Vibrio vulnificus MARTX effector duet (RDTND-RID) complexed with human Rac1 Q61L and calmodulin
Choi S, Lee Y, Park S, Jang SY, Park J, Oh DW, Kim SM, Kim TH, Lee GS, Cho C, Kim BS, Lee D, Kim EH, Cheong HK, Moon JH, Song JJ, Hwang J, Kim MH
Nat Commun (2024) 15 pp. 6218-6218 [ DOI: doi:10.1038/s41467-024-50650-0 Pubmed: 39043696 ]
- Calmodulin (Protein from Homo sapiens)
- Calmodulin (Complex from Homo sapiens)
- Rdtnd-rid effector duet complexed with ca2+cam and rac1q61l (Complex)
- Rac1 (Complex from Homo sapiens)
- Rdtnd-rid (Protein from Vibrio vulnificus)
- Rdtnd-rid (Complex from Vibrio vulnificus)
- Rac1 (Protein from Homo sapiens)
Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex
Resolution: 4.66 Å
EM Method: Single-particle
Fitted PDBs: 8zj2
Q-score: 0.231
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M
J Biol Chem (2024) 300 pp. 107459-107459 [ Pubmed: 38857861 DOI: doi:10.1016/j.jbc.2024.107459 ]
- Rho-related gtp-binding protein rhog (22 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Engulfment and cell motility protein 1 (84 kDa, Protein from Homo sapiens)
- Rhog/dock5/elmo1/rac1 complex (Complex from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (20 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Dedicator of cytokinesis protein 5 (191 kDa, Protein from Homo sapiens)
Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 1)
Resolution: 4.23 Å
EM Method: Single-particle
Fitted PDBs: 8zji
Q-score: 0.192
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M
J Biol Chem (2024) 300 pp. 107459-107459 [ Pubmed: 38857861 DOI: doi:10.1016/j.jbc.2024.107459 ]
- Engulfment and cell motility protein 1 (84 kDa, Protein from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (20 kDa, Protein from Homo sapiens)
- Dedicator of cytokinesis protein 5 (191 kDa, Protein from Homo sapiens)
- Dock5/elmo1/rac1 complex (Complex from Homo sapiens)
Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 2)
Resolution: 4.23 Å
EM Method: Single-particle
Fitted PDBs: 8zjj
Q-score: 0.211
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M
J Biol Chem (2024) 300 pp. 107459-107459 [ Pubmed: 38857861 DOI: doi:10.1016/j.jbc.2024.107459 ]
- Engulfment and cell motility protein 1 (84 kDa, Protein from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (20 kDa, Protein from Homo sapiens)
- Dedicator of cytokinesis protein 5 (191 kDa, Protein from Homo sapiens)
- Dock5/elmo1/rac1 complex (Complex from Homo sapiens)
Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 3)
Resolution: 4.23 Å
EM Method: Single-particle
Fitted PDBs: 8zjk
Q-score: 0.203
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M
J Biol Chem (2024) 300 pp. 107459-107459 [ Pubmed: 38857861 DOI: doi:10.1016/j.jbc.2024.107459 ]
- Engulfment and cell motility protein 1 (84 kDa, Protein from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (20 kDa, Protein from Homo sapiens)
- Dedicator of cytokinesis protein 5 (191 kDa, Protein from Homo sapiens)
- Dock5/elmo1/rac1 complex (Complex from Homo sapiens)
Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 4)
Resolution: 4.31 Å
EM Method: Single-particle
Fitted PDBs: 8zjl
Q-score: 0.211
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M
J Biol Chem (2024) 300 pp. 107459-107459 [ Pubmed: 38857861 DOI: doi:10.1016/j.jbc.2024.107459 ]
- Engulfment and cell motility protein 1 (84 kDa, Protein from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (20 kDa, Protein from Homo sapiens)
- Dedicator of cytokinesis protein 5 (191 kDa, Protein from Homo sapiens)
- Dock5/elmo1/rac1 complex (Complex from Homo sapiens)
Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 5)
Resolution: 4.52 Å
EM Method: Single-particle
Fitted PDBs: 8zjm
Q-score: 0.142
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M
J Biol Chem (2024) 300 pp. 107459-107459 [ Pubmed: 38857861 DOI: doi:10.1016/j.jbc.2024.107459 ]
- Engulfment and cell motility protein 1 (84 kDa, Protein from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (20 kDa, Protein from Homo sapiens)
- Dedicator of cytokinesis protein 5 (191 kDa, Protein from Homo sapiens)
- Dock5/elmo1/rac1 complex (Complex from Homo sapiens)
