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sample_name:"RPB7" AND xref_links:"chembl" AND xref_links:"cpx"
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Paused elongation complex of mammalian RNA polymerase II with nucleosome (PEC2-nuc)

Release date: Feb. 5, 2025
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9j0n
Q-score: 0.316

Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine S

Sci Adv (2025) [ DOI: doi:10.1126/sciadv.adu0577 ]

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Arrested elongation complex of mammalian RNA polymerase II with nucleosome (AEC1-nuc)

Release date: Feb. 5, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j0o
Q-score: 0.313

Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine S

Sci Adv (2025) [ DOI: doi:10.1126/sciadv.adu0577 ]

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Arrested elongation complex of mammalian RNA polymerase II with nucleosome (AEC2-nuc)

Release date: Feb. 5, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j0p
Q-score: 0.311

Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine S

Sci Adv (2025) [ DOI: doi:10.1126/sciadv.adu0577 ]

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Structure of Sen1 bound RNA Polymerase II pre-termination complex

Release date: Oct. 30, 2024
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ram
Q-score: 0.394

Rengachari S, Hainthaler T, Oberthuer C, Lidschreiber M, Cramer P

Nat Struct Mol Biol (2025) 32 pp. 339-345 [ Pubmed: 39424994 DOI: doi:10.1038/s41594-024-01409-0 ]

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Structure of Sen1-ADP.BeF3 bound RNA Polymerase II pre-termination complex

Release date: Oct. 30, 2024
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8rap
Q-score: 0.24

Rengachari S, Hainthaler T, Oberthuer C, Lidschreiber M, Cramer P

Nat Struct Mol Biol (2025) 32 pp. 339-345 [ Pubmed: 39424994 DOI: doi:10.1038/s41594-024-01409-0 ]

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Structure of s. pombe RNA polymerase II in complex with DSIF and Rat1/Rai1

Release date: Oct. 23, 2024
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8qsz
Q-score: 0.539

Kus K, Carrique L, Kecman T, Fournier M, Hassanein SS, Aydin E, Kilchert C, Grimes JM, Vasiljeva L

Nat Commun (2025) 16 pp. 10-10 [ DOI: doi:10.1038/s41467-024-55063-7 Pubmed: 39746995 ]

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The RNA polymerase II elongation complex from Saccharomyces cerevisiae

Release date: Sept. 4, 2024
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 9ja1

Ma J, Yi G, Ye M, MacGregor-Chatwin C, Sheng Y, Lu Y, Li M, Li Q, Wang D, Gilbert RJC, Zhang P

Nat Commun (2024) 15 pp. 10304-10304 [ Pubmed: 39604363 DOI: doi:10.1038/s41467-024-53745-w ]

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RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt

Release date: April 17, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8s51
Q-score: 0.415

Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P

Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]

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RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt

Release date: April 17, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8s52
Q-score: 0.431

Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P

Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]

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RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure)

Release date: April 17, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8s54
Q-score: 0.368

Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P

Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]

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