kDa, Protein from Macaca)
- 21m20 heavy chain variable region (13 kDa, Protein from Macaca)
- Bg505 gt1.1 sosip gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
- 21n13 heavy chain variable region (14 kDa, Protein from Macaca)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 21n13 light chain variable region (11 kDa, Protein from Macaca)
- Rm20a3 heavy chain variable region (13 kDa, Protein from Macaca)
- Bg505 gt1.1 sosip in complex with 21n13 fab, 21m20 fab and rm20a3 fab (770 kDa, Complex from Macaca)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 21m20 light chain variable region (11 kDa, Protein from Macaca)