type I-C Cascade bound to ssDNA target
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8dfa
Q-score: 0.48
O'Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW
Mol Cell (2023) 83 pp. 746- [ DOI: doi:10.1016/j.molcel.2023.01.024 Pubmed: 36805026 ]
- Type i-c cascade bound to ssdna (Complex from Desulfovibrio vulgaris str. Hildenborough)
- Crispr-associated protein, ct1133 family (14 kDa, Protein from Desulfovibrio vulgaris str. Hildenborough)
- Pre-crrna processing endonuclease (25 kDa, Protein from Desulfovibrio vulgaris str. Hildenborough)
- Crispr-associated protein, ct1133 family (68 kDa, Protein from Desulfovibrio vulgaris str. Hildenborough)
- Crispr-associated protein, tm1801 family (32 kDa, Protein from Desulfovibrio vulgaris str. Hildenborough)
- Rna (46-mer) (14 kDa, RNA from Desulfovibrio vulgaris)
- Ts (5 kDa, Macromolecule from Desulfovibrio vulgaris)
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 7s7b
Q-score: 0.444
Cell (2022) 185 pp. 2132-2147.e26 [ DOI: doi:10.1016/j.cell.2022.04.016 Pubmed: 35688134 ]
- Zinc finger cchc domain-containing protein 8,zinc finger cchc domain-containing protein 8 (69 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna-binding protein 7 (9 kDa, Protein from Homo sapiens)
- Rna (46-mer) (14 kDa, RNA from synthetic construct)
- Exosome rna helicase mtr4 (118 kDa, Protein from Homo sapiens)
- Human nuclear exosome targeting (next)-rna substrate 1 complex (Complex from Homo sapiens)
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 6s8b
Q-score: 0.48
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J, Huang Q, Li Y, She Q, Montoya G
Mol Cell (2020) 79 pp. 741-757.e7 [ DOI: doi:10.1016/j.molcel.2020.07.008 Pubmed: 32730741 ]
- Crispr-associated protein, cmr3 family (36 kDa, Protein from Sulfolobus islandicus (strain REY15A))
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Crispr-associated ramp protein, cmr6 family (33 kDa, Protein from Sulfolobus islandicus (strain REY15A))
- Cmr1 (55 kDa, Protein from Sulfolobus islandicus REY15A)
- Cognate target rna (46-mer) (14 kDa, RNA from Sulfolobus islandicus REY15A)
- Crispr-associated ramp protein, cmr4 family (32 kDa, Protein from Sulfolobus islandicus (strain REY15A))
- Crispr-associated protein cmrx (19 kDa, Protein from Sulfolobus islandicus (strain REY15A))
- Crispr-associated protein, cmr2 family (120 kDa, Protein from Sulfolobus islandicus (strain REY15A))
- Manganese (ii) ion (54 Da, Ligand)
- Crispr-associated protein, cmr5 family (17 kDa, Protein from Sulfolobus islandicus (strain REY15A))
- Type iii-b cmr-beta ternary complex, cognate target rna and amppnp bound (900 kDa, Complex from Sulfolobus islandicus REY15A)
- Zinc ion (65 Da, Ligand)
- Crrna (16 kDa, RNA from Sulfolobus islandicus REY15A)